ID   A0A2K5IY08_COLAP        Unreviewed;       567 AA.
AC   A0A2K5IY08;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   18-JUN-2025, entry version 34.
DE   RecName: Full=C2H2-type domain-containing protein {ECO:0000259|PROSITE:PS50157};
OS   Colobus angolensis palliatus (Peters' Angolan colobus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Colobinae; Colobus.
OX   NCBI_TaxID=336983 {ECO:0000313|Ensembl:ENSCANP00000021397.1, ECO:0000313|Proteomes:UP000233080};
RN   [1] {ECO:0000313|Ensembl:ENSCANP00000021397.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (MAR-2025) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC       Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the Elbow/Noc family.
CC       {ECO:0000256|ARBA:ARBA00010144}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; A0A2K5IY08; -.
DR   STRING; 336983.ENSCANP00000021397; -.
DR   Ensembl; ENSCANT00000044372.1; ENSCANP00000021397.1; ENSCANG00000034128.1.
DR   OMA; SQAPHMD; -.
DR   Proteomes; UP000233080; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0045892; P:negative regulation of DNA-templated transcription; IEA:TreeGrafter.
DR   FunFam; 3.30.160.60:FF:000129; Zinc finger protein 503; 1.
DR   Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR   InterPro; IPR051520; Elbow/Noc_ZnFinger.
DR   InterPro; IPR022129; Tscrpt_rep_NocA-like.
DR   InterPro; IPR013087; Znf_C2H2_type.
DR   PANTHER; PTHR12522:SF2; ZINC FINGER PROTEIN 703; 1.
DR   PANTHER; PTHR12522; ZINC-FINGER PROTEIN NOLZ1-RELATED; 1.
DR   Pfam; PF12402; nlz1; 1.
DR   PROSITE; PS50157; ZINC_FINGER_C2H2_2; 1.
PE   3: Inferred from homology;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233080};
KW   Repressor {ECO:0000256|ARBA:ARBA00022491};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00042}.
FT   DOMAIN          434..467
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50157"
FT   REGION          98..271
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          319..344
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        106..117
FT                   /note="Low complexity"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        149..167
FT                   /note="Low complexity"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        185..197
FT                   /note="Low complexity"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        219..229
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        239..251
FT                   /note="Gly residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        319..330
FT                   /note="Gly residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   567 AA;  56229 MW;  23EADF20F1E6BCE9 CRC64;
     MFSEVCPTHF PGGGSRPVLC APANRLPIRV LKMLSAHTGH LLHPEYLQPL SSTPVSPIEL
     DAKKSPLALL AQTCSQIGKP DPPPSSKLNS VAAAANGLGA EKDPGRSAPG AASAAAALKQ
     LGDSPAEDKS SFKPYSKGSG GGDSRKDSGS SSVSSTSSSS SSSPGDKAGF RVPSAACPPF
     PPHGAPVSAS SSSSSPGGSR GGSPHHSDCK NGGGVGGGEL DKKDQEPKPS PEPAAVSRGS
     GGEPGAHGGA ESGASGRKSE PPSALVGAGH VAPVSPYKPG HSVFPLPPSS IGYHGSIVGA
     YAGYPSQFVP GLDPSKSGLV GGQLSGGLGL PPGKPPSSSP LTGASPPSFL QGLCRDPYCL
     GGYHGASHLG GSSCSTCSAH DPAGPSLKAG GYPLVYPGHP LQPAALSSSA AQAALPGHPL
     YTYGFMLQNE PLPHSCNWVA ASGPCDKRFA TSEELLSHLR THTALPGAEK LLAAYPGASG
     LGSAAAAAAA ASCHLHLPPP AAPGSPGSLS LRSPHTLGLS RYHPYGKSHL STAGGLAVPS
     LPTAGPYYSP YALYGQRLAS ASALGYQ
//