ID A0A2K5KYS5_CERAT Unreviewed; 351 AA.
AC A0A2K5KYS5;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE RecName: Full=RNA binding protein fox-1 homolog 3 {ECO:0000256|PIRNR:PIRNR037932};
GN Name=RBFOX3 {ECO:0000313|Ensembl:ENSCATP00000005852.1};
OS Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Cercocebus.
OX NCBI_TaxID=9531 {ECO:0000313|Ensembl:ENSCATP00000005852.1, ECO:0000313|Proteomes:UP000233060};
RN [1] {ECO:0000313|Ensembl:ENSCATP00000005852.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- FUNCTION: RNA-binding protein that regulates alternative splicing
CC events. {ECO:0000256|PIRNR:PIRNR037932}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PIRNR:PIRNR037932}.
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DR AlphaFoldDB; A0A2K5KYS5; -.
DR Ensembl; ENSCATT00000021470.1; ENSCATP00000005852.1; ENSCATG00000018349.1.
DR GeneTree; ENSGT00940000159924; -.
DR Proteomes; UP000233060; Unplaced.
DR Bgee; ENSCATG00000018349; Expressed in cerebellum and 1 other cell type or tissue.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR GO; GO:0007399; P:nervous system development; IEA:InterPro.
DR GO; GO:0000381; P:regulation of alternative mRNA splicing, via spliceosome; IEA:InterPro.
DR GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR Gene3D; 3.30.70.330; -; 1.
DR InterPro; IPR025670; Fox-1_C_dom.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR017325; RBFOX1-3.
DR InterPro; IPR047131; RBFOX1-like.
DR InterPro; IPR000504; RRM_dom.
DR PANTHER; PTHR15597; ATAXIN 2-BINDING PROTEIN 1-RELATED; 1.
DR PANTHER; PTHR15597:SF25; RNA BINDING PROTEIN FOX-1 HOMOLOG 3; 1.
DR Pfam; PF12414; Fox-1_C; 1.
DR Pfam; PF00076; RRM_1; 1.
DR PIRSF; PIRSF037932; Ataxin_2_bd_A2BP; 2.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR PROSITE; PS50102; RRM; 1.
PE 4: Predicted;
KW mRNA processing {ECO:0000256|PIRNR:PIRNR037932};
KW mRNA splicing {ECO:0000256|ARBA:ARBA00023187,
KW ECO:0000256|PIRNR:PIRNR037932}; Nucleus {ECO:0000256|PIRNR:PIRNR037932};
KW Reference proteome {ECO:0000313|Proteomes:UP000233060};
KW RNA-binding {ECO:0000256|PIRNR:PIRNR037932, ECO:0000256|PROSITE-
KW ProRule:PRU00176}.
FT DOMAIN 99..136
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 1..106
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..33
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 34..92
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 351 AA; 37687 MW; AE410A916CEC40C4 CRC64;
MAQPYPPAQY PPPPQNGIPA EYAPPPPHPT QDYSGQTPVP SEHGMTLYTP AQTHPEQPGS
EASTQPIAGT QTVPQTDEAA QTDSQPLHPS DPTEKQQPKR LHVSNIPFRF RDPDLRQMFG
QFGKILDVEI IFNERGSKVN NATARVMTNK KTGNPYTNGW KLNPVVGAVY GPEFYAVTGF
PYPTTGTAVA YRGAHLRGRG RAVYNTFRAA PPPPPIPTYG AALEQTLVKM PVPWAGLAPC
PLPPQQTPEP AYPTSPAFPP LSCPFASRVV YQDGFYGAEI YVSAAPPGGR EGSGVLYGRV
YAAADPYHHT IGPAATYSIG TMVRSPGPAL GASPNSWGDG WRGPWGRGRA L
//
