ID   A0A2K5LYA8_CERAT        Unreviewed;       605 AA.
AC   A0A2K5LYA8;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   24-JAN-2024, entry version 27.
DE   SubName: Full=SH3 domain binding protein 2 {ECO:0000313|Ensembl:ENSCATP00000017937.1};
GN   Name=SH3BP2 {ECO:0000313|Ensembl:ENSCATP00000017937.1};
OS   Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Cercocebus.
OX   NCBI_TaxID=9531 {ECO:0000313|Ensembl:ENSCATP00000017937.1, ECO:0000313|Proteomes:UP000233060};
RN   [1] {ECO:0000313|Ensembl:ENSCATP00000017937.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   RefSeq; XP_011914601.1; XM_012059211.1.
DR   AlphaFoldDB; A0A2K5LYA8; -.
DR   STRING; 9531.ENSCATP00000017937; -.
DR   Ensembl; ENSCATT00000042108.1; ENSCATP00000017937.1; ENSCATG00000032838.1.
DR   GeneID; 105585468; -.
DR   KEGG; caty:105585468; -.
DR   CTD; 6452; -.
DR   GeneTree; ENSGT00390000002216; -.
DR   OrthoDB; 5473346at2759; -.
DR   Proteomes; UP000233060; Unplaced.
DR   Bgee; ENSCATG00000032838; Expressed in spleen and 12 other cell types or tissues.
DR   GO; GO:0001784; F:phosphotyrosine residue binding; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   CDD; cd13308; PH_3BP2; 1.
DR   CDD; cd10359; SH2_SH3BP2; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   Gene3D; 3.30.505.10; SH2 domain; 1.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR001849; PH_domain.
DR   InterPro; IPR000980; SH2.
DR   InterPro; IPR036860; SH2_dom_sf.
DR   InterPro; IPR035848; SH3BP2.
DR   InterPro; IPR035847; SH3BP2_SH2.
DR   PANTHER; PTHR15126:SF4; SH3 DOMAIN-BINDING PROTEIN 2; 1.
DR   PANTHER; PTHR15126; SH3-BINDING; 1.
DR   Pfam; PF00169; PH; 1.
DR   Pfam; PF00017; SH2; 1.
DR   SMART; SM00233; PH; 1.
DR   SMART; SM00252; SH2; 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   SUPFAM; SSF55550; SH2 domain; 1.
DR   PROSITE; PS50003; PH_DOMAIN; 1.
DR   PROSITE; PS50001; SH2; 1.
PE   4: Predicted;
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233060};
KW   SH2 domain {ECO:0000256|ARBA:ARBA00022999, ECO:0000256|PROSITE-
KW   ProRule:PRU00191}.
FT   DOMAIN          70..174
FT                   /note="PH"
FT                   /evidence="ECO:0000259|PROSITE:PS50003"
FT   DOMAIN          501..599
FT                   /note="SH2"
FT                   /evidence="ECO:0000259|PROSITE:PS50001"
FT   REGION          181..360
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          377..497
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        244..259
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        275..289
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        292..307
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        308..323
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        422..436
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        459..483
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   605 AA;  66591 MW;  AE76AE0ECFEF1282 CRC64;
     MEAGARDEAA AAGGRGLGPC RCSQGRRAWT APGKPAVSAA WTPFMAAEEM HWPVPMKAIG
     AQNLLTMPGG VAKAGYLHKK GGTQLQLLKW PLRFVIIHKR CVYYFKSSTS ASPQGAFSLS
     GYNRVMRAAE ETTSNNVFPF KIIHISKKHR TWFFSASSED ERKSWMALLR REIGHFHEKR
     DLPLDTSDSS SDTDSFYGAV ERPVDISLSP YPTDNEDYEH DDEDDSYMEP DSPEPGRLED
     ALTHPPAYPP PPVPTPRKPA FSDMPRAHSF TSKGPGPLLP PPPPKHGLPD VGPAAEDSKR
     EPLGPRRAEP CPRVPPTPRR MSDPPLGTMP TTPGLRKPPC FRESASPSPE PWTPGHGACS
     TSSVAIMATA TSRNCDKLKS FHLSPRGPPT SEPPPVPANK PKFLKTAEED PPREAAMPGL
     FVPPVAPRPP ALKLPVPEAM ARPAVLPRPE KPQLPHLQRS PPDGQSFRSF SFEKPQQPSQ
     ADAGGDDSDE DYEKVPLPNS VFINTTESCE VERLFKATSP RGEPQDGLYC IRNSSTKSGK
     VLVVWDEASN KVRNYRIFEK DSKFYLEGEV LFVSVGSMVE HYHTHVLPSH QSLLLRHPYG
     YTGPR
//