ID A0A2K5M3G7_CERAT Unreviewed; 329 AA.
AC A0A2K5M3G7;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE SubName: Full=CD86 molecule {ECO:0000313|Ensembl:ENSCATP00000019735.1};
GN Name=CD86 {ECO:0000313|Ensembl:ENSCATP00000019735.1};
OS Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Cercocebus.
OX NCBI_TaxID=9531 {ECO:0000313|Ensembl:ENSCATP00000019735.1, ECO:0000313|Proteomes:UP000233060};
RN [1] {ECO:0000313|Ensembl:ENSCATP00000019735.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
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DR RefSeq; XP_011923905.1; XM_012068515.1.
DR AlphaFoldDB; A0A2K5M3G7; -.
DR STRING; 9531.ENSCATP00000019735; -.
DR Ensembl; ENSCATT00000043919.1; ENSCATP00000019735.1; ENSCATG00000033649.1.
DR GeneID; 105589768; -.
DR CTD; 942; -.
DR GeneTree; ENSGT00940000161500; -.
DR OMA; LPCQFTN; -.
DR OrthoDB; 4633735at2759; -.
DR Proteomes; UP000233060; Unplaced.
DR Bgee; ENSCATG00000033649; Expressed in spleen and 8 other cell types or tissues.
DR GO; GO:0034451; C:centriolar satellite; IEA:Ensembl.
DR GO; GO:0070062; C:extracellular exosome; IEA:Ensembl.
DR GO; GO:0005886; C:plasma membrane; IEA:Ensembl.
DR GO; GO:0048018; F:receptor ligand activity; IEA:Ensembl.
DR GO; GO:0042110; P:T cell activation; IEA:Ensembl.
DR CDD; cd16087; IgV_CD86; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR InterPro; IPR037677; CD86_IgV.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR013106; Ig_V-set.
DR PANTHER; PTHR25466; T-LYMPHOCYTE ACTIVATION ANTIGEN; 1.
DR PANTHER; PTHR25466:SF2; T-LYMPHOCYTE ACTIVATION ANTIGEN CD86; 1.
DR Pfam; PF07686; V-set; 1.
DR SMART; SM00409; IG; 1.
DR SMART; SM00406; IGv; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000233060};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..30
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 31..329
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014388989"
FT TRANSMEM 246..268
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 33..131
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 276..308
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 289..306
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 329 AA; 37664 MW; 5A5322F76D63E0C8 CRC64;
MDPQCTMGLS NTLFVMAFLL SGAAPLKIQA YFNETADLPC QFANSQNRSL SELVVFWQNQ
ENLVLNEVYL GREKFDSVHS KYMGRTSFDP DSWTLRLHNL QIKDKGLYQC IIHHKRPTGM
IRIHQMNSEL SVLANFSQPE IVPISNITEN MYINLTCSSI HGYPEPEKMS VLLRTKNSTI
EYDGVMQKSQ DNVTELYDVS ISLSVSFPDV TSNMTIFCVL ETDKTQLLSS PFSIELEDPQ
PPPDHIPWIT AVLPTVIICV MAFCLILWKW KKKKQPRNSY NCGTNTMERE ESEQTKKREK
INVPERSDEA QCVFKSLKTP SCDKSDTHF
//
