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Database: UniProt
Entry: A0A2K5M3B2_CERAT
LinkDB: A0A2K5M3B2_CERAT
Original site: A0A2K5M3B2_CERAT 
ID   A0A2K5M3B2_CERAT        Unreviewed;       641 AA.
AC   A0A2K5M3B2;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   31-JUL-2019, entry version 12.
DE   RecName: Full=ENTH domain-containing protein {ECO:0000259|PROSITE:PS50942};
GN   Name=EPN2 {ECO:0000313|Ensembl:ENSCATP00000019680};
OS   Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Cercopithecidae; Cercopithecinae; Cercocebus.
OX   NCBI_TaxID=9531 {ECO:0000313|Ensembl:ENSCATP00000019680, ECO:0000313|Proteomes:UP000233060};
RN   [1] {ECO:0000313|Ensembl:ENSCATP00000019680, ECO:0000313|Proteomes:UP000233060}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Liu Y., Hughes D.S., Murali S., Raveendran M., Korchina V., Wang M.,
RA   Jhangiani S., Bandaranaike D., Bellair M., Blankenburg K., Chao H.,
RA   Dahdouli M., Dinh H., Doddapaneni H., English A., Firestine M.,
RA   Gross S., Hernandez B., Javaid M., Jayaseelan J., Jones J., Joshi V.,
RA   Khan Z., Kovar C., Lee S., Newsham I., Nguyen L., Okwuonu G.,
RA   Ongeri F., Osuji N., Pu L.-L., Puazo M., Qu C., Quiroz J., Raj R.,
RA   Reid J.G., Santibanez J., Scheel M., Sexton D., Shah N., Skinner E.,
RA   Vee V., Wu Y., Han Y., Muzny D.M., Richards S., Worley K.C.,
RA   Rogers J., Gibbs R.A.;
RT   "Sooty reference genome and diversity panel.";
RL   Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSCATP00000019680}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2018) to UniProtKB.
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DR   RefSeq; XP_011932546.1; XM_012077156.1.
DR   RefSeq; XP_011932547.1; XM_012077157.1.
DR   RefSeq; XP_011932548.1; XM_012077158.1.
DR   Ensembl; ENSCATT00000043864; ENSCATP00000019680; ENSCATG00000033631.
DR   GeneID; 105593713; -.
DR   CTD; 22905; -.
DR   GeneTree; ENSGT00940000157239; -.
DR   OrthoDB; 1263849at2759; -.
DR   Proteomes; UP000233060; Whole Genome Shotgun Assembly.
DR   GO; GO:0030128; C:clathrin coat of endocytic vesicle; IEA:InterPro.
DR   GO; GO:0043231; C:intracellular membrane-bounded organelle; IEA:Ensembl.
DR   GO; GO:0006897; P:endocytosis; IEA:InterPro.
DR   GO; GO:1903671; P:negative regulation of sprouting angiogenesis; IEA:Ensembl.
DR   GO; GO:0030948; P:negative regulation of vascular endothelial growth factor receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0045747; P:positive regulation of Notch signaling pathway; IEA:Ensembl.
DR   Gene3D; 1.25.40.90; -; 1.
DR   InterPro; IPR013809; ENTH.
DR   InterPro; IPR008942; ENTH_VHS.
DR   InterPro; IPR027319; Epsin-2_metazoa.
DR   InterPro; IPR003903; UIM_dom.
DR   PANTHER; PTHR12276:SF50; PTHR12276:SF50; 1.
DR   Pfam; PF01417; ENTH; 1.
DR   SMART; SM00273; ENTH; 1.
DR   SMART; SM00726; UIM; 2.
DR   SUPFAM; SSF48464; SSF48464; 1.
DR   PROSITE; PS50942; ENTH; 1.
DR   PROSITE; PS50330; UIM; 2.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000233060};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233060}.
FT   DOMAIN       12    144       ENTH. {ECO:0000259|PROSITE:PS50942}.
FT   REGION      163    214       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION      343    428       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION      469    512       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   COILED       10     30       {ECO:0000256|SAM:Coils}.
FT   COILED      123    143       {ECO:0000256|SAM:Coils}.
FT   COMPBIAS    163    186       Polar. {ECO:0000256|SAM:MobiDB-lite}.
FT   COMPBIAS    354    369       Polar. {ECO:0000256|SAM:MobiDB-lite}.
FT   COMPBIAS    395    428       Polar. {ECO:0000256|SAM:MobiDB-lite}.
FT   COMPBIAS    469    510       Polar. {ECO:0000256|SAM:MobiDB-lite}.
SQ   SEQUENCE   641 AA;  68472 MW;  5B685A2F9558938E CRC64;
     MTTSSIRRQM KNIVNNYSEA EIKVREATSN DPWGPSSSLM TEIADLTYNV VAFSEIMSMV
     WKRLNDHGKN WRHVYKALTL LDYLIKTGSE RVAQQCRENI FAIQTLKDFQ YIDRDGKDQG
     INVREKSKQL VALLKDEERL KAERAQALKT KERMAQVATG MGSNQITFGR GSSQPNLSTS
     HSEQEYGKAG GSPASYHGSP EASLCPQHRT GAPLGQSEEL QPLSQRHPFL PHLGLASRPN
     GDWSQPCLTC DRAARATSPR VSSELEQARP QTSGEEELQL QLALAMSREV AEQEERLRRG
     DDLRLQMALE ESRRDTVKIP KKKEHGSLPQ QTTLLDLMDA LPSSGLPAQK VEPWGPSAST
     NQTNPWGRPA APASASDPWP SFGTKPAASV DPWGVPTGAS TQSVPKNSDP WAASQQPASG
     AGKTASDAWG AVSSTKPVSA SGSFELFSNL NGTIKDDFSE FDNLRTSKRT AESVTSLPSQ
     NNGTTSPDPF ESQPLTVASS KPSSARKTPE SFLGPNAALV NLDSLVTRPA PPAQSLNPFL
     APGAPATSAP VNPFQVNQPQ PLTLNQLRGS PVLGTSTSFG PGPGVESVAV ASMTSTAPHP
     ALGATGSSLT PLGPATMNMV GSVGIPPSAA QATGTTNPFL L
//
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