ID   A0A2K5JF28_COLAP        Unreviewed;      1298 AA.
AC   A0A2K5JF28;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   RecName: Full=TOG domain-containing protein {ECO:0000259|SMART:SM01349};
OS   Colobus angolensis palliatus (Peters' Angolan colobus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Colobinae; Colobus.
OX   NCBI_TaxID=336983 {ECO:0000313|Ensembl:ENSCANP00000027478.1, ECO:0000313|Proteomes:UP000233080};
RN   [1] {ECO:0000313|Ensembl:ENSCANP00000027478.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   Ensembl; ENSCANT00000050496.1; ENSCANP00000027478.1; ENSCANG00000035687.1.
DR   Proteomes; UP000233080; Unplaced.
DR   GO; GO:0015630; C:microtubule cytoskeleton; IEA:UniProt.
DR   GO; GO:0008017; F:microtubule binding; IEA:UniProt.
DR   GO; GO:0051494; P:negative regulation of cytoskeleton organization; IEA:UniProt.
DR   GO; GO:1902904; P:negative regulation of supramolecular fiber organization; IEA:UniProt.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 3.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR024395; CLASP_N_dom.
DR   InterPro; IPR034085; TOG.
DR   PANTHER; PTHR21567; CLASP; 1.
DR   PANTHER; PTHR21567:SF30; CLIP-ASSOCIATING PROTEIN 2; 1.
DR   Pfam; PF21040; CEP104-like_TOG; 1.
DR   Pfam; PF12348; CLASP_N; 1.
DR   SMART; SM01349; TOG; 3.
DR   SUPFAM; SSF48371; ARM repeat; 2.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000233080}.
FT   DOMAIN          83..316
FT                   /note="TOG"
FT                   /evidence="ECO:0000259|SMART:SM01349"
FT   DOMAIN          652..889
FT                   /note="TOG"
FT                   /evidence="ECO:0000259|SMART:SM01349"
FT   DOMAIN          1055..1291
FT                   /note="TOG"
FT                   /evidence="ECO:0000259|SMART:SM01349"
FT   REGION          1..61
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          313..367
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          431..464
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          485..554
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          616..650
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          882..932
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          956..996
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..15
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        433..464
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        485..528
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        536..551
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        628..650
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        962..977
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1298 AA;  141682 MW;  5B74D61E52E11F18 CRC64;
     LILDKSFDDE ESVDGNRPSS AASAFKVPAP KTSGNPVNSA RKPGSAGGPK VGAGASKEGG
     AGAVDEDDFI KAFTDVPSVQ IYSSRELEET LNKIREILSD DKHDWDQRAN ALKKIRSLLV
     AGAAQYDCFF QHLRLLDGAL KLSAKDLRSQ VVREACITVA HLSTVLGNKF DHGAEAIVPT
     LFNLVPNSAK VMATSGCAAI RFIIRHTHVP RLIPLITSNC TSKSVPVRRR SFEFLDLLLQ
     EWQTHSLERH AAVLVETIKK GIHDADAEAR VEARKTYMGL RNHFPGEAET LYNSLEPSYQ
     KSLQTYLKSS GSVASLPQSD RSSSSSQESL NRPFSSKWST ANPSTVAGRV SAGSSKASSL
     PGSLQRSRSD IDVNAAAGAK AHHAAGQSVR NGRLGAGALN PGSYASLGTA SEDGKNYIFC
     RVRAKLSAPL TGMGNAKTDS RGRSRTKMVS QSQPGSRSGS PGRVLTTTAL STVSSGVQRV
     LVNSASAQKR SKIPRSQGCS REASPSRLSV ARSSRIPRPS VSQGCSREAS RESSRDTSPV
     RSFQPLASRH HSRSTGALYA PDVYGASGPG YGISQSSRLS SSVSAMRVLN TGSDVEEAVA
     DALLLGDIRT KKKPARRRYE SYGMHSDDDA NSDASSACSE RSYSSRNGSI PTYMRQTEDV
     AEVLNRCASS NWSERKEGLL GLQNLLKNQR TLSRVELKRL CEIFTRMFAD PHGKVFSMFL
     ETLVDFIQVH KDDLQDWLFV LLTQLLKKMG ADLLGSVQAK VQKALDVTRE SFPNDLQFNI
     LMRFTVDQTQ TPSLKVKVAI LKYIETLAKQ MDPGDFINSS ETRLAVSRVI TWTTEPKSSD
     VRKAAQSVLI SLFELNTPEF TMLLGALPKT FQDGATKLLH NHLRNTGNGT QSSMGSPLTR
     PTPRSPANWS SPLTSPTNTS QNTLSPSAFD YDTENMNSED IYSSLRGVTE AIQNFSFRSQ
     EDMNEPLKRD SKKDDGDSMC GGPGMSDPRA GGDATDLSQT ALDNKASLLH SVPTHSSPRS
     RDYNPYNYSD SISPFNKSAL KEAMFDDDAD QFPDDLSLDH SDLVAELLKE LSNHNERVEE
     RKIALYELMK LTQEESFSVW DEHFKTILLL LLETLGDKEP TIRALALKVL REILRHQPAR
     FKNYAELTVM KTLEAHKDPH KEVVRSAEEA ASVLATSISP EQCIKVLCPI IQTADYPINL
     AAIKMQTKVI ERVSKETLNL LLPEIMPGLI QGYDNSESSV RKACVFCLVA VHAVIGDELK
     PHLSQLTGSK MKLLNLYIKR AQTGSGGADP TTDVSGQS
//