ID   A0A2K5JIT5_COLAP        Unreviewed;       391 AA.
AC   A0A2K5JIT5;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   24-JAN-2024, entry version 25.
DE   RecName: Full=G-protein coupled receptors family 1 profile domain-containing protein {ECO:0000259|PROSITE:PS50262};
OS   Colobus angolensis palliatus (Peters' Angolan colobus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Colobinae; Colobus.
OX   NCBI_TaxID=336983 {ECO:0000313|Ensembl:ENSCANP00000028755.1, ECO:0000313|Proteomes:UP000233080};
RN   [1] {ECO:0000313|Ensembl:ENSCANP00000028755.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651,
CC       ECO:0000256|RuleBase:RU046427}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004651, ECO:0000256|RuleBase:RU046427}.
CC       Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC       Vasopressin/oxytocin receptor subfamily.
CC       {ECO:0000256|RuleBase:RU046427}.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC       feature annotation. {ECO:0000256|RuleBase:RU046427}.
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DR   AlphaFoldDB; A0A2K5JIT5; -.
DR   STRING; 336983.ENSCANP00000028755; -.
DR   Ensembl; ENSCANT00000051846.1; ENSCANP00000028755.1; ENSCANG00000037843.1.
DR   Proteomes; UP000233080; Unplaced.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008188; F:neuropeptide receptor activity; IEA:InterPro.
DR   GO; GO:0005000; F:vasopressin receptor activity; IEA:InterPro.
DR   CDD; cd15197; 7tmA_NPSR; 1.
DR   Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR   InterPro; IPR000276; GPCR_Rhodpsn.
DR   InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR   InterPro; IPR027294; NPS_rcpt.
DR   InterPro; IPR001817; Vasoprsn_rcpt.
DR   PANTHER; PTHR24244; NEUROPEPTIDE S RECEPTOR; 1.
DR   PANTHER; PTHR24244:SF2; NEUROPEPTIDE S RECEPTOR; 1.
DR   Pfam; PF00001; 7tm_1; 1.
DR   PRINTS; PR00237; GPCRRHODOPSN.
DR   PRINTS; PR00896; VASOPRESSINR.
DR   SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR   PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR   PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE   3: Inferred from homology;
KW   G-protein coupled receptor {ECO:0000256|RuleBase:RU046427};
KW   Glycoprotein {ECO:0000256|RuleBase:RU046427};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU046427};
KW   Receptor {ECO:0000256|RuleBase:RU046427};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233080};
KW   Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|RuleBase:RU046427};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU046427};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU046427}.
FT   TRANSMEM        54..72
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU046427"
FT   TRANSMEM        84..103
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU046427"
FT   TRANSMEM        123..144
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU046427"
FT   TRANSMEM        165..186
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU046427"
FT   TRANSMEM        206..233
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU046427"
FT   TRANSMEM        272..293
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU046427"
FT   DOMAIN          66..330
FT                   /note="G-protein coupled receptors family 1 profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50262"
SQ   SEQUENCE   391 AA;  44621 MW;  B3F607E727837B83 CRC64;
     MPANFTEGSF DSNGTGQMLD SSPVACTETV TFTEVVEGKE WGSFYYSFKT EQLITLWVLF
     VFTIVGNSVV LFSTWRRKRK SRMTFFVTQL AITDSFTGLV NILTDIIWRF TGDFMAPDLV
     CRVVRYLQVV LLYASTYVLV SLSIDRYHAI VYPMKFLQRE KQARVLIVIA WSLSFLFSIP
     TLIIFGKRTL SNGEVQCWAL WPDDSYWTPY MTIVAFLVYF IPLTIISIMY GIVIRTIWIK
     SKTYETVISN CSDGKLCSSY NRGLISKAKI KAIKYSIVII LAFICCWSPY FLFDILDNFN
     LLPDTQERFY ASVIIQNLPA LNSAINPLIY CVFSSSISFP CGANSSVYLL ACDVSVLWAL
     VLTSEKESCE SWRRKGAKIT GFQNDVPREN Q
//