ID A0A2K5LAJ0_CERAT Unreviewed; 682 AA.
AC A0A2K5LAJ0;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Zinc finger protein 135 {ECO:0000313|Ensembl:ENSCATP00000009966.1};
GN Name=ZNF135 {ECO:0000313|Ensembl:ENSCATP00000009966.1};
OS Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Cercocebus.
OX NCBI_TaxID=9531 {ECO:0000313|Ensembl:ENSCATP00000009966.1, ECO:0000313|Proteomes:UP000233060};
RN [1] {ECO:0000313|Ensembl:ENSCATP00000009966.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the krueppel C2H2-type zinc-finger protein
CC family. {ECO:0000256|ARBA:ARBA00006991}.
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DR RefSeq; XP_011931638.1; XM_012076248.1.
DR AlphaFoldDB; A0A2K5LAJ0; -.
DR Ensembl; ENSCATT00000034073.1; ENSCATP00000009966.1; ENSCATG00000029283.1.
DR GeneID; 105593263; -.
DR CTD; 7694; -.
DR GeneTree; ENSGT00940000153104; -.
DR OrthoDB; 3086205at2759; -.
DR Proteomes; UP000233060; Unplaced.
DR Bgee; ENSCATG00000029283; Expressed in cerebellum and 11 other cell types or tissues.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0007010; P:cytoskeleton organization; IEA:Ensembl.
DR GO; GO:0022604; P:regulation of cell morphogenesis; IEA:Ensembl.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd07765; KRAB_A-box; 1.
DR Gene3D; 6.10.140.140; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 16.
DR InterPro; IPR001909; KRAB.
DR InterPro; IPR036051; KRAB_dom_sf.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR24384; FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED; 1.
DR PANTHER; PTHR24384:SF218; SI:DKEY-15H8.11 PROTEIN-RELATED; 1.
DR Pfam; PF01352; KRAB; 1.
DR Pfam; PF00096; zf-C2H2; 16.
DR SMART; SM00349; KRAB; 1.
DR SMART; SM00355; ZnF_C2H2; 16.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 10.
DR SUPFAM; SSF109640; KRAB domain (Kruppel-associated box); 1.
DR PROSITE; PS50805; KRAB; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 16.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 16.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000233060};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00042}.
FT DOMAIN 26..97
FT /note="KRAB"
FT /evidence="ECO:0000259|PROSITE:PS50805"
FT DOMAIN 238..265
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 266..293
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 294..321
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 322..349
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 350..377
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 378..405
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 406..433
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 434..461
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 462..489
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 490..517
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 518..545
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 546..573
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 574..601
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 602..629
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 630..657
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 658..682
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 194..220
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 682 AA; 78048 MW; ABF45808F9AA72D8 CRC64;
MESGARRRSV GRRCRGLCLA VRREQVTFED VVVDFSQEEW GQLKPAQRTL YRDVMLDTFR
LLVSVGHWLP KPNVISLLEQ EAEPRAVDSG VPPGVYPEIK GHFQFLLLSD LETRPKVKLS
VLKQGISEEI SNSVILVERF LWDSPWYCRG EDTEGHWEWS CESLESLAVP AAFTPVKTPV
QEQWQRNGFG ENVSLNPDLP HQPMTPEKQG PHMWGTRGKR EKPDLNVLQK TCVKEKPYKC
QECRKAFSHS SALIEHHRTH TGERPYECHE CGKGFRNSSA LTKHQRIHTG EKPYKCTQCG
RTFNQIAPLI QHQRTHTGEK PYECSECGKS FSFRSSFSQH ERTHTGEKPY ECSECGKAFR
QSIHLTQHLR IHTGEKPYQC GECGKAFSHS SSLTKHQRIH TGEKPYECHE CGKAFTQITP
LIQHQRTHTG EKPYECSECG KAFSQSTLLT EHRRIHTGEK PYGCNECGKT FSHSSSLSQH
ERTHTGEKPY ECSQCGKAFR QSTHLTQHQR IHTGEKPYEC NDCGKAFSHS SSLTKHQRIH
TGEKPYECNQ CGRAFSQLAP LIQHQRIHTG EKPYECNQCG RAFSQSSLLI EHQRIHTKEK
PYGCNECGKS FSHSSSLSQH ERTHTGEKPY ECHDCGKSFR QSTHLTQHRR IHTGEKPYAC
RDCGKAFTHS SSLTKHQRTH TG
//
