ID A0A2K5KAT6_COLAP Unreviewed; 701 AA.
AC A0A2K5KAT6;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=SEFIR domain-containing protein {ECO:0000259|PROSITE:PS51534};
OS Colobus angolensis palliatus (Peters' Angolan colobus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Colobinae; Colobus.
OX NCBI_TaxID=336983 {ECO:0000313|Ensembl:ENSCANP00000038202.1, ECO:0000313|Proteomes:UP000233080};
RN [1] {ECO:0000313|Ensembl:ENSCANP00000038202.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_011807657.1; XM_011952267.1.
DR AlphaFoldDB; A0A2K5KAT6; -.
DR Ensembl; ENSCANT00000061458.1; ENSCANP00000038202.1; ENSCANG00000042784.1.
DR GeneID; 105519072; -.
DR CTD; 84818; -.
DR OMA; GHPNICV; -.
DR OrthoDB; 5309006at2759; -.
DR Proteomes; UP000233080; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0030368; F:interleukin-17 receptor activity; IEA:InterPro.
DR GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.11530; -; 1.
DR InterPro; IPR039465; IL-17_rcpt-like.
DR InterPro; IPR027841; IL-17_rcpt_C/E_N.
DR InterPro; IPR013568; SEFIR_dom.
DR PANTHER; PTHR15583; INTERLEUKIN-17 RECEPTOR; 1.
DR PANTHER; PTHR15583:SF12; INTERLEUKIN-17 RECEPTOR C; 1.
DR Pfam; PF15037; IL17_R_N; 1.
DR Pfam; PF08357; SEFIR; 1.
DR PROSITE; PS51534; SEFIR; 1.
PE 4: Predicted;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Inflammatory response {ECO:0000256|ARBA:ARBA00023198};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000233080};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..701
FT /note="SEFIR domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014393938"
FT TRANSMEM 453..473
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 497..649
FT /note="SEFIR"
FT /evidence="ECO:0000259|PROSITE:PS51534"
FT REGION 650..701
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 701 AA; 77083 MW; 496C463752AB7A77 CRC64;
MPVPWFLLSL ALGRSPIVLS LERLVGPQDA THCSPGLSCH LWDSDILCLP GDIVPASGPV
LAPTHLQTEL VLRCRKETYC DLCVRVAVHL AVHGHWEEPE DEEKFGGAAD PGVEEPRNAS
LQAQVVLSFQ AYPTTRCVLL EVQVPAALVQ FGQSVGSVVY DCFEAALGSE VRIWSYTQPR
YEKELNLTQQ LPALPWLNVS ADGDNVHLIL NVSEEQHFGL SLYWNQVQGP PKPRWHKNLT
GPQIITLNHT DLVPCLCIQV WPLEPDSVRT NICPFREDPR AHQNLWRAAR LRLLTLQSWL
LDAPCSLPAE AALCWQAPGG DPCQPLVPPL SWENVTVDKV LEFPLLKGHP NLCVQVNSWE
QLQLQECLWA DSLGPLKDDV LLLETRGPQD NRSLCALEPS GCTSLPSKAS TRAARLGEYL
LQDLQSGQCL QLWDDDLGAL WACSMDKYIH KRWALLWLAC LLFAAALSLI LLLKKDHAKG
WLRLLKQDVR SGAAARGRAA LLLYSADDSG FERLVGALAS ALCQLPLRVA VDLWSRREMS
AQGPVAWFHA QRRQTLQEGG VVVLLFSPGA VALCSEWLQD GVSAPGAHGP HDAFRASLSC
VLPDFLQGQA PGRYVGACFD RLLHPDSVPA LFRTVPVFSL PSQLPDFLGA LQQPRTPRPR
RLQERAEQVS RALQPALDSY FHPPGTPAPG RGVGPGAGDG T
//
