ID   A0A2K5LNS8_CERAT        Unreviewed;       800 AA.
AC   A0A2K5LNS8;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=GTPase activating Rap/RanGAP domain like 3 {ECO:0000313|Ensembl:ENSCATP00000014558.1};
GN   Name=GARNL3 {ECO:0000313|Ensembl:ENSCATP00000014558.1};
OS   Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Cercocebus.
OX   NCBI_TaxID=9531 {ECO:0000313|Ensembl:ENSCATP00000014558.1, ECO:0000313|Proteomes:UP000233060};
RN   [1] {ECO:0000313|Ensembl:ENSCATP00000014558.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A2K5LNS8; -.
DR   Ensembl; ENSCATT00000038705.1; ENSCATP00000014558.1; ENSCATG00000031241.1.
DR   GeneTree; ENSGT00940000159362; -.
DR   OMA; FEGYSER; -.
DR   Proteomes; UP000233060; Unplaced.
DR   Bgee; ENSCATG00000031241; Expressed in cerebellum and 11 other cell types or tissues.
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.
DR   Gene3D; 3.40.50.11210; Rap/Ran-GAP; 1.
DR   InterPro; IPR001180; CNH_dom.
DR   InterPro; IPR035974; Rap/Ran-GAP_sf.
DR   InterPro; IPR000331; Rap/Ran_GAP_dom.
DR   PANTHER; PTHR15711:SF62; GTPASE-ACTIVATING RAP_RAN-GAP DOMAIN-LIKE PROTEIN 3; 1.
DR   PANTHER; PTHR15711; RAP GTPASE-ACTIVATING PROTEIN; 1.
DR   Pfam; PF00780; CNH; 1.
DR   Pfam; PF21022; Rap-GAP_dimer; 1.
DR   Pfam; PF02145; Rap_GAP; 1.
DR   SUPFAM; SSF111347; Rap/Ran-GAP; 1.
DR   PROSITE; PS50219; CNH; 1.
DR   PROSITE; PS50085; RAPGAP; 1.
PE   4: Predicted;
KW   GTPase activation {ECO:0000256|ARBA:ARBA00022468, ECO:0000256|PROSITE-
KW   ProRule:PRU00165}; Reference proteome {ECO:0000313|Proteomes:UP000233060}.
FT   DOMAIN          173..389
FT                   /note="Rap-GAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50085"
FT   DOMAIN          471..780
FT                   /note="CNH"
FT                   /evidence="ECO:0000259|PROSITE:PS50219"
SQ   SEQUENCE   800 AA;  90535 MW;  E66B58A29B572ECC CRC64;
     MKHFCSSSVS EDLGCRRGDF SRKHYGSVEL LISSDADGAI QRAGRFRVEN GSSDENATAL
     PGTWRRTDVH LENPEYHTRW YFKYFLGQVH QNYIGNDAEK SPFFLSVTLS DQNNQRVPQY
     RAILWRKTGT QKICLPYSPT KTLSVKSILS AMNLDKFEKG PREIFHPEIQ KDLLVLEEQE
     GSVNFKFGVL FAKDGQLTDD EMFSNEIGSE PFQKFLNLLG DTITLKGWTG YRGGLDTKND
     TTGIHSVYTV YQGHEIMFHV STMLPYSKEN KQQVERKRHI GNDIVTIVFQ EGEESSPAFK
     PSMIRSHFTH IFALVRYDQQ NDSYRLKIFS EESVPLFGPP LPTPPVFTDH QEFRDFLLVK
     LINGEKATLE TPTFAQKRRR TLDMLIRSLH QDLMPDLHKN MLNRRSFSDV LPESPKSARK
     KEEARQAEFV RIGQALKLKS IVRGDAPSSL AASGICKKEP WEPQCFCSNF PHEAVCADPW
     GQALLVSTDA GVLLVDVLVF LHSRPLEALQ VTLLFHLISS SALFMSLGKD ARLFVFRLSA
     LQKGLEGKQT GKSRSDCREN KLEKTKGCHL YAINTHHSRE LRIVVAIRNK LLLITRKHNK
     PSGVSSTSLL SPLSESPVEE FQYIREICLS DSPVVMTLVD GPAEESDNLI CVAYRHQFDM
     VNESTGEAFR LHHVEANRVN FVAAIDVYED GEAGLLLCYN YSCIYKKVCP FNGGSFLVQP
     SASDFQFCWN QAPCAIVCAF PYLLAFTTDS MEIRLVVNGN LVHTAVVPQL QLVASRVKFN
     QKICTRFHLE TSWAEASSDL
//