ID A0A2K5M6B6_CERAT Unreviewed; 370 AA.
AC A0A2K5M6B6;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE SubName: Full=Leucine rich repeat containing 19 {ECO:0000313|Ensembl:ENSCATP00000020740.1};
GN Name=LRRC19 {ECO:0000313|Ensembl:ENSCATP00000020740.1};
OS Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Cercocebus.
OX NCBI_TaxID=9531 {ECO:0000313|Ensembl:ENSCATP00000020740.1, ECO:0000313|Proteomes:UP000233060};
RN [1] {ECO:0000313|Ensembl:ENSCATP00000020740.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR RefSeq; XP_011927281.1; XM_012071891.1.
DR RefSeq; XP_011927282.1; XM_012071892.1.
DR AlphaFoldDB; A0A2K5M6B6; -.
DR STRING; 9531.ENSCATP00000020740; -.
DR Ensembl; ENSCATT00000044932.1; ENSCATP00000020740.1; ENSCATG00000034126.1.
DR GeneID; 105591296; -.
DR KEGG; caty:105591296; -.
DR CTD; 64922; -.
DR GeneTree; ENSGT00940000161278; -.
DR OMA; EVKCNFT; -.
DR OrthoDB; 5353250at2759; -.
DR Proteomes; UP000233060; Unplaced.
DR Bgee; ENSCATG00000034126; Expressed in adult mammalian kidney and 12 other cell types or tissues.
DR GO; GO:0005886; C:plasma membrane; IEA:Ensembl.
DR GO; GO:0038023; F:signaling receptor activity; IEA:Ensembl.
DR GO; GO:0048874; P:host-mediated regulation of intestinal microbiota composition; IEA:Ensembl.
DR GO; GO:1901224; P:positive regulation of non-canonical NF-kappaB signal transduction; IEA:Ensembl.
DR GO; GO:0001817; P:regulation of cytokine production; IEA:Ensembl.
DR GO; GO:0050727; P:regulation of inflammatory response; IEA:Ensembl.
DR GO; GO:0002224; P:toll-like receptor signaling pathway; IEA:Ensembl.
DR GO; GO:0038008; P:TRAF-mediated signal transduction; IEA:Ensembl.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR InterPro; IPR000483; Cys-rich_flank_reg_C.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR PANTHER; PTHR31450:SF4; LEUCINE-RICH REPEAT-CONTAINING PROTEIN 19; 1.
DR PANTHER; PTHR31450; LEUCINE-RICH REPEAT-CONTAINING PROTEIN 19 LRRC19 FAMILY MEMBER; 1.
DR Pfam; PF15176; LRR19-TM; 1.
DR Pfam; PF13855; LRR_8; 1.
DR SMART; SM00369; LRR_TYP; 4.
DR SMART; SM00082; LRRCT; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
PE 4: Predicted;
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000233060};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..370
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014388995"
FT TRANSMEM 270..291
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 176..227
FT /note="LRRCT"
FT /evidence="ECO:0000259|SMART:SM00082"
SQ SEQUENCE 370 AA; 42341 MW; 27607FD1EE8B2B1E CRC64;
MKVTGITILF WPLSMVLLSD KIQSSKREVQ CNFTEKNYSL IPADIKKDVT ILDLSYNQIT
LNGTDTRVLQ TYFLLTELYL IENNVTVLHN NSFDNLSSLE ILNICRNSIY VIQQGAFLGL
NKLKQLHLCQ NKIEQLNADI FVPLRDLKLL NLQGNLISYL DVPPLFHLEL ITLYGNLWNC
SCSLFNLQNW LNTSNVTLEN ENITMCSYPN SLKSYNIKTV PPKAECHSKL PSPVTEDLYI
HFQPISNSTF NSSLNNLTRN SEHIPLGKSW AFLVGVVVTA LTTSLLIFIA IKCPIWYNIL
LSYNHHRLEE HEAETYEDGF TGNPSSLSQI PETNSEETTV IFEQLHSFVV DDDGFIEDKY
IDIHELREEN
//
