ID   A0A2K5KZ43_CERAT        Unreviewed;       181 AA.
AC   A0A2K5KZ43;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   RecName: Full=Troponin I, fast skeletal muscle {ECO:0000256|ARBA:ARBA00039349};
DE   AltName: Full=Troponin I, fast-twitch isoform {ECO:0000256|ARBA:ARBA00042462};
GN   Name=TNNI2 {ECO:0000313|Ensembl:ENSCATP00000005959.1};
OS   Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Cercocebus.
OX   NCBI_TaxID=9531 {ECO:0000313|Ensembl:ENSCATP00000005959.1, ECO:0000313|Proteomes:UP000233060};
RN   [1] {ECO:0000313|Ensembl:ENSCATP00000005959.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- FUNCTION: Troponin I is the inhibitory subunit of troponin, the thin
CC       filament regulatory complex which confers calcium-sensitivity to
CC       striated muscle actomyosin ATPase activity.
CC       {ECO:0000256|ARBA:ARBA00001988}.
CC   -!- SUBUNIT: Binds to actin and tropomyosin.
CC       {ECO:0000256|ARBA:ARBA00038767}.
CC   -!- SIMILARITY: Belongs to the troponin I family.
CC       {ECO:0000256|ARBA:ARBA00009930}.
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DR   AlphaFoldDB; A0A2K5KZ43; -.
DR   Ensembl; ENSCATT00000021733.1; ENSCATP00000005959.1; ENSCATG00000018216.1.
DR   GeneTree; ENSGT01030000234588; -.
DR   Proteomes; UP000233060; Unplaced.
DR   Bgee; ENSCATG00000018216; Expressed in skeletal muscle tissue and 9 other cell types or tissues.
DR   GO; GO:0005861; C:troponin complex; IEA:InterPro.
DR   GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.5.350; -; 1.
DR   Gene3D; 6.10.250.180; -; 1.
DR   InterPro; IPR001978; Troponin.
DR   InterPro; IPR038077; Troponin_sf.
DR   PANTHER; PTHR13738; TROPONIN I; 1.
DR   PANTHER; PTHR13738:SF15; TROPONIN I, FAST SKELETAL MUSCLE; 1.
DR   Pfam; PF00992; Troponin; 1.
DR   SUPFAM; SSF90250; Troponin coil-coiled subunits; 1.
PE   3: Inferred from homology;
KW   Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW   Muscle protein {ECO:0000256|ARBA:ARBA00023179};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233060}.
FT   REGION          29..50
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        29..43
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   181 AA;  21204 MW;  C7324A6C3CCD6900 CRC64;
     EAPKKRNRAI TARRQHLKSV MLQIAATELE KEESRREAEK QNYLSEHCPP LHIPGSMSEV
     QELCKQLHAK IDAAEEEKYD MEVRVQKSSK ELEDMNQKLF DLRGKFKRPP LRRVRMSADA
     MLKALLGSKH KVCMDLRANL KQVKKEDTEK ERDLRDVGDW RKNIEEKSGM EGRKKMFESE
     S
//