ID A0A2K5L6V7_CERAT Unreviewed; 563 AA.
AC A0A2K5L6V7;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Zinc finger protein 461 {ECO:0000313|Ensembl:ENSCATP00000008679.1};
GN Name=ZNF461 {ECO:0000313|Ensembl:ENSCATP00000008679.1};
OS Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Cercocebus.
OX NCBI_TaxID=9531 {ECO:0000313|Ensembl:ENSCATP00000008679.1, ECO:0000313|Proteomes:UP000233060};
RN [1] {ECO:0000313|Ensembl:ENSCATP00000008679.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the krueppel C2H2-type zinc-finger protein
CC family. {ECO:0000256|ARBA:ARBA00006991}.
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DR RefSeq; XP_011935985.1; XM_012080595.1.
DR AlphaFoldDB; A0A2K5L6V7; -.
DR STRING; 9531.ENSCATP00000008679; -.
DR Ensembl; ENSCATT00000030337.1; ENSCATP00000008679.1; ENSCATG00000026207.1.
DR GeneID; 105595160; -.
DR CTD; 92283; -.
DR GeneTree; ENSGT00940000163325; -.
DR OrthoDB; 3120634at2759; -.
DR Proteomes; UP000233060; Unplaced.
DR Bgee; ENSCATG00000026207; Expressed in cerebellum and 12 other cell types or tissues.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd07765; KRAB_A-box; 1.
DR Gene3D; 6.10.140.140; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 11.
DR InterPro; IPR001909; KRAB.
DR InterPro; IPR036051; KRAB_dom_sf.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR24377; IP01015P-RELATED; 1.
DR PANTHER; PTHR24377:SF980; ZINC FINGER PROTEIN 420; 1.
DR Pfam; PF01352; KRAB; 1.
DR Pfam; PF00096; zf-C2H2; 10.
DR SMART; SM00349; KRAB; 1.
DR SMART; SM00355; ZnF_C2H2; 11.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 6.
DR SUPFAM; SSF109640; KRAB domain (Kruppel-associated box); 1.
DR PROSITE; PS50805; KRAB; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 11.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 12.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000233060};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00042}.
FT DOMAIN 6..77
FT /note="KRAB"
FT /evidence="ECO:0000259|PROSITE:PS50805"
FT DOMAIN 192..219
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 246..273
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 274..301
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 302..329
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 330..357
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 358..385
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 386..413
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 414..441
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 442..469
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 470..497
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 498..525
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 527..550
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
SQ SEQUENCE 563 AA; 66463 MW; B660BE0138976EA3 CRC64;
MAHELVMFRD VAIDVSQEEW ECLNPAQRNL YKEVMLENYS NLVSLGLSVS KPAIISSLEQ
GKEPWMVVRE ETGRWCPGTW KTWEFHNNFL DNNEATDIKA DLASRDEPQK LPPKSDIYET
ELFQWVNMEE FKSHSPERSI FRDIWEGNCH FEQHQGQEEG YFRQLMINHE NMHIFSQHTL
LTQEFYDREK ISECKKCRKI FSYHLYFSHH KRTHSKELSE CKECTEMVNT PCLFKQQTIQ
NGDKCNECKE CWKAFVHCSQ LKQHLRIHNG EKRYECNECG KAFNYGSELT LHQRIHTGEK
PYECKECGKA FRQRSQLTQH QRLHTGEKPY ECKQCGKAFI RGFQLTEHLR LHTGEKPYEC
KECGKTFRHR SHLTIHQRIH TGEKPYECRE CGKAFSYHSS FSHHQKIHSG KKPYECHECG
KAFCDGLQLT LHQRIHTGEK PYECKECGKT FRQCSHLKRH QRIHTGEKPH ECMICGKAFR
LHSHLIQHQR IHTGEKPYEC KECGKAFSYH SSFSHHQRIH SGKKPYQCGK AFNHGLQLNL
RQTLHTGEKP VRFPLLPPHP SLA
//
