ID A0A2K5LYW5_CERAT Unreviewed; 396 AA.
AC A0A2K5LYW5;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Cell adhesion molecule 3 {ECO:0000313|Ensembl:ENSCATP00000018139.1};
GN Name=CADM3 {ECO:0000313|Ensembl:ENSCATP00000018139.1};
OS Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Cercocebus.
OX NCBI_TaxID=9531 {ECO:0000313|Ensembl:ENSCATP00000018139.1, ECO:0000313|Proteomes:UP000233060};
RN [1] {ECO:0000313|Ensembl:ENSCATP00000018139.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
CC -!- SIMILARITY: Belongs to the nectin family.
CC {ECO:0000256|ARBA:ARBA00007810}.
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DR RefSeq; XP_011948701.1; XM_012093311.1.
DR AlphaFoldDB; A0A2K5LYW5; -.
DR SMR; A0A2K5LYW5; -.
DR Ensembl; ENSCATT00000042313.1; ENSCATP00000018139.1; ENSCATG00000032936.1.
DR GeneID; 105601249; -.
DR CTD; 57863; -.
DR GeneTree; ENSGT00940000159779; -.
DR OMA; MTQERAL; -.
DR OrthoDB; 3039994at2759; -.
DR Proteomes; UP000233060; Unplaced.
DR Bgee; ENSCATG00000032936; Expressed in cerebellum and 7 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR CDD; cd07705; IgI_2_Necl-1; 1.
DR CDD; cd05882; IgV_1_Necl-1; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR InterPro; IPR013162; CD80_C2-set.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR013106; Ig_V-set.
DR InterPro; IPR003585; Neurexin-like.
DR PANTHER; PTHR45889:SF5; CELL ADHESION MOLECULE 3; 1.
DR PANTHER; PTHR45889; IG-LIKE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF08205; C2-set_2; 1.
DR Pfam; PF13927; Ig_3; 1.
DR Pfam; PF07686; V-set; 1.
DR SMART; SM00294; 4.1m; 1.
DR SMART; SM00409; IG; 3.
DR SMART; SM00408; IGc2; 3.
DR SUPFAM; SSF48726; Immunoglobulin; 3.
DR PROSITE; PS50835; IG_LIKE; 3.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000233060};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..396
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014388987"
FT TRANSMEM 327..354
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 19..110
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 128..226
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 231..313
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 365..396
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 396 AA; 43185 MW; 6EBD334B1940213E CRC64;
MGAPVALLLL LLFACCWAPS GANLSQDDSQ PWTSDETVVA GGTVVLKCQV KDHEDSSLQW
SNPAQQTLYF GEKRALRDNR IQLVTSTPHE LSISISNVAL ADEGEYTCSI FTMPVRTAKS
LVTVLGIPQK PIITGYKSSL REKDTATLNC QSSGSKPAAR LTWRKGDQEL HGEPTRIQED
PNGKTFTVSS SVTFQVTRED DGANIVCSVN HESLKGADRS TSQRIEVLYT PTAMIRPDPP
HPREGQKLLL HCEGRGNPVP QQYLWEKEGS VPPLKMTQES ALIFPFLNKS DSGTYGCTAT
SNMGSYKAYY TLNVNDPSPV PSSSSTYHAI IGGIVAFIVF LLLIMLIFLG HYLIRHKGTY
LTHEAKGSDD APDADTAIIN AEGGQSGGDD KKEYFI
//
