ID A0A2K5KMT1_CERAT Unreviewed; 648 AA.
AC A0A2K5KMT1;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Zinc finger protein 595 {ECO:0000313|Ensembl:ENSCATP00000002001.1};
GN Name=ZNF595 {ECO:0000313|Ensembl:ENSCATP00000002001.1};
OS Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Cercocebus.
OX NCBI_TaxID=9531 {ECO:0000313|Ensembl:ENSCATP00000002001.1, ECO:0000313|Proteomes:UP000233060};
RN [1] {ECO:0000313|Ensembl:ENSCATP00000002001.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- FUNCTION: May be involved in transcriptional regulation.
CC {ECO:0000256|ARBA:ARBA00003767}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the krueppel C2H2-type zinc-finger protein
CC family. {ECO:0000256|ARBA:ARBA00006991}.
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DR RefSeq; XP_011914740.1; XM_012059350.1.
DR Ensembl; ENSCATT00000010073.1; ENSCATP00000002001.1; ENSCATG00000009108.1.
DR Ensembl; ENSCATT00000010121.1; ENSCATP00000002017.1; ENSCATG00000009108.1.
DR GeneID; 105585520; -.
DR KEGG; caty:105585520; -.
DR GeneTree; ENSGT00940000161765; -.
DR OrthoDB; 5398495at2759; -.
DR Proteomes; UP000233060; Unplaced.
DR Bgee; ENSCATG00000009108; Expressed in skeletal muscle tissue and 12 other cell types or tissues.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd07765; KRAB_A-box; 1.
DR Gene3D; 6.10.140.140; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 18.
DR InterPro; IPR001909; KRAB.
DR InterPro; IPR036051; KRAB_dom_sf.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR14003:SF23; GENE 12845-RELATED; 1.
DR PANTHER; PTHR14003; TRANSCRIPTIONAL REPRESSOR PROTEIN YY; 1.
DR Pfam; PF01352; KRAB; 1.
DR Pfam; PF00096; zf-C2H2; 16.
DR SMART; SM00349; KRAB; 1.
DR SMART; SM00355; ZnF_C2H2; 18.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 10.
DR SUPFAM; SSF109640; KRAB domain (Kruppel-associated box); 1.
DR PROSITE; PS50805; KRAB; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 17.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 18.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000233060};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00042}.
FT DOMAIN 4..75
FT /note="KRAB"
FT /evidence="ECO:0000259|PROSITE:PS50805"
FT DOMAIN 145..172
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 173..199
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 200..227
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 228..255
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 256..283
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 284..311
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 312..339
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 340..367
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 368..395
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 396..423
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 424..451
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 452..479
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 480..507
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 508..535
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 536..563
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 564..591
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 592..619
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 620..647
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
SQ SEQUENCE 648 AA; 74445 MW; 39B30032ABB811E7 CRC64;
MELLTFRDVA IEFSPEEWKC LDPAQQNLYK DVMLENYRNL VSLGFVISNP DLVTCLEQIK
EPYNLKLHET AAKPPAMCSP FSQDLSPVQG IEDSFQKLVL RRYEKCGYEN LQLRKGCKHV
NECKVQKGVN SGVYQCLSTT QSKIFQCNTC VKVFSKLSNS NKHKTRHTGE KPFTCTECGR
SFYMSHLIDH TGIHAGEKPY KCEKCSKAFN RSTSLTKHKR IHTGEKPYTC EECGKAFRRS
TVLNEHKKIH TGEKPYKCEE CGKAFTRSTT LNEHKKIHTG EKPYKCKECG KTFRWSTSLN
EHKNIHTGEK PYKCEECGKA FRQSRSLNEH KNIHTGEKPY SCEKCGKAFN QSSSLIIHRS
IHSEQKLYKC EECGKAFTWS SSLNKHKRIH TGEKPYTCEE CGKAFYRSSH LAKHKRIHTG
EKPYPCEECG KAFNQSSTLI LHKRIHSGQK PYKCEECGKA FTRSTTLNEH KKIHTGEKPY
KCEECGKAFI WSASLNEHKN IHTGEKPYKC KECGKAFNQS SGLIIHRSIH SEQKLYKCEE
CGKAFTRSTA LNEHKKIHSG EKPYKCKECG KAYNLSSTLT KHRRIHTGEK PFTCEECGKA
FNWSSSLTKH KIIHTGEKFY KCEQCGKAFH RPSTLTVHKR IHTGEEHS
//
