ID   A0A2K5J515_COLAP        Unreviewed;       631 AA.
AC   A0A2K5J515;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   24-JAN-2024, entry version 29.
DE   RecName: Full=FCS-type domain-containing protein {ECO:0000259|PROSITE:PS51024};
OS   Colobus angolensis palliatus (Peters' Angolan colobus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Colobinae; Colobus.
OX   NCBI_TaxID=336983 {ECO:0000313|Ensembl:ENSCANP00000024004.1, ECO:0000313|Proteomes:UP000233080};
RN   [1] {ECO:0000313|Ensembl:ENSCANP00000024004.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR   AlphaFoldDB; A0A2K5J515; -.
DR   STRING; 336983.ENSCANP00000024004; -.
DR   Ensembl; ENSCANT00000046999.1; ENSCANP00000024004.1; ENSCANG00000035348.1.
DR   OMA; NTDCNLP; -.
DR   Proteomes; UP000233080; Unplaced.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd20120; MBT_MBTD1_rpt1; 1.
DR   CDD; cd20123; MBT_MBTD1_rpt2; 1.
DR   CDD; cd20126; MBT_MBTD1_rpt3; 1.
DR   CDD; cd20129; MBT_MBTD1_rpt4; 1.
DR   Gene3D; 2.30.30.140; -; 4.
DR   Gene3D; 3.30.60.160; -; 1.
DR   InterPro; IPR004092; Mbt.
DR   InterPro; IPR012313; Znf_FCS.
DR   InterPro; IPR038603; Znf_FCS_sf.
DR   PANTHER; PTHR12247:SF79; MBT DOMAIN-CONTAINING PROTEIN 1; 1.
DR   PANTHER; PTHR12247; POLYCOMB GROUP PROTEIN; 1.
DR   Pfam; PF02820; MBT; 4.
DR   Pfam; PF21319; zf-FCS_1; 1.
DR   SMART; SM00561; MBT; 4.
DR   SUPFAM; SSF63748; Tudor/PWWP/MBT; 4.
DR   PROSITE; PS51079; MBT; 4.
DR   PROSITE; PS51024; ZF_FCS; 1.
PE   4: Predicted;
KW   Chromatin regulator {ECO:0000256|ARBA:ARBA00022853};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233080};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00367}.
FT   DOMAIN          45..80
FT                   /note="FCS-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51024"
FT   REPEAT          144..248
FT                   /note="MBT"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00459"
FT   REPEAT          256..352
FT                   /note="MBT"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00459"
FT   REPEAT          354..459
FT                   /note="MBT"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00459"
FT   REPEAT          467..563
FT                   /note="MBT"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00459"
FT   REGION          1..32
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          563..593
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          609..631
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        7..24
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        612..631
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   631 AA;  70818 MW;  30A122B83DD8BD73 CRC64;
     MFDGYDSCSE DTSSSSSSEE SEEEVAPLPS NLPIIKNNGQ VYTYPDGKSG MATCEMCGMV
     GVRDAFYSKT KRFCSVSCSR SYSSNSKKAS ILARLQGKPP TKKAKVLQKQ PLVAKLAAYA
     QYQATLQNQA KTKAGNIAVS MEGFSWGNYI NSNSFIAAPV TCFKHAPMGT CWGDISENVR
     VEVPNTDCSL PTKVFWIAGV VKLAGYNALL RYEGFENDSG LDFWCNICGS DIHPVGWCAA
     SGKPLVPPRT IQHKYTNWKA FLVKRLTGAK TLPPDFSQKV SESMQYPFKP CMRVEVVDKR
     HLCRTRVAVV ESVIGGRLRL VYEESEDRTD DFWCHMHSPL IHHIGWSRSI GHRFKRSDIT
     KKQDGHFDTP PHLFAKVKEV DQSGEWFKEG MKLEAIDPLN LSTICVATIR KVLADGFLMI
     GIDGSEAADG SDWFCYHATS PSIFPVGFCE INMIELTPPR GYTKLPFKWF DYLRETGSIA
     APVKLFNKDV PNHGFRVGMK LEAVDLMEPR LICVATVTRI IHRLLRIHFD GWEEEYDQWV
     DCESPDLYPV GWCQLTGYQL QPPASQSSRE NQSASSKQKK KAKSQQYKGH KKMTTLQLKE
     ELLDGEDYNF LQGASDQESN GSANFYIKQE P
//