ID A0A2K5J4T9_COLAP Unreviewed; 484 AA.
AC A0A2K5J4T9;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=Threonine synthase-like 2 {ECO:0000256|ARBA:ARBA00021942};
OS Colobus angolensis palliatus (Peters' Angolan colobus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Colobinae; Colobus.
OX NCBI_TaxID=336983 {ECO:0000313|Ensembl:ENSCANP00000023914.1, ECO:0000313|Proteomes:UP000233080};
RN [1] {ECO:0000313|Ensembl:ENSCANP00000023914.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933,
CC ECO:0000256|PIRSR:PIRSR604450-51};
CC -!- SIMILARITY: Belongs to the threonine synthase family.
CC {ECO:0000256|ARBA:ARBA00005517}.
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DR RefSeq; XP_011808495.1; XM_011953105.1.
DR RefSeq; XP_011808496.1; XM_011953106.1.
DR AlphaFoldDB; A0A2K5J4T9; -.
DR STRING; 336983.ENSCANP00000023914; -.
DR Ensembl; ENSCANT00000046908.1; ENSCANP00000023914.1; ENSCANG00000035355.1.
DR GeneID; 105519669; -.
DR KEGG; cang:105519669; -.
DR CTD; 55258; -.
DR OMA; FDDCQDM; -.
DR OrthoDB; 275600at2759; -.
DR Proteomes; UP000233080; Unplaced.
DR CDD; cd01560; Thr-synth_2; 1.
DR Gene3D; 3.40.50.1100; -; 2.
DR Gene3D; 3.90.1380.10; Threonine synthase, N-terminal domain; 1.
DR InterPro; IPR029144; Thr_synth_N.
DR InterPro; IPR037158; Thr_synth_N_sf.
DR InterPro; IPR004450; Thr_synthase-like.
DR InterPro; IPR001926; TrpB-like_PALP.
DR InterPro; IPR036052; TrpB-like_PALP_sf.
DR NCBIfam; TIGR00260; thrC; 1.
DR PANTHER; PTHR42690; THREONINE SYNTHASE FAMILY MEMBER; 1.
DR PANTHER; PTHR42690:SF1; THREONINE SYNTHASE-LIKE 2; 1.
DR Pfam; PF00291; PALP; 1.
DR Pfam; PF14821; Thr_synth_N; 1.
DR SUPFAM; SSF53686; Tryptophan synthase beta subunit-like PLP-dependent enzymes; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000256|ARBA:ARBA00023239};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW ECO:0000256|PIRSR:PIRSR604450-51};
KW Reference proteome {ECO:0000313|Proteomes:UP000233080}.
FT DOMAIN 3..81
FT /note="Threonine synthase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF14821"
FT DOMAIN 103..399
FT /note="Tryptophan synthase beta chain-like PALP"
FT /evidence="ECO:0000259|Pfam:PF00291"
FT MOD_RES 113
FT /note="N6-(pyridoxal phosphate)lysine"
FT /evidence="ECO:0000256|PIRSR:PIRSR604450-51"
SQ SEQUENCE 484 AA; 54165 MW; 1C7DD614A17E065E CRC64;
MWYISTRGIA PRVNFEGALF SGYAPDGGLF MPEELPQLDR ETLCQWSTLS YPDLVKELCA
LFISSELIPK DDLNDLIDRA FSRFRHKEVV RLSRLKNGLN VLELWHGVTY AFKDLSLSCT
AQFLQYFLEK REKHVTVVVG TSGDTGSAAI ESVQGAKNVD IIVLLPKGHC TKIQELQMTT
VLKENVHVFG VEGNSDELDE PIKTVFADMA FVKKHNLMSL NSINWSRVLV QMAHHFFAYF
QCTPSLDTHP LPLVEVVVPT GAAGNLAAGY IAQKIGLPIR LVVAVNRNDI IHRTVQQGDF
SLSKAVKSTL ASAMDIQVPY NMERVFWLLS GSDSQVTRAL MEQFERTQSV NLPKELHSKL
SEVVTSESVS DEAITQTMGR CWDENQYLLC PHSAVAVNYH YQQMDRQQPS TPRCCLAPAS
AAKFPEAVLA AGLTPETPAE IVALEHKETR CTPMQRGDNW TLMLQDTIED LSRRWRGHAL
NASQ
//
