ID A0A2K5L5H2_CERAT Unreviewed; 648 AA.
AC A0A2K5L5H2;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=G-protein coupled receptors family 2 profile 2 domain-containing protein {ECO:0000259|PROSITE:PS50261};
OS Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Cercocebus.
OX NCBI_TaxID=9531 {ECO:0000313|Ensembl:ENSCATP00000008197.1, ECO:0000313|Proteomes:UP000233060};
RN [1] {ECO:0000313|Ensembl:ENSCATP00000008197.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 2 family.
CC Adhesion G-protein coupled receptor (ADGR) subfamily.
CC {ECO:0000256|ARBA:ARBA00007343}.
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DR AlphaFoldDB; A0A2K5L5H2; -.
DR Ensembl; ENSCATT00000028364.1; ENSCATP00000008197.1; ENSCATG00000024511.1.
DR GeneTree; ENSGT00940000162401; -.
DR Proteomes; UP000233060; Unplaced.
DR Bgee; ENSCATG00000024511; Expressed in colon.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR GO; GO:0007166; P:cell surface receptor signaling pathway; IEA:InterPro.
DR CDD; cd15994; 7tmB2_GPR111_115; 1.
DR Gene3D; 2.60.220.50; -; 1.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR046338; GAIN_dom_sf.
DR InterPro; IPR017981; GPCR_2-like_7TM.
DR InterPro; IPR000832; GPCR_2_secretin-like.
DR InterPro; IPR000203; GPS.
DR PANTHER; PTHR45813:SF6; ADHESION G-PROTEIN COUPLED RECEPTOR F2; 1.
DR PANTHER; PTHR45813; EF-HAND DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00002; 7tm_2; 1.
DR Pfam; PF01825; GPS; 1.
DR PROSITE; PS50261; G_PROTEIN_RECEP_F2_4; 1.
DR PROSITE; PS50221; GPS; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000233060};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 388..411
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 423..448
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 468..491
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 498..523
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 543..567
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 588..611
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 386..629
FT /note="G-protein coupled receptors family 2 profile 2"
FT /evidence="ECO:0000259|PROSITE:PS50261"
SQ SEQUENCE 648 AA; 71818 MW; D0AE25A47B0681FD CRC64;
GSHVRSDVQA NSRGWGISQQ LPLSPNAACA LTAASKSKEK VPARPYGVCD GVCTDNSQCT
QPCPPDTQGN MGFSCRKKTW HKITDTCRTL NAVNIFEEDS QLVQPFEDNI KISVYTGKSE
TISDMLLQKC PTDLSCVIRG IQQSPRIPGN IAIIVQLLHN ISTALWTGVD EEKMRSYSTI
ANHILNSKSI SNWTFIPDRN SSYILLHSVN SFARRLFIDK YPVDIPDVFI HTMGTTISGD
NIGKNFTFSM RVNDTSNEVT GRVLISRDEL WKVPSPSQVI SIAFPTIGAI LEASLLENVT
INGLVLSVIL PKELKRISLI FEKISKSEER RTQCVGWHSV ENRWDQQACK MIQENSQQAV
CKCRPSKLFT SFSILMSPHI LESLILTYIT YIGLGISICS LILCLSIEVL VWSQVTKTEI
TYLRHVCIVN IAATLLMADV WFIVASFLSG PITHHSGCVA ATFFVHLFYL SVFFWMFAKA
LLILYGIMIV FHTLPKSVLV ASLFSVGYGC PLVIAAITVA ATQPGKGYLR PEACWLNWDM
TRALLAFVVP ALAIVVVNLI TVTLVIVKTQ RPAISNSMFQ EVRAIVRISK NIAILTPLLG
LTWGFGVATV INDRSLAFHI IFSLLNAFQV SPDASDQVQS ERIHEDVL
//
