ID A0A2K5LN79_CERAT Unreviewed; 473 AA.
AC A0A2K5LN79;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE SubName: Full=ETS2 repressor factor {ECO:0000313|Ensembl:ENSCATP00000014397.1};
GN Name=ERF {ECO:0000313|Ensembl:ENSCATP00000014397.1};
OS Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Cercocebus.
OX NCBI_TaxID=9531 {ECO:0000313|Ensembl:ENSCATP00000014397.1, ECO:0000313|Proteomes:UP000233060};
RN [1] {ECO:0000313|Ensembl:ENSCATP00000014397.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU004019}.
CC -!- SIMILARITY: Belongs to the ETS family. {ECO:0000256|ARBA:ARBA00005562,
CC ECO:0000256|RuleBase:RU004019}.
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DR RefSeq; XP_011942319.1; XM_012086929.1.
DR RefSeq; XP_011942320.1; XM_012086930.1.
DR RefSeq; XP_011942321.1; XM_012086931.1.
DR RefSeq; XP_011942323.1; XM_012086933.1.
DR AlphaFoldDB; A0A2K5LN79; -.
DR Ensembl; ENSCATT00000038544.1; ENSCATP00000014397.1; ENSCATG00000031239.1.
DR GeneID; 105598054; -.
DR CTD; 2077; -.
DR GeneTree; ENSGT00940000157292; -.
DR OMA; GGHFRFP; -.
DR OrthoDB; 4182934at2759; -.
DR Proteomes; UP000233060; Unplaced.
DR Bgee; ENSCATG00000031239; Expressed in adult mammalian kidney and 10 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000418; Ets_dom.
DR InterPro; IPR046328; ETS_fam.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11849; ETS; 1.
DR PANTHER; PTHR11849:SF59; ETS DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00178; Ets; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50061; ETS_DOMAIN_3; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU004019};
KW Nucleus {ECO:0000256|RuleBase:RU004019};
KW Reference proteome {ECO:0000313|Proteomes:UP000233060}.
FT DOMAIN 1..32
FT /note="ETS"
FT /evidence="ECO:0000259|PROSITE:PS50061"
FT REGION 55..94
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 109..150
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 205..229
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 267..403
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 417..473
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 68..94
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 267..284
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 285..302
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 359..375
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 473 AA; 49963 MW; 8AA082BCF8D58FC9 CRC64;
MNYDKLSRAL RYYYNKRILH KTKGKRFTYK FNFNKLVLVN YPFIDVGLAG GAVPQSAPPV
PSGGSHFRFP PSTPSEVLSP TEDPRSPPAC SSSSSSLFSA VVARRLGRGS VSDCSDGTSE
LEEPLGEDPR ARPPGPPDLG AFRGPPLARL PHDPGVFRVY PRPRGGPEPL SPFPVSPLAG
PGSLLPPQLS PALPMTPTHL AYTPSPTLSP MYPSGGGGPS GSGGGSHFSF SPEDMKRYLQ
AHTQSVYNYH LSPRAFLHYP GLVVPQPQRP DKCPLPPMAP ETPPVPSSAS SSSSSSSSPF
KFKLQPPPLG RRQRAAGEKA PAGADQSGGS AGGLAEGAGA LAPPPPPPQI KVEPISEGES
EEVEVTDISD EDEEDGEVFK TPRAPPAPPK PEPGEAPGAS QCMPLKLRFK RRWSEDCRLE
GGGGPAGGFE DEGEDKKVRG EGPGEAGGPL TPRRVSSDLQ HATAQLSLEH RDS
//
