ID   A0A2K5LFB3_CERAT        Unreviewed;       638 AA.
AC   A0A2K5LFB3;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   RecName: Full=Cytoplasmic dynein 1 intermediate chain 2 {ECO:0000256|ARBA:ARBA00040292};
DE   AltName: Full=Cytoplasmic dynein intermediate chain 2 {ECO:0000256|ARBA:ARBA00042023};
DE   AltName: Full=Dynein intermediate chain 2, cytosolic {ECO:0000256|ARBA:ARBA00042966};
GN   Name=DYNC1I2 {ECO:0000313|Ensembl:ENSCATP00000011619.1};
OS   Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Cercocebus.
OX   NCBI_TaxID=9531 {ECO:0000313|Ensembl:ENSCATP00000011619.1, ECO:0000313|Proteomes:UP000233060};
RN   [1] {ECO:0000313|Ensembl:ENSCATP00000011619.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC   -!- SIMILARITY: Belongs to the dynein intermediate chain family.
CC       {ECO:0000256|ARBA:ARBA00011059}.
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DR   AlphaFoldDB; A0A2K5LFB3; -.
DR   SMR; A0A2K5LFB3; -.
DR   STRING; 9531.ENSCATP00000011619; -.
DR   Ensembl; ENSCATT00000035745.1; ENSCATP00000011619.1; ENSCATG00000029930.1.
DR   GeneTree; ENSGT00940000155442; -.
DR   Proteomes; UP000233060; Unplaced.
DR   Bgee; ENSCATG00000029930; Expressed in heart and 12 other cell types or tissues.
DR   GO; GO:0005813; C:centrosome; IEA:Ensembl.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005868; C:cytoplasmic dynein complex; IEA:InterPro.
DR   GO; GO:0005874; C:microtubule; IEA:Ensembl.
DR   GO; GO:0031982; C:vesicle; IEA:Ensembl.
DR   GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR   InterPro; IPR025956; DYNC1I1/DYNC1I2.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   InterPro; IPR001680; WD40_rpt.
DR   PANTHER; PTHR12442:SF37; CYTOPLASMIC DYNEIN 1 INTERMEDIATE CHAIN 2; 1.
DR   PANTHER; PTHR12442; DYNEIN INTERMEDIATE CHAIN; 1.
DR   Pfam; PF11540; Dynein_IC2; 1.
DR   Pfam; PF00400; WD40; 1.
DR   SMART; SM00320; WD40; 5.
DR   SUPFAM; SSF50978; WD40 repeat-like; 1.
PE   3: Inferred from homology;
KW   Dynein {ECO:0000256|ARBA:ARBA00023017};
KW   Motor protein {ECO:0000256|ARBA:ARBA00023175};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233060};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   WD repeat {ECO:0000256|ARBA:ARBA00022574}.
FT   REGION          1..135
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          155..214
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..62
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        85..108
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        180..214
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   638 AA;  71457 MW;  2F868EC9556C47F2 CRC64;
     MSDKSELKAE LERKKQRLAQ IREEKKRKEE ERKKKETDQK KEAVAPVQEE SDLEKKRREA
     EALLQSMGLT PESPIVFSEY WVPPPMSPSS KSVSTPSEAG SQDSGDGAVG SRTLHWDTDP
     SVLQLHSDSD LGRGPIKLGM AKITQVDFPP REIVTYTKET QTPVMAQPKE DEEEDDDVVA
     PKPPIEPEEE KTLKKDEEND SKAPPHELTE EEKQQILHSE EFLSFFDHST RIVERALSEQ
     INIFFDYSGR DLEDKEGEIQ AGAKLSLNRQ FFDERWSKHR VVSCLDWSSQ YPELLVASYN
     NNEDAPHEPD GVALVWNMKY KKTTPEYVFH CQSAVMSATF AKFHPNLVVG GTYSGQIVLW
     DNRSNKRTPV QRTPLSAAAH THPVYCVNVV GTQNAHNLIS ISTDGKICSW SLDMLSHPQD
     SMELVHKQSK AVAVTSMSFP VGDVNNFVVG SEEGSVYTAC RHGSKAGISE MFEGHQGPIT
     GIHCHAAVGA VDFSHLFVTS SFDWTVKLWT TKNNKPLYSF EDNADYVYDV MWSPTHPALF
     ACVDGMGRLD LWNLNNDTEV PTASISVEGN PALNRVRWTH SGREIAVGDS EGQIVIYDVG
     EQIAVPRNDE WARFGRTLAE INANRADAEE EAATRIPA
//