ID   A0A2K5JJ86_COLAP        Unreviewed;       307 AA.
AC   A0A2K5JJ86;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   RecName: Full=Beta-sarcoglycan {ECO:0000256|ARBA:ARBA00015329};
OS   Colobus angolensis palliatus (Peters' Angolan colobus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Colobinae; Colobus.
OX   NCBI_TaxID=336983 {ECO:0000313|Ensembl:ENSCANP00000028943.1, ECO:0000313|Proteomes:UP000233080};
RN   [1] {ECO:0000313|Ensembl:ENSCANP00000028943.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- FUNCTION: Component of the sarcoglycan complex, a subcomplex of the
CC       dystrophin-glycoprotein complex which forms a link between the F-actin
CC       cytoskeleton and the extracellular matrix.
CC       {ECO:0000256|ARBA:ARBA00002860}.
CC   -!- SUBUNIT: Cross-link to form 2 major subcomplexes: one consisting of
CC       SGCB, SGCD and SGCG and the other consisting of SGCB and SGCD. The
CC       association between SGCB and SGCG is particularly strong while SGCA is
CC       loosely associated with the other sarcoglycans.
CC       {ECO:0000256|ARBA:ARBA00026041}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane, sarcolemma
CC       {ECO:0000256|ARBA:ARBA00004274}; Single-pass type II membrane protein
CC       {ECO:0000256|ARBA:ARBA00004274}.
CC   -!- SIMILARITY: Belongs to the sarcoglycan beta/delta/gamma/zeta family.
CC       {ECO:0000256|ARBA:ARBA00007574}.
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DR   AlphaFoldDB; A0A2K5JJ86; -.
DR   Ensembl; ENSCANT00000052050.1; ENSCANP00000028943.1; ENSCANG00000037969.1.
DR   OMA; KGVQGME; -.
DR   Proteomes; UP000233080; Unplaced.
DR   GO; GO:0016012; C:sarcoglycan complex; IEA:InterPro.
DR   GO; GO:0042383; C:sarcolemma; IEA:UniProtKB-SubCell.
DR   GO; GO:0007517; P:muscle organ development; IEA:InterPro.
DR   InterPro; IPR006875; Sarcoglycan.
DR   InterPro; IPR027659; Sgcb.
DR   PANTHER; PTHR21142:SF2; BETA-SARCOGLYCAN; 1.
DR   PANTHER; PTHR21142; SARCOGLYCANS; 1.
DR   Pfam; PF04790; Sarcoglycan_1; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233080};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        53..79
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          1..21
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   307 AA;  33828 MW;  17D87C178BD6EA08 CRC64;
     QSSNGPVKKS MREKAVERRN VNKEHNSNFK AGYIPIDEDR LHKTGLRGRK GNLAICVIIL
     LFILAVINLI ITLVIWAVIR IGPNGCDSME FHESGLLRFK QVSDMGVIHP LYKSTVGGRR
     NENLVITGNN QPIVFQQGTT KLSVENNKTS ITSDIGMQFF DPRTQNILFS TDYETHEFHL
     PSGVKSLNVQ KASTERITSN ATSDLNIKVD GHAIVRGNEG VFIMGKTIEF HMGGNMELKA
     ENSIILNGSV MVSTTRLPSS SSGDQLGSGD WVRYKLCMCA DGTLFKVQVT SQNMGCQISD
     NPCGNTH
//