ID A0A2K5J231_COLAP Unreviewed; 966 AA.
AC A0A2K5J231;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=G-protein coupled receptors family 2 profile 2 domain-containing protein {ECO:0000259|PROSITE:PS50261};
OS Colobus angolensis palliatus (Peters' Angolan colobus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Colobinae; Colobus.
OX NCBI_TaxID=336983 {ECO:0000313|Ensembl:ENSCANP00000022983.1, ECO:0000313|Proteomes:UP000233080};
RN [1] {ECO:0000313|Ensembl:ENSCANP00000022983.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR RefSeq; XP_011795603.1; XM_011940213.1.
DR AlphaFoldDB; A0A2K5J231; -.
DR Ensembl; ENSCANT00000045967.1; ENSCANP00000022983.1; ENSCANG00000034898.1.
DR GeneID; 105510427; -.
DR CTD; 10149; -.
DR OrthoDB; 4370914at2759; -.
DR Proteomes; UP000233080; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:InterPro.
DR GO; GO:0007166; P:cell surface receptor signaling pathway; IEA:InterPro.
DR CDD; cd15444; 7tmB2_GPR64; 1.
DR Gene3D; 2.60.220.50; -; 1.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR046338; GAIN_dom_sf.
DR InterPro; IPR017981; GPCR_2-like_7TM.
DR InterPro; IPR000832; GPCR_2_secretin-like.
DR InterPro; IPR017983; GPCR_2_secretin-like_CS.
DR InterPro; IPR000203; GPS.
DR PANTHER; PTHR12011; ADHESION G-PROTEIN COUPLED RECEPTOR; 1.
DR PANTHER; PTHR12011:SF264; ADHESION G-PROTEIN COUPLED RECEPTOR G2; 1.
DR Pfam; PF00002; 7tm_2; 1.
DR Pfam; PF01825; GPS; 1.
DR PRINTS; PR00249; GPCRSECRETIN.
DR SMART; SM00303; GPS; 1.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR PROSITE; PS00650; G_PROTEIN_RECEP_F2_2; 1.
DR PROSITE; PS50261; G_PROTEIN_RECEP_F2_4; 1.
DR PROSITE; PS50221; GPS; 1.
PE 4: Predicted;
KW G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Reference proteome {ECO:0000313|Proteomes:UP000233080};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transducer {ECO:0000256|ARBA:ARBA00023040};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 630..653
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 665..687
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 693..714
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 734..756
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 784..813
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 834..854
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 860..882
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 628..883
FT /note="G-protein coupled receptors family 2 profile 2"
FT /evidence="ECO:0000259|PROSITE:PS50261"
SQ SEQUENCE 966 AA; 106272 MW; 37C474035824A6F0 CRC64;
MVFSGRQCGR VGRTEEVLLT FKIFLVIICL HVVLVTSLEE DTDNSSLSPP PAKLSVVSFA
PSSSGTPEVE TTSLNDVTLS LPPLNKTEKT KITIVKTFNA SGVKLQRNIC NLSSICNDSA
FFRGEIMFQY DRESTIPQNQ HITNGTLTGV LSLSELKRSE LNKTLQTLSE TYFIMCATAE
AQSTLNCTFT IKLNNTMNAC AVIAALERVK IRPMEHCCCS VRTPCPSSPE ELEKLQCDLQ
DPIVCLADHP RGPPFSSSQS IPVVPRATVL SQVPSATSFA EPPDYSPVTH NVLSTIGDIH
PLSPQPSAPI ASSPAIDMPP QSEMISSPMP QTHVSGTPPP VKASFSSPTV SAPANVITTS
APPVQTDIVN TSSISDLENQ VSQMEKALSF GSLEPNLAGE MINQVSKLLH SPPDMLAPLA
QRLLKVVDDI GLQLNFSNKT ISLTSPSLAL AVIRVNASSF NTTTFVAQDP ANLQVSLETQ
APENSIGTIT LPSSLMNNLP ANDMELASRV QFNFFETPAL FQDPSLENLS LISYVISSSV
ANLTVRNLTR NVTVTLKHVN PSQDELTVRC VFWDLGRNGG RGGWSDDGCS VKDRRLNETI
CTCSHLTSFG ILLDLSRTSV LPAQTMALTF ITYIGCGLSS IFLSVTLVTY VAFEKIRRDY
PSKILIQLCA ALLLLNLVFL LDSWIALYKM QGICISVAVF LHYFLLVSFT WMGLEAFHMY
LALVKVFNTY IRKYILKFCI VGWGVPAVVV TIILTISPDN YGLGSYGKFP NGSPDDFCWI
NNNAVFYITV VGYFCVIFLL NVSMFIVVLV QLCRIKKKKQ LGAQRKTSIQ DLRSIAGLTF
LLGITWGFAF FAWGPVNVTF MYLFAIFNTL QGFFIFIFYC VAKENVRKQW RRYLCCGKLR
LAENSGNAST ERNGVSFSVQ NGDVCLHDFT GKQHTFNEKE DSCNGKGRMA LRRTSKRGSL
HFIEQM
//
