ID   A0A2K5L8J8_CERAT        Unreviewed;      1581 AA.
AC   A0A2K5L8J8;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   24-JAN-2024, entry version 33.
DE   SubName: Full=Disco interacting protein 2 homolog A {ECO:0000313|Ensembl:ENSCATP00000009262.1};
GN   Name=DIP2A {ECO:0000313|Ensembl:ENSCATP00000009262.1};
OS   Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Cercocebus.
OX   NCBI_TaxID=9531 {ECO:0000313|Ensembl:ENSCATP00000009262.1, ECO:0000313|Proteomes:UP000233060};
RN   [1] {ECO:0000313|Ensembl:ENSCATP00000009262.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the DIP2 family.
CC       {ECO:0000256|ARBA:ARBA00007735}.
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DR   RefSeq; XP_011892951.1; XM_012037561.1.
DR   STRING; 9531.ENSCATP00000009262; -.
DR   Ensembl; ENSCATT00000032636.1; ENSCATP00000009262.1; ENSCATG00000025334.1.
DR   GeneID; 105575566; -.
DR   CTD; 23181; -.
DR   GeneTree; ENSGT00950000182997; -.
DR   OMA; CERPQVA; -.
DR   OrthoDB; 3994129at2759; -.
DR   Proteomes; UP000233060; Unplaced.
DR   Bgee; ENSCATG00000025334; Expressed in heart and 12 other cell types or tissues.
DR   GO; GO:0009986; C:cell surface; IEA:Ensembl.
DR   GO; GO:0016020; C:membrane; IEA:Ensembl.
DR   GO; GO:0010629; P:negative regulation of gene expression; IEA:Ensembl.
DR   CDD; cd05905; Dip2; 2.
DR   Gene3D; 3.30.300.30; -; 2.
DR   Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 2.
DR   InterPro; IPR045851; AMP-bd_C_sf.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR   InterPro; IPR042099; ANL_N_sf.
DR   InterPro; IPR037337; Dip2-like_dom.
DR   InterPro; IPR010506; DMAP1-bd.
DR   PANTHER; PTHR22754; DISCO-INTERACTING PROTEIN 2 DIP2 -RELATED; 1.
DR   PANTHER; PTHR22754:SF34; DISCO-INTERACTING PROTEIN 2 HOMOLOG A; 1.
DR   Pfam; PF00501; AMP-binding; 2.
DR   Pfam; PF06464; DMAP_binding; 1.
DR   SMART; SM01137; DMAP_binding; 1.
DR   SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 2.
DR   PROSITE; PS51912; DMAP1_BIND; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000233060}.
FT   DOMAIN          9..127
FT                   /note="DMAP1-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51912"
FT   REGION          60..210
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          302..327
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        64..82
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        83..97
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        123..140
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        168..190
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1581 AA;  171555 MW;  ED352E63C370863C CRC64;
     MADRGCPLEA APLPAEVRES LAELELELSE GDITQKGYEK KRAKLLARYI PLIQGIDPSL
     QAENRIPGPS QTTAAAPKQQ KSRPTTSRDE RFRSDVHTEA VQAALAKYKE RKMPMPSKRR
     SVLVHSSVET YTPPDTSSAS EDEGSLRRPG RLTSTPLQSH SSVEPWLDRV IQGSSTSSSA
     SSTSSHPGGR PTAAPSAAAT PGAAAATALA GREAHTHIDL HSAPPDVTTG LVEHSYFERP
     QVASVRSVPR GCSGSMLETA DGVPVNSRVS SKIQQLLNTL KRPKRPPLKE FFVDDFEELL
     EVQQPDPNQP KPEGSETSVL RGEPLTAGVP RPPSLLATLQ RWGTAQPKSP CLTALDTTGK
     ATYTLTYGKL WSRSLKLAYT LLNKLTSKNE PLLKPGDRVA LVFPNSDPVM FMVAFYGCLL
     AELVPVPIEV PLTRKDAGSQ QVGFLLGSCG VSLALTTDAC QKGLPKAQTG EVATFKGWPP
     LSWLVIDGKH LARPPKDWHP LTQDTRTGTA YIEYKTSKEG STVGVTVSHA SLLAQCRALT
     QACGYSEAET LTNVLDFKRD AGLWHGVLTS VMNRMHVVSI PYALMKANPL SWIQKVCFYK
     ARAALVKSRD MHWSLLAQRG QRDVSLSSLR MLIVADGANP WSISSCDAFL NVFQSRGLRP
     EVICPCASSP EALTVAIRRP PDLGGPPPRK AVLSMNGLSY GVIRVDTEEK LSVLTVQDVG
     QVMPGANVCV VKLEGSPYLC KTDEVGEICV NSSATGTAYY GLLGITKNVF EAVPVTAGGA
     PVFDRPFTRT GLLGFIGPDN LVFIVGKLDG LMVTGVRRHN ADDVVATALA VEPMKFVYRG
     RIAVFSVTVL HDDRVVLVAE QRPDASEEDS FQWMSRVLQA IDSIHQVGVY CLALVPANTL
     PKAPLGGIHI SETKQRFLEG TLHPCNVLMC PHTCVTNLPK PRQKPPEVGP ASMIVGNLVA
     GKRIAQASGR ELAHLEDSDQ ARKFLFLADV LQWRAHTTPD HPLFLLLNAK GTVTSTATCV
     QLHKRAERVA AALMEKGRLS VGDHVALVYP PGVDLIAAFY GCLYCGCVPV TVRPPHPQNL
     GTTLPTVKMI VEVSKSACVL TTQAVTRLLR SKEAAAAVDI RTWPTILDTD DIPKRKVASI
     FRPPSPDVLA YLDFSVSTTG ILAGVKMSHA ATSALCRSIK LQCELYPSRQ IAICLDPYCG
     LGFALWCLCS VYSGHQSVLV PPLELESNVS LWLSAVSQYK ARVTFCSYSV MEMCTKGLGA
     QTGVLRMKGV NLSCVRTCMV VAEERPRIAL TQSFSKLFKD LGLPARAVST TFGCRVNVAI
     CLQPNRLGKL AEQGTAGPDP TTVYVDMRAL RHDRVRLVER GSPHSLPLME SGKILPGVKV
     IIAHTETKGP LGDSHLGEIW VSSPHNATGY YTVYGEEALH ADHFSARLSF GDTQTIWART
     GYLGFLRRTE LTDASGGRHD ALYVVGSLDE TLELRGMRYH PIDIETSVIR AHRSIAECAV
     FTWTNLLVVV VELDGLEQDA LDLVALVTNV VLEEHYLVVG VVVIVDPGVI PINSRGEKQR
     MHLRDGFLAD QLDPIYVAYN M
//