ID A0A2K5M0B1_CERAT Unreviewed; 167 AA.
AC A0A2K5M0B1;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE SubName: Full=BCL2 associated agonist of cell death {ECO:0000313|Ensembl:ENSCATP00000018635.1};
GN Name=BAD {ECO:0000313|Ensembl:ENSCATP00000018635.1};
OS Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Cercocebus.
OX NCBI_TaxID=9531 {ECO:0000313|Ensembl:ENSCATP00000018635.1, ECO:0000313|Proteomes:UP000233060};
RN [1] {ECO:0000313|Ensembl:ENSCATP00000018635.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR RefSeq; XP_011897285.1; XM_012041895.1.
DR AlphaFoldDB; A0A2K5M0B1; -.
DR STRING; 9531.ENSCATP00000018635; -.
DR Ensembl; ENSCATT00000042813.1; ENSCATP00000018635.1; ENSCATG00000033143.1.
DR GeneID; 105577493; -.
DR KEGG; caty:105577493; -.
DR CTD; 572; -.
DR GeneTree; ENSGT00390000010740; -.
DR OMA; SSWTRIF; -.
DR OrthoDB; 3905221at2759; -.
DR Proteomes; UP000233060; Unplaced.
DR Bgee; ENSCATG00000033143; Expressed in heart and 12 other cell types or tissues.
DR GO; GO:0097138; C:BAD-BCL-2 complex; IEA:Ensembl.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0005741; C:mitochondrial outer membrane; IEA:Ensembl.
DR GO; GO:0008656; F:cysteine-type endopeptidase activator activity involved in apoptotic process; IEA:Ensembl.
DR GO; GO:0005543; F:phospholipid binding; IEA:Ensembl.
DR GO; GO:0019901; F:protein kinase binding; IEA:Ensembl.
DR GO; GO:0019903; F:protein phosphatase binding; IEA:Ensembl.
DR GO; GO:0046031; P:ADP metabolic process; IEA:Ensembl.
DR GO; GO:0046034; P:ATP metabolic process; IEA:Ensembl.
DR GO; GO:0071456; P:cellular response to hypoxia; IEA:Ensembl.
DR GO; GO:0071396; P:cellular response to lipid; IEA:Ensembl.
DR GO; GO:0071260; P:cellular response to mechanical stimulus; IEA:Ensembl.
DR GO; GO:0071316; P:cellular response to nicotine; IEA:Ensembl.
DR GO; GO:0019221; P:cytokine-mediated signaling pathway; IEA:Ensembl.
DR GO; GO:0097192; P:extrinsic apoptotic signaling pathway in absence of ligand; IEA:Ensembl.
DR GO; GO:0008625; P:extrinsic apoptotic signaling pathway via death domain receptors; IEA:Ensembl.
DR GO; GO:0006007; P:glucose catabolic process; IEA:Ensembl.
DR GO; GO:0042593; P:glucose homeostasis; IEA:Ensembl.
DR GO; GO:0008630; P:intrinsic apoptotic signaling pathway in response to DNA damage; IEA:Ensembl.
DR GO; GO:0046931; P:pore complex assembly; IEA:Ensembl.
DR GO; GO:0045579; P:positive regulation of B cell differentiation; IEA:Ensembl.
DR GO; GO:0050679; P:positive regulation of epithelial cell proliferation; IEA:Ensembl.
DR GO; GO:0035774; P:positive regulation of insulin secretion involved in cellular response to glucose stimulus; IEA:Ensembl.
DR GO; GO:1902220; P:positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress; IEA:Ensembl.
DR GO; GO:0010918; P:positive regulation of mitochondrial membrane potential; IEA:Ensembl.
DR GO; GO:0045862; P:positive regulation of proteolysis; IEA:Ensembl.
DR GO; GO:0090200; P:positive regulation of release of cytochrome c from mitochondria; IEA:Ensembl.
DR GO; GO:0045582; P:positive regulation of T cell differentiation; IEA:Ensembl.
DR GO; GO:2000078; P:positive regulation of type B pancreatic cell development; IEA:Ensembl.
DR GO; GO:0046902; P:regulation of mitochondrial membrane permeability; IEA:Ensembl.
DR GO; GO:0001836; P:release of cytochrome c from mitochondria; IEA:Ensembl.
DR GO; GO:0044342; P:type B pancreatic cell proliferation; IEA:Ensembl.
DR InterPro; IPR018868; BAD.
DR PANTHER; PTHR28540; BCL2-ASSOCIATED AGONIST OF CELL DEATH; 1.
DR PANTHER; PTHR28540:SF1; BCL2-ASSOCIATED AGONIST OF CELL DEATH; 1.
DR Pfam; PF10514; Bcl-2_BAD; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000233060}.
FT REGION 1..104
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 125..144
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 47..64
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 167 AA; 18527 MW; B8D9032E6AD05FB0 CRC64;
MFQIPEFEPS EQEDSSSAER GLGPSLAGDR PSDCGKHHRQ APGLLWDASH QQEQPTSSSH
HGGAGAVETR SRHSSYPAGT EEDEGMEEEP SPFRGRSRSA PPNLWAAQRY GRELRRMSDE
FVDSFKGLPR PKSAGTATQM RQSSSWTRVF QSWWDRNLGR GSSAPSQ
//
