ID   A0A2K5KGL8_COLAP        Unreviewed;       749 AA.
AC   A0A2K5KGL8;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   RecName: Full=Semaphorin 3B {ECO:0008006|Google:ProtNLM};
OS   Colobus angolensis palliatus (Peters' Angolan colobus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Colobinae; Colobus.
OX   NCBI_TaxID=336983 {ECO:0000313|Ensembl:ENSCANP00000040237.1, ECO:0000313|Proteomes:UP000233080};
RN   [1] {ECO:0000313|Ensembl:ENSCANP00000040237.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the semaphorin family.
CC       {ECO:0000256|ARBA:ARBA00009492}.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC       feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00352}.
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DR   RefSeq; XP_011794428.1; XM_011939038.1.
DR   AlphaFoldDB; A0A2K5KGL8; -.
DR   STRING; 336983.ENSCANP00000040237; -.
DR   Ensembl; ENSCANT00000063501.1; ENSCANP00000040237.1; ENSCANG00000043793.1.
DR   GeneID; 105509679; -.
DR   KEGG; cang:105509679; -.
DR   CTD; 7869; -.
DR   OMA; ISLHRCA; -.
DR   OrthoDB; 5342713at2759; -.
DR   Proteomes; UP000233080; Unplaced.
DR   GO; GO:0030215; F:semaphorin receptor binding; IEA:InterPro.
DR   GO; GO:0016043; P:cellular component organization; IEA:UniProt.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR   Gene3D; 3.30.1680.10; ligand-binding face of the semaphorins, domain 2; 1.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR013151; Immunoglobulin.
DR   InterPro; IPR016201; PSI.
DR   InterPro; IPR001627; Semap_dom.
DR   InterPro; IPR036352; Semap_dom_sf.
DR   InterPro; IPR027231; Semaphorin.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   PANTHER; PTHR11036; SEMAPHORIN; 1.
DR   PANTHER; PTHR11036:SF37; SEMAPHORIN-3B; 1.
DR   Pfam; PF00047; ig; 1.
DR   Pfam; PF01403; Sema; 1.
DR   SMART; SM00409; IG; 1.
DR   SMART; SM00423; PSI; 1.
DR   SMART; SM00630; Sema; 1.
DR   SUPFAM; SSF48726; Immunoglobulin; 1.
DR   SUPFAM; SSF103575; Plexin repeat; 1.
DR   SUPFAM; SSF101912; Sema domain; 1.
DR   PROSITE; PS50835; IG_LIKE; 1.
DR   PROSITE; PS51004; SEMA; 1.
PE   3: Inferred from homology;
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233080};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           25..749
FT                   /note="Semaphorin 3B"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5014472425"
FT   DOMAIN          30..513
FT                   /note="Sema"
FT                   /evidence="ECO:0000259|PROSITE:PS51004"
FT   DOMAIN          573..659
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50835"
FT   REGION          701..749
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        733..749
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   749 AA;  82994 MW;  A4506EC6B8A6679F CRC64;
     MGRAGAAAMI PGLALLWAVG LGGAVPSPPR LRLSFQELQA WHGLQTFSLE RTCCYEALLV
     DEERGRLFVG AENHVASLSL DNISKRAKKL AWPAPVEWRE ECNWAGKDIG TECMNFVKLL
     HAYNRTHLLA CGTGAFHPTC AFVEVGHRAE EPVLRLDPGS IEDGKGKSPY DPRHRAASVL
     VGEELYSGVA ADLMGRDFTI FRSLGQRPSL RTEPHDSRWL NEPKFVKVFW IPESENPDDD
     KIYFFFRETA VEAAPALGRL SVSRVGQICR NDVGGQRSLV NKWTTFLKAR LVCSVPGVEG
     DTHFDQLQDV FLLSSRDHRT PLLYAVFSTS SSIFQGSAVC VYSMNDVRRA FLGPFAHKEG
     PMHQWVSYQG RVPYPRPGMC PSKTFGTFSS TKDFPDDVIQ FARNHPLMYN SVLPLGGRPL
     FLQVGANYTF THIATDRVAA ADGHYDVLFI GTDAGTVLKV ISVPKGSRPS AEGLLLEELH
     VFEDSAAVTS MQISSKRHQL YIASRSAVAQ IALHRCAAHG RVCAECCLAR DPYCAWDGVA
     CTRFQPSVKR RFRRQDVRNG DPSTLCSGDS SRPALLEHKV FGVEGSSAFL ECEPRSLQAR
     VEWTFQRAGL TTHTQVLAQE RTERTARGLL LRRLRRRDSG VYLCAAVEQG FTQPLRRLSL
     HVLSATQAER LAGAEEAAPA APPGPKLWYR DFLQLVEPGG GGSANSLRMC RPQPALQSLA
     PESRRKGRNR RTHAPEPRAE RGPRSATHW
//