ID   A0A2K5LB13_CERAT        Unreviewed;       569 AA.
AC   A0A2K5LB13;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   RecName: Full=Phosphate transporter {ECO:0000256|RuleBase:RU363058};
GN   Name=SLC20A2 {ECO:0000313|Ensembl:ENSCATP00000010125.1};
OS   Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Cercocebus.
OX   NCBI_TaxID=9531 {ECO:0000313|Ensembl:ENSCATP00000010125.1, ECO:0000313|Proteomes:UP000233060};
RN   [1] {ECO:0000313|Ensembl:ENSCATP00000010125.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- FUNCTION: Sodium-phosphate symporter. {ECO:0000256|RuleBase:RU363058}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=2 Na(+)(out) + phosphate(out) = 2 Na(+)(in) + phosphate(in);
CC         Xref=Rhea:RHEA:71259, ChEBI:CHEBI:29101, ChEBI:CHEBI:43474;
CC         Evidence={ECO:0000256|ARBA:ARBA00035083};
CC   -!- SUBCELLULAR LOCATION: Apical cell membrane
CC       {ECO:0000256|ARBA:ARBA00004424}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004424}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU363058}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141,
CC       ECO:0000256|RuleBase:RU363058}.
CC   -!- SIMILARITY: Belongs to the inorganic phosphate transporter (PiT) (TC
CC       2.A.20) family. {ECO:0000256|ARBA:ARBA00009916,
CC       ECO:0000256|RuleBase:RU363058}.
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DR   AlphaFoldDB; A0A2K5LB13; -.
DR   STRING; 9531.ENSCATP00000010125; -.
DR   Ensembl; ENSCATT00000034232.1; ENSCATP00000010125.1; ENSCATG00000029328.1.
DR   GeneTree; ENSGT00390000014879; -.
DR   OMA; AWKTGNA; -.
DR   Proteomes; UP000233060; Unplaced.
DR   Bgee; ENSCATG00000029328; Expressed in heart and 12 other cell types or tissues.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005315; F:inorganic phosphate transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0005436; F:sodium:phosphate symporter activity; IEA:Ensembl.
DR   GO; GO:0001618; F:virus receptor activity; IEA:Ensembl.
DR   GO; GO:0006817; P:phosphate ion transport; IEA:UniProtKB-KW.
DR   InterPro; IPR001204; Phos_transporter.
DR   PANTHER; PTHR11101; PHOSPHATE TRANSPORTER; 1.
DR   PANTHER; PTHR11101:SF80; SODIUM-DEPENDENT PHOSPHATE TRANSPORTER 2; 1.
DR   Pfam; PF01384; PHO4; 2.
PE   3: Inferred from homology;
KW   Host-virus interaction {ECO:0000256|ARBA:ARBA00022581};
KW   Ion transport {ECO:0000256|ARBA:ARBA00023201};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363058};
KW   Phosphate transport {ECO:0000256|ARBA:ARBA00022592,
KW   ECO:0000256|RuleBase:RU363058};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233060};
KW   Sodium {ECO:0000256|ARBA:ARBA00023201};
KW   Sodium transport {ECO:0000256|ARBA:ARBA00023201};
KW   Symport {ECO:0000256|ARBA:ARBA00022847};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU363058};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU363058};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU363058}.
FT   TRANSMEM        6..26
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363058"
FT   TRANSMEM        111..133
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363058"
FT   TRANSMEM        145..163
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363058"
FT   TRANSMEM        175..198
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363058"
FT   TRANSMEM        402..421
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363058"
FT   TRANSMEM        451..468
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363058"
FT   TRANSMEM        535..566
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363058"
FT   REGION          375..394
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   569 AA;  61954 MW;  CB115B48D93838EC CRC64;
     MAMDEYLWMV ILGFIIAFIL AFSVGANDVA NSFGTAVGSG VVTLRQACIL ASIFETTGSV
     LLGAKVGETI RKGIIDVNLY NETVETLMAG EVSAMVGDSA KSQGSLVASW FISPLLSGFM
     SGLLFVLIRI FILKKEDPVP NGLRALPVFY AATIAINVFS IMYTGAPVLG LVLPMWAIAL
     ISFGVALLFA FFVWLFVCPW MRRKITGMVS DTSPHKVQGS KLPRCQAMTD APITAHRAQE
     TSDQSNTSAA PAPGCIRTCL RRFVRPTRGS YKDLLHKIHI DRGPEEKPAQ ESNYRLLRRN
     NSYTCYTAAI CGLPVHHTFR AADSSAPEDS EKLVGDTVSY SKKRLRYDSY SSYCNAVAEA
     EIEAEEGGVE MKLASELADP DQPREDPAEE EKEEKDAPEV HLLFHFLQVL TACFGSFAHG
     GNDVSNAIGP LVALWLIYKQ GGVMQEAATP VWLLFYGGVG ICTGLWVWGR RVIQTMGKDL
     TPITPSSGFT IELASAFTVV IASNIGLPVS TTHCKVGSVV AVGWIRSRKA VDWRLFRNIF
     VAWFVTVPVA GLFSAAVMAL LMYGILPYV
//