ID A0A2K5LZ94_CERAT Unreviewed; 334 AA.
AC A0A2K5LZ94;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=Nuclear transcription factor Y subunit gamma {ECO:0000256|ARBA:ARBA00040590};
DE AltName: Full=CAAT box DNA-binding protein subunit C {ECO:0000256|ARBA:ARBA00042333};
DE AltName: Full=Nuclear transcription factor Y subunit C {ECO:0000256|ARBA:ARBA00042663};
GN Name=NFYC {ECO:0000313|Ensembl:ENSCATP00000018266.1};
OS Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Cercocebus.
OX NCBI_TaxID=9531 {ECO:0000313|Ensembl:ENSCATP00000018266.1, ECO:0000313|Proteomes:UP000233060};
RN [1] {ECO:0000313|Ensembl:ENSCATP00000018266.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- FUNCTION: Component of the sequence-specific heterotrimeric
CC transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3'
CC box motif found in the promoters of its target genes. NF-Y can function
CC as both an activator and a repressor, depending on its interacting
CC cofactors. {ECO:0000256|ARBA:ARBA00025263}.
CC -!- SUBUNIT: Heterotrimeric transcription factor composed of three
CC components, NF-YA, NF-YB and NF-YC. NF-YB and NF-YC must interact and
CC dimerize for NF-YA association and DNA binding.
CC {ECO:0000256|ARBA:ARBA00025911}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the NFYC/HAP5 subunit family.
CC {ECO:0000256|ARBA:ARBA00038129}.
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DR AlphaFoldDB; A0A2K5LZ94; -.
DR Ensembl; ENSCATT00000042440.1; ENSCATP00000018266.1; ENSCATG00000032882.1.
DR GeneTree; ENSGT00940000155689; -.
DR Proteomes; UP000233060; Unplaced.
DR Bgee; ENSCATG00000032882; Expressed in heart and 12 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro.
DR Gene3D; 1.10.20.10; Histone, subunit A; 1.
DR InterPro; IPR009072; Histone-fold.
DR InterPro; IPR007125; Histone_H2A/H2B/H3.
DR PANTHER; PTHR10252; HISTONE-LIKE TRANSCRIPTION FACTOR CCAAT-RELATED; 1.
DR PANTHER; PTHR10252:SF8; NUCLEAR TRANSCRIPTION FACTOR Y SUBUNIT GAMMA; 1.
DR Pfam; PF00125; Histone; 1.
DR SUPFAM; SSF47113; Histone-fold; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000233060};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 23..105
FT /note="Histone H2A/H2B/H3"
FT /evidence="ECO:0000259|Pfam:PF00125"
SQ SEQUENCE 334 AA; 36877 MW; E7811FC772CDAE70 CRC64;
MSTEGGFGGT SSSDAQQSLQ SFWPRVMEEI RNLTVKDFRV QELPLARIKK IMKLDEDVKM
ISAEAPVLFA KAAQIFITEL TLRAWIHTED NKRRTLQRND IAMAITKFDQ FDFLIDIVPR
DELKPPKRQE EVRQSVTPAE PVQYYFTLAQ QPTAVQVQGQ QQGQQTTSST TTIQPGQIII
AQPQQGQTTP VTMQVGEGQQ VQIVQAQPQG QAQQAQSSTG QTMQVMQQII TNTGEIQQIP
VQLNAGQLQY IRLAQPVSGT QVVQGQIQTL ATNAQQVCAP ETQGVTSLSP LHPSQQLYQI
QQVTMPAGQD LAQPMFIQSA NQPSDGQAPQ VTGD
//
