ID A0A2K5K1S7_COLAP Unreviewed; 1498 AA.
AC A0A2K5K1S7;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE RecName: Full=FYVE and coiled-coil domain autophagy adaptor 1 {ECO:0008006|Google:ProtNLM};
OS Colobus angolensis palliatus (Peters' Angolan colobus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Colobinae; Colobus.
OX NCBI_TaxID=336983 {ECO:0000313|Ensembl:ENSCANP00000035051.1, ECO:0000313|Proteomes:UP000233080};
RN [1] {ECO:0000313|Ensembl:ENSCANP00000035051.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR RefSeq; XP_011808062.1; XM_011952672.1.
DR STRING; 336983.ENSCANP00000035051; -.
DR Ensembl; ENSCANT00000058287.1; ENSCANP00000035051.1; ENSCANG00000041209.1.
DR GeneID; 105519333; -.
DR KEGG; cang:105519333; -.
DR CTD; 79443; -.
DR OrthoDB; 5394846at2759; -.
DR Proteomes; UP000233080; Unplaced.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd15726; FYVE_FYCO1; 1.
DR CDD; cd17698; RUN_FYCO1; 1.
DR Gene3D; 1.20.58.900; -; 1.
DR Gene3D; 2.60.120.680; GOLD domain; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR047337; FYVE_FYCO1.
DR InterPro; IPR009038; GOLD_dom.
DR InterPro; IPR036598; GOLD_dom_sf.
DR InterPro; IPR004012; Run_dom.
DR InterPro; IPR037213; Run_dom_sf.
DR InterPro; IPR047336; RUN_FYCO1.
DR InterPro; IPR000306; Znf_FYVE.
DR InterPro; IPR017455; Znf_FYVE-rel.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR46753; FYVE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR46753:SF2; FYVE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF01363; FYVE; 1.
DR Pfam; PF02759; RUN; 1.
DR SMART; SM00064; FYVE; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR SUPFAM; SSF140741; RUN domain-like; 1.
DR SUPFAM; SSF101576; Supernatant protein factor (SPF), C-terminal domain; 1.
DR PROSITE; PS50866; GOLD; 1.
DR PROSITE; PS50826; RUN; 1.
DR PROSITE; PS50178; ZF_FYVE; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000233080};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00091}.
FT DOMAIN 36..169
FT /note="RUN"
FT /evidence="ECO:0000259|PROSITE:PS50826"
FT DOMAIN 1173..1231
FT /note="FYVE-type"
FT /evidence="ECO:0000259|PROSITE:PS50178"
FT DOMAIN 1357..1486
FT /note="GOLD"
FT /evidence="ECO:0000259|PROSITE:PS50866"
FT REGION 584..615
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1231..1277
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 225..273
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 400..441
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 473..556
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1081..1147
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 586..615
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1233..1250
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1498 AA; 168840 MW; 3A89049B465895B8 CRC64;
MASTNAESQL QRIIRDLQDA VTELSKEFQE AGEPITDDST SLHKFSYKLE YLLQFDQKEK
ATLLGNKKDY WDYFCACLAK VKGANDGIRF VKSISELRTS LGKGRAFIRY SLVHQRLADT
LQQCFMNTKV TSDWYYSRSP FLQPKLSSDI VGQLYELTEV QFDLASRGYD LDAAWPTFAR
RTLATGSSAY LWKPPSRSSS MSSLVSSYLQ TQEMVSNFDL NSPLNNEALE GFDEMRLELD
QLEVREKQLQ ERIQQLDREN QELRAAVSLQ GEQLQTERER GRTAAEDNVR LTCLVAELQK
QWEVTQATQN TVKELQTCLQ ALELGAAEKE EDYHTALRQL ESMLQPLAQE LKATWDPLGK
KNQHLASIPD WLVMAQQKAD TAPDTKGQQE PIPSDAAQEI QELGEKLRTL ERERTKVEEV
NRQQSAQLEQ LVKELQLKED AWASLEHLVK EMAPLQEELS GKGQEADQLW RRLQELLVHS
SSREQELAEL RREKKQQQEE KELLEQEVRS LTRQLQFLET QLAQVSQHVS DLEEQKKQLI
QDKDHLSQKV GALERLAGQP SPELPVAGGK NEALVPVNSS LQEACGKPEE EQRGPQEAQL
DDTKVQEGSQ EEELRQANRE LEKELQNVVG RNQLLEGKLQ ALQADYQALQ QREAAIQGSL
ASLEAEQASI RHLGDQMEAS LLAVRKAKEA MKAKVAEKEA TLQSKEDECQ QLREEVEQCR
QLAEARHREL RALESQCQQQ TQLIEVLTAE KGQQGVGPPP DDEARELAAQ LALSQAQLEV
HQGEAQRLQA QVVDLQAKMR AALDDQDKMQ SQLSMAEAVL REHKTLVQQL KEQNEALNRA
HVQELLQCSE REGALQEERT SEAQQREEEL RALQEELSQA KCSSEEAHLE HAELQEQLHR
ANTDTAELGI QVCTLTMEKE QVEKALASAV QELQDAKEAA SREREGLERQ VAGLQQEKES
LQEKLKVAQA AADSLPGLQA QLTQAEQRAQ SLQEAAHQEL DTLKFQLSAE IMDYQSRLKN
AGEESRSLRG QLEEQGRQLQ AAEEAVGKLK ATQADMGEKL SCTSNHLAEC QAAMLRKDKE
GAALREDLER TQKELEKAAT KIQEYYNKLC EEVTNRERSD QKMLADLDDL NRTKKYLEER
LIELLRDKDA LWQKSDALEF QQKLSAEDRW LGDTEANHCL DCKREFSWMM RRHHCRICGR
IFCYYCCNNY VLSKHSGKKE RCCRACFQKL SEGPGSPDST GSGTSQGEPS PAPSPASPGP
QATGGQGANT DYRPPDDAVF DIITDEELCQ IQESGSSLPE TPTETDSLDP NVAEQASAGA
SKGLGNLLCE SSAYRDTTST SLTPEDTEDM PVGQDAEICL LKSGELMIKV PLTVDEIASF
GEGSRELFVR SSTYSLIPIT VAEAGLTISW VFSSDPKSIS FSVVFQEAED TPLDQCKVLI
PTTRCNSHKE NIQGQLKVRT PGIYMLIFDN TFSRFVSKKV FYHLTVDRPV IYDGSDFL
//
