ID   A0A2K5JHE4_COLAP        Unreviewed;       524 AA.
AC   A0A2K5JHE4;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   24-JAN-2024, entry version 28.
DE   RecName: Full=C3H1-type domain-containing protein {ECO:0000259|PROSITE:PS50103};
OS   Colobus angolensis palliatus (Peters' Angolan colobus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Colobinae; Colobus.
OX   NCBI_TaxID=336983 {ECO:0000313|Ensembl:ENSCANP00000028245.1, ECO:0000313|Proteomes:UP000233080};
RN   [1] {ECO:0000313|Ensembl:ENSCANP00000028245.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the CAF1 family.
CC       {ECO:0000256|ARBA:ARBA00008372}.
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DR   AlphaFoldDB; A0A2K5JHE4; -.
DR   STRING; 336983.ENSCANP00000028245; -.
DR   Ensembl; ENSCANT00000051283.1; ENSCANP00000028245.1; ENSCANG00000037540.1.
DR   Proteomes; UP000233080; Unplaced.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0004535; F:poly(A)-specific ribonuclease activity; IEA:UniProt.
DR   Gene3D; 6.10.250.3220; -; 1.
DR   Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR   InterPro; IPR006941; RNase_CAF1.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR036397; RNaseH_sf.
DR   InterPro; IPR000571; Znf_CCCH.
DR   PANTHER; PTHR15092; POLY A -SPECIFIC RIBONUCLEASE/TARGET OF EGR1, MEMBER 1; 1.
DR   PANTHER; PTHR15092:SF37; TARGET OF EGR1 PROTEIN 1; 1.
DR   Pfam; PF04857; CAF1; 2.
DR   Pfam; PF00642; zf-CCCH; 1.
DR   SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR   PROSITE; PS50103; ZF_C3H1; 1.
PE   3: Inferred from homology;
KW   Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233080};
KW   Zinc {ECO:0000256|PROSITE-ProRule:PRU00723};
KW   Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00723}.
FT   DOMAIN          308..336
FT                   /note="C3H1-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50103"
FT   ZN_FING         308..336
FT                   /note="C3H1-type"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00723"
FT   REGION          346..416
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          505..524
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        380..402
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   524 AA;  58182 MW;  B39B24DABFF869D1 CRC64;
     MLRTHRRLRR ETSGVMAAYS DDGAASAPAA SDGGVSKSTS GEELVVRVPV VDVQSNNFKE
     MWPSLLLAIK TANFVAVDTE LSGLGDRKSL LNQCIEERYK AVCHAARTRS ILSLGLACFK
     RQPDKGEHSY LAQVFNLTLL CMEEYVIEPK SVQFLIQHGF NFNQQYAQGI PYHKGNDKGD
     ESQSQSVRTL FLELIRARRP LVLHNGLIDL VFLYQNFYAH LPESLGTFTA DLCEMFPAGI
     YDTKYAAEFH ARFVASYLEY AFRKCERENG KQRAAGSPHL TLEFCNYPSS MRDHIDYRCC
     LPPATHRPHP TSICDNFSAY GWCPLGPQCP QSHDIDLIID TDEAAAEDKR RRRRRREKQK
     RALLNLPGTQ TSGEAKDGPP KKQVCGDSLK AEETEQEVAE NETRNLPHSN QGNKNDLEMG
     VTATRPEIAD TATSEVPGSQ ASSNPVPGDG LHRAGFDAFM TGYVMAYVEV SQGPQPGSSG
     PWLPECHNKV YLSGKAVPLT VAKSQFSRSS KAHNQKMKLA WGSS
//