ID A0A2K5L533_CERAT Unreviewed; 760 AA.
AC A0A2K5L533;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE SubName: Full=Seizure related 6 homolog like 2 {ECO:0000313|Ensembl:ENSCATP00000008058.1};
GN Name=SEZ6L2 {ECO:0000313|Ensembl:ENSCATP00000008058.1};
OS Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Cercocebus.
OX NCBI_TaxID=9531 {ECO:0000313|Ensembl:ENSCATP00000008058.1, ECO:0000313|Proteomes:UP000233060};
RN [1] {ECO:0000313|Ensembl:ENSCATP00000008058.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00302}.
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DR AlphaFoldDB; A0A2K5L533; -.
DR Ensembl; ENSCATT00000027732.1; ENSCATP00000008058.1; ENSCATG00000023404.1.
DR GeneTree; ENSGT00940000160492; -.
DR OMA; DPGFQIR; -.
DR Proteomes; UP000233060; Unplaced.
DR Bgee; ENSCATG00000023404; Expressed in cerebellum and 2 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00033; CCP; 4.
DR CDD; cd00041; CUB; 2.
DR Gene3D; 2.10.70.10; Complement Module, domain 1; 4.
DR Gene3D; 2.60.120.290; Spermadhesin, CUB domain; 2.
DR InterPro; IPR000859; CUB_dom.
DR InterPro; IPR035914; Sperma_CUB_dom_sf.
DR InterPro; IPR035976; Sushi/SCR/CCP_sf.
DR InterPro; IPR000436; Sushi_SCR_CCP_dom.
DR PANTHER; PTHR45656; PROTEIN CBR-CLEC-78; 1.
DR PANTHER; PTHR45656:SF2; SEIZURE 6-LIKE PROTEIN 2; 1.
DR Pfam; PF00431; CUB; 1.
DR Pfam; PF00084; Sushi; 4.
DR SMART; SM00032; CCP; 4.
DR SMART; SM00042; CUB; 2.
DR SUPFAM; SSF57535; Complement control module/SCR domain; 4.
DR SUPFAM; SSF49854; Spermadhesin, CUB domain; 2.
DR PROSITE; PS01180; CUB; 2.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
DR PROSITE; PS50923; SUSHI; 4.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00302}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000233060};
KW Signal {ECO:0000256|SAM:SignalP};
KW Sushi {ECO:0000256|ARBA:ARBA00022659, ECO:0000256|PROSITE-
KW ProRule:PRU00302}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..27
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 28..760
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014351004"
FT TRANSMEM 695..717
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 129..242
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 299..362
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 364..475
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 479..538
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 540..603
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 606..667
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT REGION 28..108
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 35..49
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 76..100
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 509..536
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
SQ SEQUENCE 760 AA; 81802 MW; 9DD18966B42BE238 CRC64;
MGTPRAQHPP PPQLLFLILL SCPWIQGSDP DPTLATPPAG QTLTVPSLPR ATEPGTGPLT
TAVTPKGVRG AGPTAPELLT PPPGTTAPPP PSPASPGPPL GPEGGEEETT TTIITTTTVT
TTVTSPVLCN NNISEGEGYV ESPDLESPAS RTLGLLDCTY SIHVYPGYGI EIQVQTLNLS
QEEELLVLAG GGSPGLAPRL LANSSMLGEG QVLRSPTNRL LLHFQSPRVP RGGGFRIHYQ
LMVRSGGSPL SPVIYDSDMD DVPERGLISD AQSLYVELLS ETPANPLLLS LRFEAFEEDR
CFAPFLAHGN VTTTDPEYRP GALATFSCLP GYALEPPGPP NAIECVDPTE PHWNDTEPAC
KAMCGGELSE PAGVVLSPDW PQSYSPGQDC VWGLHVQEEK RILLQVEILN VREGDMLTLF
DGDGPSARVL AQLRGPQPRR RLLSSGPDLT LQFQAPPGPP NPGLGQGFVL HFKEVPRNDT
CPELPPPEWG WRTASHGDLI RGTVLTYQCE PGYELLGSDI LTCQWDLSWS AAPPACQKIM
TCADPGEIAN GHRTASDAGF PVGSHVQYRC LPGYSLEGAA MLTCYSRDTG TPKWSDRVPK
CALKYEPCLN PGVPENGYQT LYKHHYQAGE SLRFFCYEGF ELIGEVTITC VPGHPSQWTS
QPPLCKVAYE ELLDNRKLEV TQTTDPSRQL EGGNLALAIL LPLGLVIVLG SGVYIYYTKL
QGKSLFGFSG SHSYSPITVE SDFSNPLYEA GDTREYEVSI
//
