ID A0A2K5KVV1_CERAT Unreviewed; 354 AA.
AC A0A2K5KVV1;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE RecName: Full=protein-tyrosine-phosphatase {ECO:0000256|ARBA:ARBA00013064};
DE EC=3.1.3.48 {ECO:0000256|ARBA:ARBA00013064};
GN Name=PTPN5 {ECO:0000313|Ensembl:ENSCATP00000004829.1};
OS Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Cercocebus.
OX NCBI_TaxID=9531 {ECO:0000313|Ensembl:ENSCATP00000004829.1, ECO:0000313|Proteomes:UP000233060};
RN [1] {ECO:0000313|Ensembl:ENSCATP00000004829.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A2K5KVV1; -.
DR Ensembl; ENSCATT00000018818.1; ENSCATP00000004829.1; ENSCATG00000015959.1.
DR GeneTree; ENSGT00940000159916; -.
DR Proteomes; UP000233060; Unplaced.
DR Bgee; ENSCATG00000015959; Expressed in frontal cortex and 3 other cell types or tissues.
DR GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:UniProtKB-EC.
DR Gene3D; 3.90.190.10; Protein tyrosine phosphatase superfamily; 1.
DR InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR InterPro; IPR000242; PTP_cat.
DR InterPro; IPR008356; Tyr_Pase_KIM-con.
DR PANTHER; PTHR46198; PROTEIN-TYROSINE-PHOSPHATASE; 1.
DR PANTHER; PTHR46198:SF1; TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 5; 1.
DR Pfam; PF00102; Y_phosphatase; 1.
DR PRINTS; PR01778; KIMPTPASE.
DR PRINTS; PR00700; PRTYPHPHTASE.
DR SMART; SM00194; PTPc; 1.
DR SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 1.
DR PROSITE; PS50055; TYR_PHOSPHATASE_PTP; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000233060};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..354
FT /note="protein-tyrosine-phosphatase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014323237"
FT DOMAIN 148..323
FT /note="Tyrosine-protein phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS50055"
FT REGION 16..37
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 312..342
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 316..330
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 354 AA; 40327 MW; 8F2C138CDC317E7F CRC64;
MGLVLVTTLV WHLLRTPPEP PTPLPPEDRR QSVSRQPSFT YSEWMEEKVE DDFLDLDPVP
ETPVFDCVMD IKPEADPASL TVKSMGLQER RGSNVSLTLD MCTPGCNEEG FGYLMSPREE
SAREYLLSAS RVLQAEELHE KALDPFLLQA EFFEIPMNFV DPKEYDIPGL VRKNRYKTIL
PNPHSRVCLT SPDPDDPLSS YINANYIRGY GGEEKVYIAT QGPIVSTVAD FWRMVWQEHT
PIIVMITNIE EMNEKCTEYW PEEQVVYDDV EITVQKVIHT EDYRLRLISL KSGTEERGLK
HYWFTSWWRR QPSRRGPTVP PSSSTAVQGL GGPAASLPPA SAASSCGRRV WWTS
//
