ID   A0A2K5L089_CERAT        Unreviewed;       707 AA.
AC   A0A2K5L089;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 30.
DE   SubName: Full=COP1 E3 ubiquitin ligase {ECO:0000313|Ensembl:ENSCATP00000006356.1};
GN   Name=COP1 {ECO:0000313|Ensembl:ENSCATP00000006356.1};
OS   Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Cercocebus.
OX   NCBI_TaxID=9531 {ECO:0000313|Ensembl:ENSCATP00000006356.1, ECO:0000313|Proteomes:UP000233060};
RN   [1] {ECO:0000313|Ensembl:ENSCATP00000006356.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   RefSeq; XP_011941385.1; XM_012085995.1.
DR   AlphaFoldDB; A0A2K5L089; -.
DR   Ensembl; ENSCATT00000022965.1; ENSCATP00000006356.1; ENSCATG00000017809.1.
DR   GeneID; 105597590; -.
DR   CTD; 64326; -.
DR   GeneTree; ENSGT00920000149161; -.
DR   OrthoDB; 1126684at2759; -.
DR   Proteomes; UP000233060; Unplaced.
DR   Bgee; ENSCATG00000017809; Expressed in colon and 12 other cell types or tissues.
DR   GO; GO:0043229; C:intracellular organelle; IEA:UniProt.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0061630; F:ubiquitin protein ligase activity; IEA:InterPro.
DR   CDD; cd16504; RING-HC_COP1; 1.
DR   CDD; cd00200; WD40; 1.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR   Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR   InterPro; IPR042755; COP1.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR019775; WD40_repeat_CS.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   InterPro; IPR001680; WD40_rpt.
DR   InterPro; IPR001841; Znf_RING.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   InterPro; IPR017907; Znf_RING_CS.
DR   PANTHER; PTHR44080; E3 UBIQUITIN-PROTEIN LIGASE COP1; 1.
DR   PANTHER; PTHR44080:SF1; E3 UBIQUITIN-PROTEIN LIGASE COP1; 1.
DR   Pfam; PF00400; WD40; 5.
DR   Pfam; PF13923; zf-C3HC4_2; 1.
DR   SMART; SM00184; RING; 1.
DR   SMART; SM00320; WD40; 6.
DR   SUPFAM; SSF57850; RING/U-box; 1.
DR   SUPFAM; SSF50978; WD40 repeat-like; 1.
DR   PROSITE; PS00678; WD_REPEATS_1; 1.
DR   PROSITE; PS50082; WD_REPEATS_2; 2.
DR   PROSITE; PS00518; ZF_RING_1; 1.
DR   PROSITE; PS50089; ZF_RING_2; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233060};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW   ProRule:PRU00221}; Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00175}.
FT   DOMAIN          136..174
FT                   /note="RING-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50089"
FT   REPEAT          485..527
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REPEAT          571..611
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REGION          1..44
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          278..324
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          231..258
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        1..40
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        280..324
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   707 AA;  77558 MW;  7333142995301222 CRC64;
     MSGSRQAGSG SAGTSPGSSA ASSVTSASSS LSSSPSPPSV AASAAALVSG GAAQPAGSGG
     LGGPVRPVLV APAVSGSGGG AVSTGLSRHS CVARPSAGVG GSSSSLGSGS RKRPLLAPLC
     NGLINSYEDK SNDFVCPICF DMIEEAYMTK CGHSFCYKCI HQSLEDNNRC PKCNYVVDNI
     DHLYPNFLVN ELILKQKQRF EEKRFKLDHS NGHRWQIFQD LLGTDQDNLD LANVNLMLEL
     LVQKKKQLEA ESHAAQLQIL MEFLKVARRN KREEMSGLYS PVSEDSTVPQ FEAPSPSHSS
     IIDSTEYSQP PGFSGSSQTK KQPWYNSTLA SRRKRLTAHF EDLEQCYFST RMSRISDDSR
     TASQLDEFQE CLSKFTRYNS VRPLATLSYA SDLYNGSSIV SSIEFDRDCD YFAIAGVTKK
     IKVYEYGTVI QDAVDIHYPE NEMTCNSKIS CISWSSYHKN LLASSDYEGT VILWDGFTGQ
     RSKVYQEHEK RCWSVDFNLM DPKLLASGSD DAKVKLWSTN LDNSVASIEA KANVCCVKFS
     PSSRYHLAFG CADHCVHYYD LRNTKQPIMV FKGHRKAVSY AKFVSGEEIV SASTDSQLKL
     WNVGKPYCLR SFKGHINEKN FVGLASNGDY IACGSENNSL YLYYKGLSKT LLTFKFDTVK
     SVLDKDRKED DTNEFVSAVC WRALPDGESN VLIAANSQGT IKVLELV
//