ID A0A2K5M4M6_CERAT Unreviewed; 874 AA.
AC A0A2K5M4M6;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Neural cell adhesion molecule 1 {ECO:0000313|Ensembl:ENSCATP00000020148.1};
GN Name=NCAM1 {ECO:0000313|Ensembl:ENSCATP00000020148.1};
OS Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Cercocebus.
OX NCBI_TaxID=9531 {ECO:0000313|Ensembl:ENSCATP00000020148.1, ECO:0000313|Proteomes:UP000233060};
RN [1] {ECO:0000313|Ensembl:ENSCATP00000020148.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- FUNCTION: This protein is a cell adhesion molecule involved in neuron-
CC neuron adhesion, neurite fasciculation, outgrowth of neurites, etc.
CC {ECO:0000256|ARBA:ARBA00003000}.
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DR AlphaFoldDB; A0A2K5M4M6; -.
DR Ensembl; ENSCATT00000044334.1; ENSCATP00000020148.1; ENSCATG00000032945.1.
DR GeneTree; ENSGT00940000155743; -.
DR OMA; DSKQKGQ; -.
DR Proteomes; UP000233060; Unplaced.
DR Bgee; ENSCATG00000032945; Expressed in frontal cortex and 8 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR CDD; cd00063; FN3; 2.
DR CDD; cd00096; Ig; 1.
DR CDD; cd05865; IgI_1_NCAM-1; 1.
DR CDD; cd05869; IgI_NCAM-1; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 7.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR009138; Neural_cell_adh.
DR PANTHER; PTHR12231; CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN; 1.
DR PANTHER; PTHR12231:SF239; NEURAL CELL ADHESION MOLECULE 1; 1.
DR Pfam; PF00041; fn3; 2.
DR Pfam; PF07679; I-set; 2.
DR Pfam; PF13927; Ig_3; 3.
DR PRINTS; PR01838; NCAMFAMILY.
DR SMART; SM00060; FN3; 2.
DR SMART; SM00409; IG; 5.
DR SMART; SM00408; IGc2; 5.
DR SUPFAM; SSF49265; Fibronectin type III; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 5.
DR PROSITE; PS50853; FN3; 2.
DR PROSITE; PS50835; IG_LIKE; 5.
PE 4: Predicted;
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000233060};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 739..762
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 17..108
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 113..186
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 209..298
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 305..430
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 433..518
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 526..625
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 627..722
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 782..874
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 783..824
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 837..851
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 874 AA; 95863 MW; 004C9B77E3069240 CRC64;
VSPPSDCVWT AWGTASLQVD IVPSQGEISV GESKFFLCQV AGDAKDKDIS WFSPNGEKLT
PNQQRISVVW NDDSSSTLTI YNANIDDAGI YKCVVTGEDG SESEATVNVK IFQKLMFKNA
PTPQEFREGE DAVIVCDVVS SLPPTIIWKH KGRDVILKKD VRFIVLSNNY LQIRGIKKTD
EGTYRCEGRI LARGEINFKD IQVVVNVPPT IQARQNIVNA TANLGQSVTL VCDAEGFPEP
TMSWTKDGEQ IEQEEDDEKY IFSDDSSQLT IKKVDKNDEA EYICIAENKA GEQDATIHLK
VFAKPKITYV ENQTAMELEE QVTLTCEASG DPIPSITWRT STRNISSEEK VSCCPGVSGP
WNVDRQKGQG GNAVFPASHE TLDGHMVVRS HARVSSLTLK SIQYTDAGEY ICTASNTIGQ
DSQSMYLEVQ YAPKLQGPVA VYTWEGNQVN ITCEVFAYPS ATISWFRDGQ LLPSSNYSNI
KIYNTPSASY LEVTPDSEND FGNYNCTAVN RIGQESLEFI LVQADTPSSP SIDQVEPYSS
TAQVQFDEPE ATGGVPILKY KAEWRAVGEE VWHSKWYDAK EASMEGIVTI VGLKPETTYA
VRLAALNGKG LGEISAASEF KTQPVREPSA PKLEGQMGED GNSIKVNLIK QDDGGSPIRH
YLVRYRALSS EWKPEIRLPS GSDHVMLKSL DWNAEYEVYV VAENQQGKSK AAHFVFRTSA
QPTAIPANGS PTSGLSTGAI VGILIVIFVL LLVVVDITCY FLNKCGLFMC IAVNLCGKAG
PGAKGKDMEE GKAAFSKDES KEPIVEVRTE EERTPNHDGG KHTEPNETTP LTEPEKGPVE
AKPECQETET KPAPAEVKTV PNDATQTKEN ESKA
//
