ID A0A2K5M231_CERAT Unreviewed; 450 AA.
AC A0A2K5M231;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Forkhead box O4 {ECO:0000313|Ensembl:ENSCATP00000019244.1};
GN Name=FOXO4 {ECO:0000313|Ensembl:ENSCATP00000019244.1};
OS Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Cercocebus.
OX NCBI_TaxID=9531 {ECO:0000313|Ensembl:ENSCATP00000019244.1, ECO:0000313|Proteomes:UP000233060};
RN [1] {ECO:0000313|Ensembl:ENSCATP00000019244.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00089}.
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DR AlphaFoldDB; A0A2K5M231; -.
DR Ensembl; ENSCATT00000043425.1; ENSCATP00000019244.1; ENSCATG00000033404.1.
DR GeneTree; ENSGT00940000159334; -.
DR Proteomes; UP000233060; Unplaced.
DR Bgee; ENSCATG00000033404; Expressed in skeletal muscle tissue and 12 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR001766; Fork_head_dom.
DR InterPro; IPR032067; FOXO-TAD.
DR InterPro; IPR030456; TF_fork_head_CS_2.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR45767; FORKHEAD BOX PROTEIN O; 1.
DR PANTHER; PTHR45767:SF3; FORKHEAD BOX PROTEIN O4; 1.
DR Pfam; PF00250; Forkhead; 1.
DR Pfam; PF16676; FOXO-TAD; 1.
DR PRINTS; PR00053; FORKHEAD.
DR SMART; SM00339; FH; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00658; FORK_HEAD_2; 1.
DR PROSITE; PS50039; FORK_HEAD_3; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00089}; Nucleus {ECO:0000256|PROSITE-ProRule:PRU00089};
KW Reference proteome {ECO:0000313|Proteomes:UP000233060}.
FT DOMAIN 46..140
FT /note="Fork-head"
FT /evidence="ECO:0000259|PROSITE:PS50039"
FT DNA_BIND 46..140
FT /note="Fork-head"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00089"
FT REGION 1..58
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 121..218
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 200..217
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 450 AA; 47878 MW; F0D756FA67DBF85B CRC64;
MDPGNKNSAT EAAAVIDLDP DFEPQSRPRS CTWPLPRPEI ANQPSETPEV EPGLGEKAIE
SAPEKRLTLA QIYEWMVRTV PYFKDKGDSN SSAGWKNSIR HNLSLHSKFI KVHNEATGKS
SWWMLNPEGG KSGKAPRRRA ASMDSSSKLL RGRSKAPKKK PPVLPAPPEG ATPTSPAGHF
AKWSGSPCSR NREEADMWTT FRPRSSSNAS TVSTRLSPLR PEPEVLAEEI PASVSSYAGG
VPPTLNEGLE LLDGLNLTSS HSLLSRSGLS GFSLQHPGVT GPLHTYSSSL FSPAEGPLSA
GEGCFSSSQA LEALLTSDTP PPPADVLMTQ VDPILSQAPT LLLLGGLPSS SKLATGVGLC
PKPLEAPGPS SLVPTLSMIA PPPVMASAPI PKALGTPVLT PPTEAASQDR MPQDLDLDMY
MENLECDMDN IISDLMDEGE GLDFNFEPDP
//
