ID A0A2K5L1U7_CERAT Unreviewed; 312 AA.
AC A0A2K5L1U7;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Purine rich element binding protein B {ECO:0000313|Ensembl:ENSCATP00000006910.1};
GN Name=PURB {ECO:0000313|Ensembl:ENSCATP00000006910.1};
OS Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Cercocebus.
OX NCBI_TaxID=9531 {ECO:0000313|Ensembl:ENSCATP00000006910.1, ECO:0000313|Proteomes:UP000233060};
RN [1] {ECO:0000313|Ensembl:ENSCATP00000006910.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the PUR DNA-binding protein family.
CC {ECO:0000256|ARBA:ARBA00009251}.
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DR RefSeq; XP_011939859.1; XM_012084469.1.
DR AlphaFoldDB; A0A2K5L1U7; -.
DR SMR; A0A2K5L1U7; -.
DR STRING; 9531.ENSCATP00000006910; -.
DR Ensembl; ENSCATT00000024392.1; ENSCATP00000006910.1; ENSCATG00000021124.1.
DR GeneID; 105596897; -.
DR KEGG; caty:105596897; -.
DR CTD; 5814; -.
DR GeneTree; ENSGT00950000183162; -.
DR OMA; FQPAPRG; -.
DR OrthoDB; 1040548at2759; -.
DR Proteomes; UP000233060; Unplaced.
DR Bgee; ENSCATG00000021124; Expressed in cerebellum and 12 other cell types or tissues.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0140297; F:DNA-binding transcription factor binding; IEA:Ensembl.
DR GO; GO:0001227; F:DNA-binding transcription repressor activity, RNA polymerase II-specific; IEA:Ensembl.
DR GO; GO:0003729; F:mRNA binding; IEA:Ensembl.
DR GO; GO:0032422; F:purine-rich negative regulatory element binding; IEA:InterPro.
DR GO; GO:0000977; F:RNA polymerase II transcription regulatory region sequence-specific DNA binding; IEA:Ensembl.
DR GO; GO:0003697; F:single-stranded DNA binding; IEA:Ensembl.
DR GO; GO:0046332; F:SMAD binding; IEA:Ensembl.
DR GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IEA:Ensembl.
DR Gene3D; 3.10.450.700; -; 1.
DR Gene3D; 3.30.2450.30; -; 1.
DR InterPro; IPR006628; PUR-bd_fam.
DR PANTHER; PTHR12611; PUR-TRANSCRIPTIONAL ACTIVATOR; 1.
DR PANTHER; PTHR12611:SF4; TRANSCRIPTIONAL ACTIVATOR PROTEIN PUR-BETA; 1.
DR Pfam; PF04845; PurA; 1.
DR SMART; SM00712; PUR; 3.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000233060}.
FT REGION 1..36
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 197..220
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 284..312
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 284..301
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 312 AA; 33195 MW; 128AD4EE8CEC9FD9 CRC64;
MADGDSGSER GGGGGPGGFQ PASRGGGEQE TQELASKRLD IQNKRFYLDV KQNAKGRFLK
IAEVGAGGSK SRLTLSMAVA AEFRDSLGDF IEHYAQLGPS SPEQLAAGAE EGGGPRRALK
SEFLVRENRK YYLDLKENQR GRFLRIRQTV NRGGGGFGAG PGPGGLQSGQ TIALPAQGLI
EFRDALAKLI DDYGGEDDEL AGGPGGGAGG PGGGLYGELP EGTSITVDSK RFFFDVGCNK
YGVFLRVSEV KPSYRNAITV PFKAWGKFGG AFCRYADEMK EIQERQRDKL YERRGGGSGG
GEESEGEEVD ED
//
