ID A0A2K5LR17_CERAT Unreviewed; 396 AA.
AC A0A2K5LR17;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE RecName: Full=Keratin, type I cytoskeletal 19 {ECO:0000256|ARBA:ARBA00040324};
DE AltName: Full=Cytokeratin-19 {ECO:0000256|ARBA:ARBA00041710};
DE AltName: Full=Keratin-19 {ECO:0000256|ARBA:ARBA00042489};
GN Name=KRT19 {ECO:0000313|Ensembl:ENSCATP00000015395.1};
OS Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Cercocebus.
OX NCBI_TaxID=9531 {ECO:0000313|Ensembl:ENSCATP00000015395.1, ECO:0000313|Proteomes:UP000233060};
RN [1] {ECO:0000313|Ensembl:ENSCATP00000015395.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- FUNCTION: Involved in the organization of myofibers. Together with
CC KRT8, helps to link the contractile apparatus to dystrophin at the
CC costameres of striated muscle. {ECO:0000256|ARBA:ARBA00037562}.
CC -!- SIMILARITY: Belongs to the intermediate filament family.
CC {ECO:0000256|RuleBase:RU000685}.
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DR RefSeq; XP_011902009.1; XM_012046619.1.
DR AlphaFoldDB; A0A2K5LR17; -.
DR STRING; 9531.ENSCATP00000015395; -.
DR Ensembl; ENSCATT00000039549.1; ENSCATP00000015395.1; ENSCATG00000031681.1.
DR GeneID; 105579639; -.
DR KEGG; caty:105579639; -.
DR CTD; 3880; -.
DR GeneTree; ENSGT00940000155258; -.
DR OMA; YWATIND; -.
DR OrthoDB; 4640531at2759; -.
DR Proteomes; UP000233060; Unplaced.
DR Bgee; ENSCATG00000031681; Expressed in colon and 8 other cell types or tissues.
DR GO; GO:0005882; C:intermediate filament; IEA:UniProtKB-KW.
DR GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 1.20.5.500; Single helix bin; 1.
DR Gene3D; 1.20.5.1160; Vasodilator-stimulated phosphoprotein; 1.
DR InterPro; IPR018039; IF_conserved.
DR InterPro; IPR039008; IF_rod_dom.
DR InterPro; IPR002957; Keratin_I.
DR PANTHER; PTHR23239; INTERMEDIATE FILAMENT; 1.
DR PANTHER; PTHR23239:SF14; KERATIN, TYPE I CYTOSKELETAL 19; 1.
DR Pfam; PF00038; Filament; 1.
DR PRINTS; PR01248; TYPE1KERATIN.
DR SMART; SM01391; Filament; 1.
DR SUPFAM; SSF64593; Intermediate filament protein, coiled coil region; 2.
DR SUPFAM; SSF46579; Prefoldin; 1.
DR PROSITE; PS00226; IF_ROD_1; 1.
DR PROSITE; PS51842; IF_ROD_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Intermediate filament {ECO:0000256|ARBA:ARBA00022754,
KW ECO:0000256|RuleBase:RU000685};
KW Reference proteome {ECO:0000313|Proteomes:UP000233060}.
FT DOMAIN 76..387
FT /note="IF rod"
FT /evidence="ECO:0000259|PROSITE:PS51842"
FT COILED 80..107
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 179..213
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 285..326
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 352..386
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 396 AA; 43747 MW; 78BB6F886EB7BD8D CRC64;
MTSYSYRQSS ATSSFGGLGG GSVRFGPGVA FRAPSMHGGS GGRGVSVSSA RFVSSSSSGG
YGGVLAASDG LLAGNEKLTM QNLNDRLASY LDKVRALQAA NGELEVKIRD WYQKQGPGPS
RDYSHYYTTI QDLRDKILGA TIENSRIVLQ IDNARLAADD FRTKFETEQA LRMSVEADIN
GLRRVLDELT LARTDLEMQI EGLKEELAYL KKNHEEEISV LRGQVGGQVS VEVDSAPGTD
LAKILNDMRS QYQVMAEQNR KDAEAWFTSR TEELNREVAG HTEQLQISRS EVTDLRRTLQ
GLEIELQSQL SMKAALEDTL AETEARFGAQ LAHIQALISG VEAQLGDVRA DSERQNQEYQ
RLMDIKSRLE QEIATYRSLL EGQEDHYNNL PASKVL
//
