ID A0A2K5JKP0_COLAP Unreviewed; 1399 AA.
AC A0A2K5JKP0;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=Condensin complex subunit 1 {ECO:0000256|PIRNR:PIRNR017127};
OS Colobus angolensis palliatus (Peters' Angolan colobus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Colobinae; Colobus.
OX NCBI_TaxID=336983 {ECO:0000313|Ensembl:ENSCANP00000029396.1, ECO:0000313|Proteomes:UP000233080};
RN [1] {ECO:0000313|Ensembl:ENSCANP00000029396.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- FUNCTION: Regulatory subunit of the condensin complex, a complex
CC required for conversion of interphase chromatin into mitotic-like
CC condense chromosomes. The condensin complex probably introduces
CC positive supercoils into relaxed DNA in the presence of type I
CC topoisomerases and converts nicked DNA into positive knotted forms in
CC the presence of type II topoisomerases.
CC {ECO:0000256|PIRNR:PIRNR017127}.
CC -!- SUBCELLULAR LOCATION: Chromosome {ECO:0000256|ARBA:ARBA00004286}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the CND1 (condensin subunit 1) family.
CC {ECO:0000256|ARBA:ARBA00009606, ECO:0000256|PIRNR:PIRNR017127}.
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DR RefSeq; XP_011807256.1; XM_011951866.1.
DR RefSeq; XP_011807264.1; XM_011951874.1.
DR STRING; 336983.ENSCANP00000029396; -.
DR Ensembl; ENSCANT00000052549.1; ENSCANP00000029396.1; ENSCANG00000038298.1.
DR GeneID; 105518752; -.
DR KEGG; cang:105518752; -.
DR CTD; 9918; -.
DR OMA; CPLEKLW; -.
DR OrthoDB; 5480287at2759; -.
DR Proteomes; UP000233080; Unplaced.
DR GO; GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0007076; P:mitotic chromosome condensation; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR026971; CND1/NCAPD3.
DR InterPro; IPR032682; Cnd1_C.
DR InterPro; IPR007673; Condensin_cplx_su1.
DR InterPro; IPR024324; Condensin_cplx_su1_N.
DR PANTHER; PTHR14222; CONDENSIN; 1.
DR PANTHER; PTHR14222:SF2; CONDENSIN COMPLEX SUBUNIT 1; 1.
DR Pfam; PF12717; Cnd1; 1.
DR Pfam; PF12922; Cnd1_N; 1.
DR PIRSF; PIRSF017127; Condensin_D2; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306, ECO:0000256|PIRNR:PIRNR017127};
KW Cell division {ECO:0000256|ARBA:ARBA00022618,
KW ECO:0000256|PIRNR:PIRNR017127}; Chromosome {ECO:0000256|ARBA:ARBA00022454};
KW DNA condensation {ECO:0000256|ARBA:ARBA00023067,
KW ECO:0000256|PIRNR:PIRNR017127};
KW Mitosis {ECO:0000256|ARBA:ARBA00022776, ECO:0000256|PIRNR:PIRNR017127};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000233080}.
FT DOMAIN 77..238
FT /note="Condensin complex subunit 1 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF12922"
FT DOMAIN 1068..1229
FT /note="Condensin complex subunit 1 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF12717"
FT REGION 954..982
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1306..1399
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 954..973
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1311..1337
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1399 AA; 156856 MW; 06F28445145ADFD7 CRC64;
MAPQMYEFHL PLSPEELLKS GGVNQYVVQE VLSIKHLPPQ LRAFQAAFRA QGPLAMLEHF
DTIYSILHHF RSIDPGLKED TLEFLIKVVS RHSQELPAVL DDTTLSGSDR NAHLNALKMN
CYALIRLLES FETSQTNLVD LDLGGKGKKA RIKAAHGFDW EEERQPILQL LTQLLQLDIR
HLWKHSIIEE EFVSLVTGCC YRLLENPTIS HQKNRPTRDA ITHLLGVALT RYNHMLSATV
KIIQMLQHFE HLAPVLVAAV SLWATDYGMK SVVGEIVREI GQKCPQELSR DPSGTKGFAA
FLTELAERVP AILMSSMCIL LDHLDGENYM MRNAVLAAMA EMVLQVLNGD QLEAAARDTR
DQFLDTLQAH GHDVNSFVRS RVLQLFTRIV QQKALPLTRF QAVVALAVGR LADKSVLVCK
NAIQLLASFL ANNPFSCKLS DTDLAGPLQK ETQKLQEMRA QRRTAAASAV LDPEEEWEAM
LPELKSTLQQ LLRLPQGEEE IPEQIANTET TEEVKGRIHQ LLAKASYKQA ISLTREATGH
FQESEPFSHI DPEESEETRL LNILGLIFKG PAASTQEKNP QESVGNMVTG QTVCKNKPSA
LAPEESRGSD ELVKQEMLVQ YLQDAYSFSR KMTAAIGITS KMMYENTTTV VQEVIEFFVM
VFQFGVPQAL FGVRRMLPLI WSKEPGVREA VLNAFRQLYL NPKGDSARAK AQALIQNLSL
LLVDASVGTI QCLEEILCEF VRNDELKPAV TQLLWERATE KVACCPLERC SSVMLLGMMA
RGKPEIVGSN LDTLVSIGLD EKLPQDYRLA QQVCHAIANI SDRRKPSLGK RHPPFRLPQE
HRLFERLRET VTKGFVHPDP LWIPFKEVAV TLIYQLAEGP EVICAQILQG CAKQALEKLE
EKRTSQEDPK ESAAMLPTFL LMNLLSLAGD VALQQLVHLE QAVSGELCRR RVLREEQEHK
TKDPKEKNTS SETTMEEELG LAGATADDTE AELIRGICEM ELLDGKQTLA AFVPLLLKVC
NNPGLYSNPD LSAAASLALG KFCMISATFC DSQLRLLFTM LEKSPLPIVR SNLMVATGDL
AIRFPNLVDP WTPHLYARLR DPAQQVRKTA GLVMTHLILK DMVKVKGQVS EMAVLLIDPE
PQIAALAKNF FNELSHKGNA IYNLLPDIIS RLSDPELGVE EEPFHTIMKQ LLSYITKDKQ
TESLVEKLCQ RFRTARTERQ QRDLAYCVSL LPLTERGLRK MLDNFDCFGD KLSDESIFSA
FLSVVGKLRR WAKPESKAVI DEFEQKLRAC HTRGLDGIDE LEIGQAGSQR APSAKKPSTV
SRHQPLASTA SDNDFVTPEP RRTTRRHPNT QQRASKKKPK VVFSSDESSE EDLSAEMTED
ETPRKTTPIL RASARRRRP
//
