ID   A0A2K5J3P0_COLAP        Unreviewed;       597 AA.
AC   A0A2K5J3P0;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   24-JAN-2024, entry version 23.
DE   RecName: Full=Integrator complex subunit 11 {ECO:0000256|ARBA:ARBA00016810};
DE   AltName: Full=Cleavage and polyadenylation-specific factor 3-like protein {ECO:0000256|ARBA:ARBA00029625};
OS   Colobus angolensis palliatus (Peters' Angolan colobus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Colobinae; Colobus.
OX   NCBI_TaxID=336983 {ECO:0000313|Ensembl:ENSCANP00000023425.1, ECO:0000313|Proteomes:UP000233080};
RN   [1] {ECO:0000313|Ensembl:ENSCANP00000023425.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the metallo-beta-lactamase superfamily. RNA-
CC       metabolizing metallo-beta-lactamase-like family. INTS11 subfamily.
CC       {ECO:0000256|ARBA:ARBA00007093}.
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DR   AlphaFoldDB; A0A2K5J3P0; -.
DR   Ensembl; ENSCANT00000046413.1; ENSCANP00000023425.1; ENSCANG00000034418.1.
DR   Proteomes; UP000233080; Unplaced.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   CDD; cd16291; INTS11-like_MBL-fold; 1.
DR   Gene3D; 3.40.50.10890; -; 1.
DR   Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR   InterPro; IPR022712; Beta_Casp.
DR   InterPro; IPR041897; INTS11-like_MBL-fold.
DR   InterPro; IPR048662; IntS11_C.
DR   InterPro; IPR001279; Metallo-B-lactamas.
DR   InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR   InterPro; IPR011108; RMMBL.
DR   PANTHER; PTHR11203; CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR FAMILY MEMBER; 1.
DR   PANTHER; PTHR11203:SF37; INTEGRATOR COMPLEX SUBUNIT 11; 1.
DR   Pfam; PF10996; Beta-Casp; 1.
DR   Pfam; PF21386; IntS11_C; 1.
DR   Pfam; PF16661; Lactamase_B_6; 1.
DR   Pfam; PF07521; RMMBL; 1.
DR   SMART; SM01027; Beta-Casp; 1.
DR   SMART; SM00849; Lactamase_B; 1.
DR   SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000233080}.
FT   DOMAIN          16..233
FT                   /note="Metallo-beta-lactamase"
FT                   /evidence="ECO:0000259|SMART:SM00849"
FT   DOMAIN          252..360
FT                   /note="Beta-Casp"
FT                   /evidence="ECO:0000259|SMART:SM01027"
SQ   SEQUENCE   597 AA;  66989 MW;  6E379D8E1ABE7BE8 CRC64;
     MPEIRVTPLG AGQDVGRSCI LVSIAGKNVM LDCGMHMGFN DDRRFPDFSY ITQNGRLTDF
     LDCVIISHFH LDHCGALPYF SEMVGYDGPI YMTHPTQAIC PILLEDYRKI AVDKKGEANF
     FTSQMIKDCM KKVVAVHLHQ TVQVDDELEI KAYYAGHVLG AAMFQIKVGS ESVVYTGDYN
     MTPDRHLGAA WIDKCRPNLL ITESTYATTI RDSKRCRERD FLKKVHETVE RGGKVAIAVV
     GTRALGYAGR VLLARMNLKV PIYFSTGLTE KANHYYKLFI PWTNQKIRKT FVQRNMFEFK
     HIKAFDRAFA DNPGPMVVFA TPGMLHAGQS LQIFRKWAGN EKNMVIMPGY CVQGTVGHKI
     LSGQRKLEME GRQVLEVKMQ VEYMSFSAHA DAKGIMQLVG QAEPESVLLV HGEAKKMEFL
     KQKIEQELRV SCYMPANGET VTLPTSPSIP VGISLGLLKR EMAQGLLPEA KKPRLLHGTL
     IMKDSNFRLV SSEQALKELG LAEHQLRFTC RVHLHDTRKE QEMALRVYSH LKSVLKDHCV
     QHLPDGSVTV ESILIQAAAP SEDPGTKVLL VSWTYQDEEL GSFLTSLLKK GLPQAPS
//