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Database: UniProt
Entry: A0A2K5IYR7_COLAP
LinkDB: A0A2K5IYR7_COLAP
Original site: A0A2K5IYR7_COLAP 
ID   A0A2K5IYR7_COLAP        Unreviewed;       679 AA.
AC   A0A2K5IYR7;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   08-MAY-2019, entry version 9.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSCANP00000021662};
GN   Name=ARAP1 {ECO:0000313|Ensembl:ENSCANP00000021662};
OS   Colobus angolensis palliatus (Peters' Angolan colobus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Cercopithecidae; Colobinae; Colobus.
OX   NCBI_TaxID=336983 {ECO:0000313|Ensembl:ENSCANP00000021662, ECO:0000313|Proteomes:UP000233080};
RN   [1] {ECO:0000313|Ensembl:ENSCANP00000021662, ECO:0000313|Proteomes:UP000233080}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Hughes D.S., Murali S., Raveendran M., Korchina V., Bandaranaike D.,
RA   Bellair M., Blankenburg K., Chao H., Dahdouli M., Dinh H.,
RA   Doddapaneni H., Gnanaolivu R., Gross S., Jayaseelan J., Jones J.,
RA   Khan Z., Kovar C., Kurapati P., Le B., Lee S., Mathew T.,
RA   Narasimhan A., Okwuonu G., Ongeri F., Osuji N., Qu C., Quiroz J.,
RA   Rajbhandari K., Reid J.G., Santibanez J., Skinner E., Wang Y., Xin Y.,
RA   Han Y., Muzny D.M., Richards S., Worley K.C., Rogers J., Gibbs R.A.;
RT   "Black and white colobus reference genome project.";
RL   Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSCANP00000021662}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2018) to UniProtKB.
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DR   Ensembl; ENSCANT00000044638; ENSCANP00000021662; ENSCANG00000033967.
DR   GeneTree; ENSGT00940000157424; -.
DR   Proteomes; UP000233080; Whole Genome Shotgun Assembly.
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   GO; GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   CDD; cd04385; RhoGAP_ARAP; 1.
DR   Gene3D; 1.10.555.10; -; 1.
DR   Gene3D; 2.30.29.30; -; 2.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR001849; PH_domain.
DR   InterPro; IPR000159; RA_dom.
DR   InterPro; IPR008936; Rho_GTPase_activation_prot.
DR   InterPro; IPR037858; RhoGAP_ARAP.
DR   InterPro; IPR000198; RhoGAP_dom.
DR   Pfam; PF00169; PH; 2.
DR   Pfam; PF00788; RA; 1.
DR   Pfam; PF00620; RhoGAP; 1.
DR   SMART; SM00233; PH; 3.
DR   SMART; SM00324; RhoGAP; 1.
DR   SUPFAM; SSF48350; SSF48350; 1.
DR   PROSITE; PS50003; PH_DOMAIN; 2.
DR   PROSITE; PS50200; RA; 1.
DR   PROSITE; PS50238; RHOGAP; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000233080};
KW   GTPase activation {ECO:0000256|SAAS:SAAS01175775};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233080}.
FT   DOMAIN        1     90       PH. {ECO:0000259|PROSITE:PS50003}.
FT   DOMAIN      194    379       Rho-GAP. {ECO:0000259|PROSITE:PS50238}.
FT   DOMAIN      412    501       Ras-associating. {ECO:0000259|PROSITE:
FT                                PS50200}.
FT   DOMAIN      514    625       PH. {ECO:0000259|PROSITE:PS50003}.
SQ   SEQUENCE   679 AA;  77670 MW;  EBBEFB5F068046E5 CRC64;
     MGASRKGKFS RRWCVLSDGV LSYYENERAV TPNGEIRASE IVCLAVPLPD THGFEHTFEV
     YTEGERLYLF GLESMEQAHE WVKCIAKAFV PPLAEDLLAR DFERLGRLPY KAGLSLQRAQ
     EGWFSLSGSE LRAVFPEGPC EEPLQLRKLQ ELSIQGDSEN QVLVLVERRR TLYIQGERRL
     DFMGWLGAIQ KAAASMGDTL SEQQLGDSDI PVIVYRCVDY ITQCGLTSEG IYRKCGQTSK
     TQRLLESLRQ DARSVHLKEG EQHVDDVSSA LKRFLRDLPD GLFTRAQRLA WLEASEIEDE
     EEKVSRYREL LVQLPPVNRA TVKALISHLY CVQCFSDTNQ MNVHNLAIVF GPTLFQTDGQ
     DYKAGRVVED LINHYVVVFS VDEEELRKQR EEITAIVKMR VAGTASGTQH AGDFICTVYL
     EEKKAETEQH VKIPASMTAE ELTLEILDRR NVGIREKDYW TCFEVNEREE AERPLHFAEK
     VLPILHGLGT DSHLVVKKHQ AMEAMLLYLA SRISDTKHGM MKFREDRSLL GLGLPSGGFH
     DRYFILNSSC LRLYKEVRSH RPEKEWPVKS LKVYLGVKKK LRPPTCWGFT VVHETEKHEK
     QQWYLCCDTQ MELREWFATF LFVQHDGLVW PSEPSRVSRA VPEVRLGSVS LIPLRGSENE
     MRRSVAAFSA DPLSLLRNV
//
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