ID   A0A2K5LEU3_CERAT        Unreviewed;       341 AA.
AC   A0A2K5LEU3;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   24-JAN-2024, entry version 26.
DE   SubName: Full=NIPA magnesium transporter 2 {ECO:0000313|Ensembl:ENSCATP00000011412.1};
GN   Name=NIPA2 {ECO:0000313|Ensembl:ENSCATP00000011412.1};
OS   Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Cercocebus.
OX   NCBI_TaxID=9531 {ECO:0000313|Ensembl:ENSCATP00000011412.1, ECO:0000313|Proteomes:UP000233060};
RN   [1] {ECO:0000313|Ensembl:ENSCATP00000011412.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the NIPA family.
CC       {ECO:0000256|ARBA:ARBA00007230}.
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DR   RefSeq; XP_011931048.1; XM_012075658.1.
DR   AlphaFoldDB; A0A2K5LEU3; -.
DR   Ensembl; ENSCATT00000035534.1; ENSCATP00000011412.1; ENSCATG00000029912.1.
DR   GeneID; 105592981; -.
DR   CTD; 81614; -.
DR   GeneTree; ENSGT00940000155651; -.
DR   OrthoDB; 53219at2759; -.
DR   Proteomes; UP000233060; Unplaced.
DR   Bgee; ENSCATG00000029912; Expressed in lung and 12 other cell types or tissues.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015095; F:magnesium ion transmembrane transporter activity; IEA:InterPro.
DR   InterPro; IPR008521; Mg_trans_NIPA.
DR   PANTHER; PTHR12570:SF1; MAGNESIUM TRANSPORTER NIPA2; 1.
DR   PANTHER; PTHR12570; UNCHARACTERIZED; 1.
DR   Pfam; PF05653; Mg_trans_NIPA; 1.
DR   SUPFAM; SSF103481; Multidrug resistance efflux transporter EmrE; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233060};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..30
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        132..152
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        159..184
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        196..216
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        228..249
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        261..280
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   341 AA;  36882 MW;  F4B2C2718B874713 CRC64;
     MSQGRGKYDF YIGLGLAMSS SIFIGGSFIL KKKGLLRLAR KGSMRAVGAG EVANFAAYAF
     APATLVTPLG ALSVLVSAIL SSYFLNERLN LHGKIGCLLS ILGSTVMVIH APKEEEIETL
     NEMSHKLGDP GFVVFATLVV IVALILIFAV GPRHGQTNIL VYITICSVIG AFSVSCVKGL
     GIALKELFAG KPVLRHPLAW VLLLSLIVCV STQINYLNRA LDIFNTSIVT PIYYVFFTTS
     VLTCSAILFK EWQDMPGDDV IGTLSGFFTI IVGIFLLHAF KDVSFSLASL PVSFRKDEKA
     VNGNLSNMYE VLNNNEESLT CGIEQHTGEN VSRRNGNLTA F
//