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Database: UniProt
Entry: A0A2K5IZT6_COLAP
LinkDB: A0A2K5IZT6_COLAP
Original site: A0A2K5IZT6_COLAP 
ID   A0A2K5IZT6_COLAP        Unreviewed;      1816 AA.
AC   A0A2K5IZT6;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   05-JUN-2019, entry version 11.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSCANP00000022027};
GN   Name=LAMA4 {ECO:0000313|Ensembl:ENSCANP00000022027};
OS   Colobus angolensis palliatus (Peters' Angolan colobus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Cercopithecidae; Colobinae; Colobus.
OX   NCBI_TaxID=336983 {ECO:0000313|Ensembl:ENSCANP00000022027, ECO:0000313|Proteomes:UP000233080};
RN   [1] {ECO:0000313|Ensembl:ENSCANP00000022027, ECO:0000313|Proteomes:UP000233080}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Hughes D.S., Murali S., Raveendran M., Korchina V., Bandaranaike D.,
RA   Bellair M., Blankenburg K., Chao H., Dahdouli M., Dinh H.,
RA   Doddapaneni H., Gnanaolivu R., Gross S., Jayaseelan J., Jones J.,
RA   Khan Z., Kovar C., Kurapati P., Le B., Lee S., Mathew T.,
RA   Narasimhan A., Okwuonu G., Ongeri F., Osuji N., Qu C., Quiroz J.,
RA   Rajbhandari K., Reid J.G., Santibanez J., Skinner E., Wang Y., Xin Y.,
RA   Han Y., Muzny D.M., Richards S., Worley K.C., Rogers J., Gibbs R.A.;
RT   "Black and white colobus reference genome project.";
RL   Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSCANP00000022027}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2018) to UniProtKB.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00122}.
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DR   RefSeq; XP_011790422.1; XM_011935032.1.
DR   Ensembl; ENSCANT00000045006; ENSCANP00000022027; ENSCANG00000034417.
DR   GeneID; 105506752; -.
DR   CTD; 3910; -.
DR   GeneTree; ENSGT00940000159970; -.
DR   OrthoDB; 2342at2759; -.
DR   Proteomes; UP000233080; Whole Genome Shotgun Assembly.
DR   GO; GO:0005604; C:basement membrane; IEA:Ensembl.
DR   GO; GO:0031594; C:neuromuscular junction; IEA:Ensembl.
DR   GO; GO:0043083; C:synaptic cleft; IEA:Ensembl.
DR   GO; GO:0005102; F:signaling receptor binding; IEA:InterPro.
DR   GO; GO:0001568; P:blood vessel development; IEA:Ensembl.
DR   GO; GO:0050873; P:brown fat cell differentiation; IEA:Ensembl.
DR   GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR   GO; GO:0120163; P:negative regulation of cold-induced thermogenesis; IEA:Ensembl.
DR   GO; GO:0030155; P:regulation of cell adhesion; IEA:InterPro.
DR   GO; GO:0030334; P:regulation of cell migration; IEA:InterPro.
DR   GO; GO:0045995; P:regulation of embryonic development; IEA:InterPro.
DR   InterPro; IPR013320; ConA-like_dom_sf.
DR   InterPro; IPR000742; EGF-like_dom.
DR   InterPro; IPR009254; Laminin_aI.
DR   InterPro; IPR010307; Laminin_dom_II.
DR   InterPro; IPR002049; Laminin_EGF.
DR   InterPro; IPR001791; Laminin_G.
DR   Pfam; PF00053; Laminin_EGF; 3.
DR   Pfam; PF02210; Laminin_G_2; 5.
DR   Pfam; PF06008; Laminin_I; 1.
DR   Pfam; PF06009; Laminin_II; 1.
DR   SMART; SM00181; EGF; 3.
DR   SMART; SM00180; EGF_Lam; 3.
DR   SMART; SM00282; LamG; 5.
DR   SUPFAM; SSF49899; SSF49899; 5.
DR   PROSITE; PS01248; EGF_LAM_1; 1.
DR   PROSITE; PS50027; EGF_LAM_2; 3.
DR   PROSITE; PS50025; LAM_G_DOMAIN; 5.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000233080};
KW   Disulfide bond {ECO:0000256|PROSITE-ProRule:PRU00460,
KW   ECO:0000256|SAAS:SAAS00814887};
KW   Laminin EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00460,
KW   ECO:0000256|SAAS:SAAS00580772};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233080};
KW   Repeat {ECO:0000256|SAAS:SAAS00814929};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     27       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        28   1816       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5014447083.
FT   DOMAIN       82    131       Laminin EGF-like. {ECO:0000259|PROSITE:
FT                                PS50027}.
FT   DOMAIN      132    186       Laminin EGF-like. {ECO:0000259|PROSITE:
FT                                PS50027}.
FT   DOMAIN      187    240       Laminin EGF-like. {ECO:0000259|PROSITE:
FT                                PS50027}.
FT   DOMAIN      826   1028       LAM_G_DOMAIN. {ECO:0000259|PROSITE:
FT                                PS50025}.
FT   DOMAIN     1040   1220       LAM_G_DOMAIN. {ECO:0000259|PROSITE:
FT                                PS50025}.
FT   DOMAIN     1227   1395       LAM_G_DOMAIN. {ECO:0000259|PROSITE:
FT                                PS50025}.
FT   DOMAIN     1462   1633       LAM_G_DOMAIN. {ECO:0000259|PROSITE:
FT                                PS50025}.
FT   DOMAIN     1640   1813       LAM_G_DOMAIN. {ECO:0000259|PROSITE:
FT                                PS50025}.
