ID A0A2K5LNW3_CERAT Unreviewed; 780 AA.
AC A0A2K5LNW3;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE RecName: Full=Protein phosphatase 1 regulatory subunit 21 {ECO:0000256|ARBA:ARBA00020102};
DE AltName: Full=Coiled-coil domain-containing protein 128 {ECO:0000256|ARBA:ARBA00031617};
DE AltName: Full=KLRAQ motif-containing protein 1 {ECO:0000256|ARBA:ARBA00031361};
GN Name=PPP1R21 {ECO:0000313|Ensembl:ENSCATP00000014650.1};
OS Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Cercocebus.
OX NCBI_TaxID=9531 {ECO:0000313|Ensembl:ENSCATP00000014650.1, ECO:0000313|Proteomes:UP000233060};
RN [1] {ECO:0000313|Ensembl:ENSCATP00000014650.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Early endosome {ECO:0000256|ARBA:ARBA00004412}.
CC Endosome {ECO:0000256|ARBA:ARBA00004177}.
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DR RefSeq; XP_011925735.1; XM_012070345.1.
DR AlphaFoldDB; A0A2K5LNW3; -.
DR STRING; 9531.ENSCATP00000014650; -.
DR Ensembl; ENSCATT00000038798.1; ENSCATP00000014650.1; ENSCATG00000031248.1.
DR GeneID; 105590618; -.
DR CTD; 129285; -.
DR GeneTree; ENSGT00390000006820; -.
DR OMA; NLHTYTE; -.
DR OrthoDB; 2882462at2759; -.
DR Proteomes; UP000233060; Unplaced.
DR Bgee; ENSCATG00000031248; Expressed in pituitary gland and 12 other cell types or tissues.
DR GO; GO:0005769; C:early endosome; IEA:UniProtKB-SubCell.
DR InterPro; IPR040024; PPP1R21.
DR InterPro; IPR049372; PPP1R21_C.
DR InterPro; IPR019343; PPP1R21_N.
DR InterPro; IPR019348; PPP1R21_six_helix.
DR PANTHER; PTHR21448:SF0; PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 21; 1.
DR PANTHER; PTHR21448; SMOOTH MUSCLE MYOSIN HEAVY CHAIN-RELATED; 1.
DR Pfam; PF10205; KLRAQ; 1.
DR Pfam; PF21636; PPP1R21_C; 1.
DR Pfam; PF10212; PPP1R21_helical; 1.
DR SMART; SM01254; KLRAQ; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Endosome {ECO:0000256|ARBA:ARBA00022753};
KW Reference proteome {ECO:0000313|Proteomes:UP000233060}.
FT DOMAIN 11..112
FT /note="Protein phosphatase 1 regulatory subunit 21 N-
FT terminal"
FT /evidence="ECO:0000259|SMART:SM01254"
FT REGION 84..104
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 760..780
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 3..72
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 137..196
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 558..592
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 696..737
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 780 AA; 88331 MW; 9FF179E1482DDD0E CRC64;
MASAELQGKY QKLAQEYSKL RAQNQVLKKG VVDEQANSAA LKEQLKMKDQ SLRKLQQEMD
SLTFRNLQLA KRVELLQDEL ALSEPRGKKN KKSGESSSQL SQEQKTVFDE DLQKKIEENE
RLHIQFFEAD EQHKHVEAEL RSRLATLETE AAQHQAVVDG LTRKYMETIE KLQNDKAKLE
VKSQTLEKEA KECRLRTEEC QLQLKNLHED LSGRLEESLS IINEKVPFND TKYSQYNALN
VPLHNRRHQL KMRDIAGQAL AFVQDLVTAL LNFHTYTEQR IQIFPVDSAI DTISPLNQKF
SQYLHENASY VRPLEEGMLH LFESITEDTV TVLETTVKLK TFSEHLTSYI CFLRKILPYQ
LKSLEEECES SLCTSALRAR NLELSQDMKK MTAVFEKLQT YIALLALPST EPDGLLRTNY
SSVLTNVGAA LHGFHDIMKD ISKHYSQKAT IEHELPTATQ KLITTNDCIL SSVVALTNGA
GKIASFFSNN LDYFIASLSY GPKAASGFIS PLSAECMLQY KKKAAAYMKS LRKPLLESVP
YEEALANRRV LLSSTESREG LAQQVQQSLE KISKLEQEKE HWMLEAQLAK IKLEKENQRI
ADKLKNTSSG QLVGLAQENA AVSNAAGQDE ATAKAVSEPI QSTSLIGTLT RTSDSEVPDV
ESREDLIKNH YMARIVELTS QLQLADSKSV HFYAECRALS KRLALAEKSK EALTEEMKLA
SQNISRLQDE LTTTKRSYED QLSMMSDHLC SMNETLSKQR EEIDTLKMSS KGNSKKNKSR
//
