ID A0A2K5KYG2_CERAT Unreviewed; 734 AA.
AC A0A2K5KYG2;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE SubName: Full=NHL repeat containing 2 {ECO:0000313|Ensembl:ENSCATP00000005737.1};
GN Name=NHLRC2 {ECO:0000313|Ensembl:ENSCATP00000005737.1};
OS Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Cercocebus.
OX NCBI_TaxID=9531 {ECO:0000313|Ensembl:ENSCATP00000005737.1, ECO:0000313|Proteomes:UP000233060};
RN [1] {ECO:0000313|Ensembl:ENSCATP00000005737.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR RefSeq; XP_011898367.1; XM_012042977.1.
DR AlphaFoldDB; A0A2K5KYG2; -.
DR STRING; 9531.ENSCATP00000005737; -.
DR Ensembl; ENSCATT00000021207.1; ENSCATP00000005737.1; ENSCATG00000018452.1.
DR GeneID; 105577916; -.
DR KEGG; caty:105577916; -.
DR CTD; 374354; -.
DR GeneTree; ENSGT00390000015483; -.
DR OMA; IAMAGVH; -.
DR OrthoDB; 5475197at2759; -.
DR Proteomes; UP000233060; Unplaced.
DR Bgee; ENSCATG00000018452; Expressed in bone marrow and 12 other cell types or tissues.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR CDD; cd14951; NHL-2_like; 1.
DR CDD; cd03012; TlpA_like_DipZ_like; 1.
DR Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR Gene3D; 2.120.10.30; TolB, C-terminal domain; 2.
DR InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR InterPro; IPR045302; NHL2_NHL_rpt_dom.
DR InterPro; IPR001258; NHL_repeat.
DR InterPro; IPR012336; Thioredoxin-like_fold.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR InterPro; IPR013766; Thioredoxin_domain.
DR PANTHER; PTHR46388; NHL REPEAT-CONTAINING PROTEIN 2; 1.
DR PANTHER; PTHR46388:SF2; NHL REPEAT-CONTAINING PROTEIN 2; 1.
DR Pfam; PF01436; NHL; 4.
DR Pfam; PF13905; Thioredoxin_8; 1.
DR SUPFAM; SSF101898; NHL repeat; 1.
DR SUPFAM; SSF52833; Thioredoxin-like; 1.
DR PROSITE; PS51125; NHL; 1.
DR PROSITE; PS51352; THIOREDOXIN_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000233060};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 43..200
FT /note="Thioredoxin"
FT /evidence="ECO:0000259|PROSITE:PS51352"
FT REPEAT 465..505
FT /note="NHL"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00504"
SQ SEQUENCE 734 AA; 80555 MW; 6F4A3704B2223D84 CRC64;
MAAPGSRGRS LSGLLPAQTS LEYALLDAVT QQEKDSLVYQ YLQKVDGWEQ DLSVPDFPEG
LEWLNTEEPI SVYKDLCGKI VILDFFTYCC MNCIHLLPDL RALEHTYSDK DGLLIIGVHS
AKFPNEKVLD NIKSAVLRYN ITHPVVNDAD ASLWQELEVS CWPTLVILGP RGNMLFSLIG
EGHKDKLFLY TSIALKYYKD RGQIRDDKIG IKLYKDSLPP SPLLFPGKVT VDQVTNRLVI
ADTGHHRILV VWKNGQIQYS IGGPNPGRKD GIFSESTFNS PQGVAIMNNI IYVADTENHL
IRKIDLEAER VSTVAGIGIQ GTDKEGGAKG EQQPISSPWD VVFGTSGSEV QRGDILWIAM
AGTHQIWALL LDSGKLPKKN ELTKGTCLRF AGSGNEENRN NAYPHKAGFA QPSGLSLASE
DPWSCLFVAD SESSTVRTIS LKDGAVKHLV GGERDPMNLF AFGDVDGVGI NAKLQHPLGV
TWDKKRNLLY VADSYNHKIK VVDPKTKNCT TLAGTGDTNN VTSSSFTEST FNEPGGLCIG
ENGQLLYVAD TNNHQIKIMD LETKMVSVLP IFRSENAVVD GPFLVEKQKT LPKLPKSAPS
IRLSPVTVCA GQTLQFKLRL DLPSGSKLTE GAPSCWFLRA EGNEWLLQGQ MPSGDIENIS
SQPTISLQIP DDCLSLEAIV SVSVFLYYCS ADSSACMMKA ILFSQPLQIT DTQQGCIAPV
ELRLLFGDFF KCMC
//