FT   REGION     1413   1433       Disordered. {ECO:0000256|MobiDB-lite:
FT                                A0A2K5IZT6}.
FT   COILED      332    359       {ECO:0000256|SAM:Coils}.
FT   COILED      374    394       {ECO:0000256|SAM:Coils}.
FT   COILED      471    498       {ECO:0000256|SAM:Coils}.
FT   COILED      580    607       {ECO:0000256|SAM:Coils}.
FT   COILED      659    682       {ECO:0000256|SAM:Coils}.
FT   COILED      778    798       {ECO:0000256|SAM:Coils}.
FT   DISULFID    101    110       {ECO:0000256|PROSITE-ProRule:PRU00460}.
FT   DISULFID    157    166       {ECO:0000256|PROSITE-ProRule:PRU00460}.
FT   DISULFID    212    221       {ECO:0000256|PROSITE-ProRule:PRU00460}.
FT   DISULFID    224    238       {ECO:0000256|PROSITE-ProRule:PRU00460}.
SQ   SEQUENCE   1816 AA;  202090 MW;  7BAE40A66FA63E03 CRC64;
     MALSSAWCSV LPLWLLWSAA CSRAASGDDN AFPFDIEGSS AVGRQDPPET SEPRVALGRL
     PPAAEKCNAG FFRTLSGECV PCDCNGNSNE CLDGSGFCVH CQRNTTGERC EKCLDGYIGD
     SIRGAPRFCQ PCPCPLPHLA NFAESCYRKN GAVRCICKEN YAGPNCERCA PGYYGNPLLI
     GSTCKKCDCS GNSDPNLIFE DCDEVTGQCR NCLRNTTGFK CERCAPGYYG DARIAKNCAV
     CNCGGGPCDS VTGECLEEGL EPPTGCDKCV WDLTDDLRLA ALSIEEGKSG VLSVSSGAAA
     HRHVNEINAT IYLLKTKLSE RENQYALRKI QINNAENTMK SLLSDVEELV EKENQASRKG
     QLVQKESMDT IKHASQLVEQ AHDMRDKIQE INNKMLYYGE EHEFSPKEIS EKLVLAQKML
     EEIRRRQPFF TQRELVDEEA DEAHELLSQA ESWQRLHNET RTLFPVVLEQ LDDYNAKLSD
     LQEALDQALN HVRDAEDMNR ATAARQRDHE KQQERVREQM EVVNMSLSTS ADSLTTPRLT
     LSELDGIIKN ASGIYAEIDG AKNELQVKLS NLSNLSHDLV QEAIDHAQEL QQEANELSRK
     LHSSDMNGLV QKALDASNVY ENIVNYVSEA NETAEFALNT TDRIYDAVSG IDTQIIYHKD
     ESENLLNQAR ELQAKAESSS DEAVADTSRR VGGALARKSV LKTRLSDAVK QLQAAERGDA
     QQRLGQSRLI TEEANRTTME VQQATAPMAN NLTNWSQNLQ HFDSSAYNTA VDSARDAVRN
     LTEVVPQLLD QLRTVEQKRP ASNVSASIQR IRELIAQTRS VASKIQVSMM FDGQSAVEVH
     PRTSMDDLKA FTSLSLYMKP PVKQPELTET ADQFILYLGS KNAKKEYMGL AIKNDNLVYI
     YNLGTKDVEI PLDSKPVSSW PAYFSIVKIE RVGKHGKVFL TVPSLSSTAE EKFIKKGEFS
     GDDSLLDLDP EDTAFYVGGV PSNFKLPNSL NLPGFVGCLE LATLNNDVIS LYNFKHIYNM
     DPSTSVPCAR DKLAFTQSRA ASYFFDGSGY AVVRDITKRG KFGQVTRFDI EVRTPADNGL
     ILLMVNGSMF FRLEMRNGYL HVFYDFGFSS GPVHLEDTLK KAQINDAKYH EISIIYHNDK
     KMILVVDRRH VKSMDNEKMK IPFTDIYIGG APPEILQSRT LRAHLPLDIN FRGCMKGFQF
     QKKDFNLLEQ TETLGVGYGC PEDSLISRRA YFNGQSFIAS IQKISFFDGF EGGFNFRTLQ
     PNGLLFYYAS GSDVFSISLD NGTVVMDVKG IKVQSVDKQY NDGLSHFVIT SVSPTRYELI
     VDKSRVGSKN PTKGKIEQTQ AGEKKFYFGG SPISAQYANF TGCISNAYFT RVDRDVEVED
     FQRYTEKVHT SLYECPIESS PLFLLHKKRK NLSKPKASQN KKGGKSKDAP SWDPVALKFP
     ERNTPRNSHC HLSNSPRAIE HAYQYGGTAN SRQEFEHLKG DFGAKSQFSI RLRTRSSHGM
     IFYVSDQEEN DFMTLFLAHG RLVYMFNVGH KKLKIRSQEK YNDGLWHDVI FIRERSSGRL
     VIDGLRVLEE SLPPTEATWK IKGPIYLGGV APGKAVKNVQ INSIYSFSGC LSNLQLNRAS
     ITSASQTFSV TPCFEGPMET GTYFSTEGGY VVLDESFNIG LKFEIAFEVR PRSSSGTLVH
     GHSVNGEYLN VHMKNGQVIV KVNNGIRDFS TSVTPKQSLC DGRWHRITVI RDSNVVQLDV
     DSEVNHVVGP LNPKPIDHRE PVFVGGVPES LLTPRLAPSK PFTGCIRHFV IDGHPVSFSK
     AALVSGAVSI NSCPAA
//
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