ID A0A2K5LJP3_CERAT Unreviewed; 313 AA.
AC A0A2K5LJP3;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE SubName: Full=NCK adaptor protein 1 {ECO:0000313|Ensembl:ENSCATP00000013133.1};
GN Name=NCK1 {ECO:0000313|Ensembl:ENSCATP00000013133.1};
OS Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Cercocebus.
OX NCBI_TaxID=9531 {ECO:0000313|Ensembl:ENSCATP00000013133.1, ECO:0000313|Proteomes:UP000233060};
RN [1] {ECO:0000313|Ensembl:ENSCATP00000013133.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A2K5LJP3; -.
DR Ensembl; ENSCATT00000037268.1; ENSCATP00000013133.1; ENSCATG00000030699.1.
DR GeneTree; ENSGT00940000156601; -.
DR Proteomes; UP000233060; Unplaced.
DR Bgee; ENSCATG00000030699; Expressed in lung and 12 other cell types or tissues.
DR GO; GO:0005829; C:cytosol; IEA:UniProt.
DR CDD; cd10408; SH2_Nck1; 1.
DR CDD; cd11901; SH3_Nck1_2; 1.
DR CDD; cd11904; SH3_Nck1_3; 1.
DR Gene3D; 3.30.505.10; SH2 domain; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 2.
DR InterPro; IPR017304; NCK.
DR InterPro; IPR035882; Nck1_SH2.
DR InterPro; IPR035564; Nck1_SH3_2.
DR InterPro; IPR035565; Nck1_SH3_3.
DR InterPro; IPR000980; SH2.
DR InterPro; IPR036860; SH2_dom_sf.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR19969:SF16; CYTOPLASMIC PROTEIN NCK1; 1.
DR PANTHER; PTHR19969; SH2-SH3 ADAPTOR PROTEIN-RELATED; 1.
DR Pfam; PF00017; SH2; 1.
DR Pfam; PF00018; SH3_1; 2.
DR PIRSF; PIRSF037874; Cytoplasmic_NCK; 1.
DR PRINTS; PR00401; SH2DOMAIN.
DR PRINTS; PR00452; SH3DOMAIN.
DR SMART; SM00252; SH2; 1.
DR SMART; SM00326; SH3; 2.
DR SUPFAM; SSF55550; SH2 domain; 1.
DR SUPFAM; SSF50044; SH3-domain; 2.
DR PROSITE; PS50001; SH2; 1.
DR PROSITE; PS50002; SH3; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000233060};
KW SH2 domain {ECO:0000256|PROSITE-ProRule:PRU00191};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 42..101
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 126..188
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 218..312
FT /note="SH2"
FT /evidence="ECO:0000259|PROSITE:PS50001"
SQ SEQUENCE 313 AA; 35355 MW; B9AAB9EB84745A76 CRC64;
QPPPPGFKQF FCIGKVKRKP SVPDSASPAD DSFVDPGERL YDLNMPAYVK FNYMAEREDE
LSLIKGTKVI VMEKCSDGWW RGSYNGQVGW FPSNYVTEEG DSPLGDHVGS LSEKLAAVVN
NLNTGQVLHV VQALYPFSSS NDEELNFEKG DVMDVIEKPE NDPEWWKCRK INGMVGLVPK
NYVTVMQNNP LTSGLEPSPP QCDYIRPSLT GKFAGNPWYY GKVTRHQAEM ALNERGHEGD
FLIRDSESSP NDFSVSLKAQ GKNKHFKVQL KETVYCIGQR KFSTMEELVE HYKKAPIFTS
EQGEKLYLVK HLS
//
