ID A0A2K5J959_COLAP Unreviewed; 342 AA.
AC A0A2K5J959;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=Paired box protein Pax-9 {ECO:0000256|ARBA:ARBA00016206};
OS Colobus angolensis palliatus (Peters' Angolan colobus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Colobinae; Colobus.
OX NCBI_TaxID=336983 {ECO:0000313|Ensembl:ENSCANP00000025443.1, ECO:0000313|Proteomes:UP000233080};
RN [1] {ECO:0000313|Ensembl:ENSCANP00000025443.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- FUNCTION: Transcription factor required for normal development of
CC thymus, parathyroid glands, ultimobranchial bodies, teeth, skeletal
CC elements of skull and larynx as well as distal limbs.
CC {ECO:0000256|ARBA:ARBA00002731}.
CC -!- SUBUNIT: Interacts with KDM5B. {ECO:0000256|ARBA:ARBA00011734}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A2K5J959; -.
DR STRING; 336983.ENSCANP00000025443; -.
DR Ensembl; ENSCANT00000048446.1; ENSCANP00000025443.1; ENSCANG00000036123.1.
DR Proteomes; UP000233080; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00131; PAX; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 2.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR043182; PAIRED_DNA-bd_dom.
DR InterPro; IPR001523; Paired_dom.
DR InterPro; IPR043565; PAX_fam.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR45636; PAIRED BOX PROTEIN PAX-6-RELATED-RELATED; 1.
DR PANTHER; PTHR45636:SF13; PAIRED BOX PROTEIN PAX-9; 1.
DR Pfam; PF00292; PAX; 1.
DR PRINTS; PR00027; PAIREDBOX.
DR SMART; SM00351; PAX; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS00034; PAIRED_1; 1.
DR PROSITE; PS51057; PAIRED_2; 1.
PE 4: Predicted;
KW Paired box {ECO:0000256|ARBA:ARBA00022724};
KW Reference proteome {ECO:0000313|Proteomes:UP000233080};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 3..129
FT /note="Paired"
FT /evidence="ECO:0000259|PROSITE:PS51057"
SQ SEQUENCE 342 AA; 36444 MW; 6588CA17554C4A1E CRC64;
MPAFGEVNQL GGVFVNGRPL PNAIRLRIVE LAQLGIRPCD ISRQLRVSHG CVSKILARYN
ETGSILPGAI GGSKPRVTTP TVVKHIRTYK QRDPGIFAWE IRDRLLADGV CDKYNVPSVS
SISRILRNKI GNLAQQGHYD SYKQHQPTPQ PALPYNHIYS YPSPITAAAA KVPTPPGVPA
IPGSVALPRT WPSSHSVTDI LGIRSITDQG RVSDSSPYHS PKVEEWSSLG RNNFPATAPH
AVNGLEKGVL EQEAKYGQAP NGLPAVGSFV SASGMAPYPT PAQVSPYMTY SAAPSGYVAG
HGWQHAGSTP LSPHNCDIPA SLAFKGMQAA REGSHSVTAS AL
//
