ID A0A2K5L8W7_CERAT Unreviewed; 657 AA.
AC A0A2K5L8W7;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Kirre like nephrin family adhesion molecule 1 {ECO:0000313|Ensembl:ENSCATP00000009391.1};
GN Name=KIRREL1 {ECO:0000313|Ensembl:ENSCATP00000009391.1};
OS Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Cercocebus.
OX NCBI_TaxID=9531 {ECO:0000313|Ensembl:ENSCATP00000009391.1, ECO:0000313|Proteomes:UP000233060};
RN [1] {ECO:0000313|Ensembl:ENSCATP00000009391.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
CC -!- SIMILARITY: Belongs to the immunoglobulin superfamily.
CC {ECO:0000256|ARBA:ARBA00008637}.
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DR AlphaFoldDB; A0A2K5L8W7; -.
DR Ensembl; ENSCATT00000033054.1; ENSCATP00000009391.1; ENSCATG00000028399.1.
DR GeneTree; ENSGT00940000155795; -.
DR Proteomes; UP000233060; Unplaced.
DR Bgee; ENSCATG00000028399; Expressed in spleen and 11 other cell types or tissues.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR CDD; cd00096; Ig; 1.
DR CDD; cd05759; IgI_2_KIRREL3-like; 1.
DR CDD; cd05898; IgI_5_KIRREL3; 1.
DR CDD; cd12087; TM_EGFR-like; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 4.
DR InterPro; IPR013162; CD80_C2-set.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR PANTHER; PTHR11640:SF14; KIN OF IRRE-LIKE PROTEIN 1; 1.
DR PANTHER; PTHR11640; NEPHRIN; 1.
DR Pfam; PF08205; C2-set_2; 1.
DR Pfam; PF13927; Ig_3; 1.
DR SMART; SM00409; IG; 4.
DR SMART; SM00408; IGc2; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 4.
DR PROSITE; PS50835; IG_LIKE; 4.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000233060};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..16
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 17..657
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014404098"
FT TRANSMEM 395..421
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 20..116
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 123..199
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 208..273
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 292..388
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 554..579
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 657 AA; 72708 MW; 45C3D85F2BACDDE7 CRC64;
MLSLLVWILT LSDTFSQVPP DDTRIDGGPV ILLQAGTPHN LTCRAFNAKP AATIIWFRDG
TQQEGAVAST ELLKDGKRET TVSQLLINPT DLDIGRVFTC RSMNEAIPSG KETSIELDVH
HPPTVTLSVE PQTVQEGERV VFTCQATANP EILGYRWAKG GFLIEDAHES RYETNVDYSF
FTEPVSCEVH NKVGSTNVST LVNVHFAPRI VVDPKPTTTD IGSDVTLTCV WVGNPPLTLT
WTKKDSNMVL SNSNQLLLKS VTQADAGTYT CRAIVPRIGV AEREVPLYVN GPPIISSEAV
QYAVRGDGGK VECFIGSTPP PDRIAWAWKE NFLEVGTLER YTVERTNSGS GVLSTLTINN
VMEADFQTHY NCTAWNSFGP GTAIIQLEER EVLPVGIIAG ATIGASILLI FFFIALVFFL
YRRRKGSRKD VTLRKLDIKV ETVNREPLTM HSDREDDTAS VSTATRVMKA IYSSFKDDVD
LKQDLRCDTI DTREEYEMKD PTNGYYNVRA HEDRPSSRAV LYADYRAPGP ARFDGRPSSR
LSHSSGYAQL NTYSRAPASD YGPEPTPPGP AAPAGTDTTS QLSYENYEKF NSHPFPGAAG
YPTYRLGYPQ APPSGLERTP YEAYDPIGKY ATATRFSYTS QHSDYGQRFQ QRMQTHV
//
