ID A0A2K5LXQ3_CERAT Unreviewed; 544 AA.
AC A0A2K5LXQ3;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Death inducer-obliterator 1 {ECO:0000313|Ensembl:ENSCATP00000017726.1};
GN Name=DIDO1 {ECO:0000313|Ensembl:ENSCATP00000017726.1};
OS Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Cercocebus.
OX NCBI_TaxID=9531 {ECO:0000313|Ensembl:ENSCATP00000017726.1, ECO:0000313|Proteomes:UP000233060};
RN [1] {ECO:0000313|Ensembl:ENSCATP00000017726.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR AlphaFoldDB; A0A2K5LXQ3; -.
DR Ensembl; ENSCATT00000041894.1; ENSCATP00000017726.1; ENSCATG00000032733.1.
DR GeneTree; ENSGT00940000155532; -.
DR Proteomes; UP000233060; Unplaced.
DR Bgee; ENSCATG00000032733; Expressed in thymus and 12 other cell types or tissues.
DR GO; GO:0048188; C:Set1C/COMPASS complex; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0097190; P:apoptotic signaling pathway; IEA:InterPro.
DR CDD; cd15639; PHD_DIDO1_like; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR033082; DIDO1_PHD.
DR InterPro; IPR037869; Spp1/CFP1.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR46174; CXXC-TYPE ZINC FINGER PROTEIN 1; 1.
DR PANTHER; PTHR46174:SF1; CXXC-TYPE ZINC FINGER PROTEIN 1; 1.
DR Pfam; PF00628; PHD; 1.
DR SMART; SM00249; PHD; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR PROSITE; PS01359; ZF_PHD_1; 1.
DR PROSITE; PS50016; ZF_PHD_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000233060};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00146}.
FT DOMAIN 268..322
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT REGION 1..260
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 327..350
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 431..451
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..44
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 65..91
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 94..135
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 136..200
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 227..260
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 433..449
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 544 AA; 59336 MW; EA378E88C0FEEB8F CRC64;
MDDKGDPSNE EAPKAIKPTS KEFRKTWGFR RTTIAKREGA GDAEADPLEP PPPQQQLGLS
LRRSGRQPKR TERVEQFLTI ARRRGRRSAP VSLEDSGEPT SCPATDAETA SEGSVESASE
TRSGTQSAST PVKERPTSSE KVKGGDDHDD TSDSDSDGLT LKELQNRLRR KREQEPTERP
LKGIQSRLRK KRREEGPAET VGSEASDTVE GVLPSKQEPE NDQGTASQAG KDDRESKLEG
KAAQDVKEEE PGDSGRPKPE CEGYDPNALY CICRQPHNNR FMICCDRCEE WFHGDCVGIS
EARGRLLERN GEDYICPNCT ILQVQDETNS ETADQQEAKL RPGDADGTDC TSIGTIEQKS
SEDQGIKGRI EKAANPSGKK KLKIFQPVIE TPGASKCIGP GCCQVAQPDS VYCSNDCILK
HAAATMKFLS SGKEQKPKPK EKMKMKPEKP SLPKCGVQAG IKISSVHKRP APEKKETTVK
KAVVVPARSE ALGKEAACES STPSWASDHN YNAVKPEKTA APSPSLLYKC SGKYSYSLHA
SLIA
//
