ID   A0A2K5L8R2_CERAT        Unreviewed;       671 AA.
AC   A0A2K5L8R2;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 32.
DE   SubName: Full=Histone deacetylase 10 {ECO:0000313|Ensembl:ENSCATP00000009341.1};
GN   Name=HDAC10 {ECO:0000313|Ensembl:ENSCATP00000009341.1};
OS   Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Cercocebus.
OX   NCBI_TaxID=9531 {ECO:0000313|Ensembl:ENSCATP00000009341.1, ECO:0000313|Proteomes:UP000233060};
RN   [1] {ECO:0000313|Ensembl:ENSCATP00000009341.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR   AlphaFoldDB; A0A2K5L8R2; -.
DR   Ensembl; ENSCATT00000032914.1; ENSCATP00000009341.1; ENSCATG00000027781.1.
DR   GeneTree; ENSGT00940000160061; -.
DR   Proteomes; UP000233060; Unplaced.
DR   Bgee; ENSCATG00000027781; Expressed in thymus and 11 other cell types or tissues.
DR   GO; GO:0019899; F:enzyme binding; IEA:UniProt.
DR   GO; GO:0033558; F:protein lysine deacetylase activity; IEA:UniProt.
DR   GO; GO:0010558; P:negative regulation of macromolecule biosynthetic process; IEA:UniProt.
DR   Gene3D; 3.40.800.20; Histone deacetylase domain; 1.
DR   InterPro; IPR000286; His_deacetylse.
DR   InterPro; IPR023801; His_deacetylse_dom.
DR   InterPro; IPR037138; His_deacetylse_dom_sf.
DR   InterPro; IPR023696; Ureohydrolase_dom_sf.
DR   PANTHER; PTHR10625; HISTONE DEACETYLASE HDAC1-RELATED; 1.
DR   PANTHER; PTHR10625:SF18; POLYAMINE DEACETYLASE HDAC10; 1.
DR   Pfam; PF00850; Hist_deacetyl; 1.
DR   PRINTS; PR01270; HDASUPER.
DR   SUPFAM; SSF52768; Arginase/deacetylase; 2.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000233060}.
FT   DOMAIN          25..321
FT                   /note="Histone deacetylase"
FT                   /evidence="ECO:0000259|Pfam:PF00850"
FT   REGION          362..392
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        371..386
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   671 AA;  71731 MW;  0D359AA9B32C23A6 CRC64;
     MGTALVYHED MTATRDLWTE LFCEIERPER LTAALDRLRQ RGLEQRCLRL SAREASKAEL
     GLVHSPEYVS LVRKTQVLGE EELQALSGQF DAIYFHPSTF HCARLAAGAG LQLVDAVLTG
     AVQNGLALVR PPGHHSQRAA ANGFCVFNNV AIAAAHAKQK HGLHRILIVD WDVHHGQGIQ
     YLFEDDPSVL YFSWHRYEHG RFWPFLRESD ADAVGRGQGL GFTVNLPWNQ VGMGNADYVA
     AFLHLLLPLA FEFDPELVLV SAGFDSAIGD PEGQMQATPE CFAHLTHLLQ VLAGGRVCAM
     LEGGYHLESL AESVCMTVQT LLGDPAPPLS GLMVPCQSAL ESIQSARAAQ APYWKSLQLQ
     DVTPVPTSPS THSPEGRPPP LLPGGPMCKA AAPAPAPSSL LDQPCLCPAP SVRTTVALTA
     PDITLVLPPD VIQQEGSALR EETEAWARPH ESLAREEALT ALGKLLYLLD GMLDGQVNSG
     IAATPASAAA ATLDVAIQRG LSHGAQRLLC VALGQLDRPP DLAHDGRTLW LNIGGKEAAA
     LSMFHVSTPL PVMTGGFLSC ILGLVLPLAY GFQPDLVLVA LGPGHGLQGP HAALLAAMLR
     GLAGGRVLAL LEEDSTPQLA GILARVLRGE APPSLGPSSV ASPEDVQALM YLRGQLEPQW
     KMLQCRPHLV A
//