ID A0A2K5KKA0_CERAT Unreviewed; 635 AA.
AC A0A2K5KKA0;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Ankyrin repeat and SOCS box containing 2 {ECO:0000313|Ensembl:ENSCATP00000001110.1};
GN Name=ASB2 {ECO:0000313|Ensembl:ENSCATP00000001110.1};
OS Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Cercocebus.
OX NCBI_TaxID=9531 {ECO:0000313|Ensembl:ENSCATP00000001110.1, ECO:0000313|Proteomes:UP000233060};
RN [1] {ECO:0000313|Ensembl:ENSCATP00000001110.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC -!- SIMILARITY: Belongs to the ankyrin SOCS box (ASB) family.
CC {ECO:0000256|ARBA:ARBA00005949}.
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DR RefSeq; XP_011939174.1; XM_012083784.1.
DR RefSeq; XP_011939175.1; XM_012083785.1.
DR AlphaFoldDB; A0A2K5KKA0; -.
DR Ensembl; ENSCATT00000005975.1; ENSCATP00000001110.1; ENSCATG00000005191.1.
DR GeneID; 105596609; -.
DR KEGG; caty:105596609; -.
DR CTD; 51676; -.
DR GeneTree; ENSGT00940000155490; -.
DR OrthoDB; 5474869at2759; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000233060; Unplaced.
DR Bgee; ENSCATG00000005191; Expressed in heart and 5 other cell types or tissues.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR CDD; cd03721; SOCS_ASB2; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 3.
DR Gene3D; 1.10.750.20; SOCS box; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR037330; ASB2_SOCS.
DR InterPro; IPR001496; SOCS_box.
DR InterPro; IPR036036; SOCS_box-like_dom_sf.
DR PANTHER; PTHR24178:SF9; ANK_REP_REGION DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR24178; MOLTING PROTEIN MLT-4; 1.
DR Pfam; PF12796; Ank_2; 3.
DR Pfam; PF13606; Ank_3; 1.
DR Pfam; PF13637; Ank_4; 1.
DR Pfam; PF07525; SOCS_box; 1.
DR PRINTS; PR01415; ANKYRIN.
DR SMART; SM00248; ANK; 11.
DR SMART; SM00253; SOCS; 1.
DR SMART; SM00969; SOCS_box; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF158235; SOCS box-like; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 8.
DR PROSITE; PS50088; ANK_REPEAT; 9.
DR PROSITE; PS50225; SOCS; 1.
PE 3: Inferred from homology;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Reference proteome {ECO:0000313|Proteomes:UP000233060}.
FT REPEAT 171..203
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 204..236
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 237..269
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 270..302
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 303..335
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 336..368
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 368..400
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 410..438
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 440..472
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 586..635
FT /note="SOCS box"
FT /evidence="ECO:0000259|PROSITE:PS50225"
SQ SEQUENCE 635 AA; 70223 MW; 9BE2B3502DC4C950 CRC64;
MATQISTRGS QCTIGQEEYS LYSSLSEEEL VQMAIEQSLA DKTRGPTTAE ATVSACANRQ
PAHFYPWTRS TAPPESSPAR APMGLFQGVM QKYSSSLFQT SQLAPVDPLI KAIKNGDEEA
LKTMIKEGKN LAEPNKEGWL PLHEAAYYGQ LGCLKVLQRA YPGTIDQRTL QEETAVYLAT
CRGHLDCLLS LLQAGAEPDI SNKSRETPLY KACEHKNAEA VKILVQHNAD TNHRCNRGWT
ALHESVSRND LEVMEILVNG GAKVESKNAY GITPLFVAAQ SGQLEALRFL AKYGADINTQ
ASDSASALYE ACKNEHEEVV EFLLLQGADA NKTNKDGLLP LHIASKKGNY RIVQMLLPVT
SRTRVRRSGV SPLHLAAERN NDAVLEALLS ARFDVNAPLA PERARLYEDR RSSALYFAVV
NNNVYATELL LEHGADPNRD VISPLLVAIR HGCLRTMQLL LDHGANIDAY IATHPTAFPA
TIMFAMKCLS LLKFLMDLGC DGEPCFSCLY GNGPHPPAPQ PSSRFNDTPV SDKEPSVVQF
CEFVSAPEVS RWAGPIIDVL LDYVGNVQLC SRLKEHIDSF EDWAVIKEKA EPPRPLAHLC
RLRVRKAIGK YRIKLLDTLP LPGRLIRYLK YENTQ
//
