ID   A0A2K5M6J5_CERAT        Unreviewed;       196 AA.
AC   A0A2K5M6J5;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218};
GN   Name=TSPAN2 {ECO:0000313|Ensembl:ENSCATP00000020823.1};
OS   Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Cercocebus.
OX   NCBI_TaxID=9531 {ECO:0000313|Ensembl:ENSCATP00000020823.1, ECO:0000313|Proteomes:UP000233060};
RN   [1] {ECO:0000313|Ensembl:ENSCATP00000020823.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC       ECO:0000256|RuleBase:RU361218}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU361218}.
CC   -!- SIMILARITY: Belongs to the tetraspanin (TM4SF) family.
CC       {ECO:0000256|ARBA:ARBA00006840, ECO:0000256|RuleBase:RU361218}.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC       feature annotation. {ECO:0000256|RuleBase:RU361218}.
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DR   AlphaFoldDB; A0A2K5M6J5; -.
DR   Ensembl; ENSCATT00000045017.1; ENSCATP00000020823.1; ENSCATG00000034149.1.
DR   GeneTree; ENSGT00940000157504; -.
DR   Proteomes; UP000233060; Unplaced.
DR   Bgee; ENSCATG00000034149; Expressed in colon and 12 other cell types or tissues.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   CDD; cd03151; CD81_like_LEL; 1.
DR   Gene3D; 1.10.1450.10; Tetraspanin; 1.
DR   InterPro; IPR018499; Tetraspanin/Peripherin.
DR   InterPro; IPR000301; Tetraspanin_animals.
DR   InterPro; IPR018503; Tetraspanin_CS.
DR   InterPro; IPR008952; Tetraspanin_EC2_sf.
DR   PANTHER; PTHR19282; TETRASPANIN; 1.
DR   PANTHER; PTHR19282:SF155; TETRASPANIN-2; 1.
DR   Pfam; PF00335; Tetraspanin; 2.
DR   PIRSF; PIRSF002419; Tetraspanin; 2.
DR   PRINTS; PR00259; TMFOUR.
DR   SUPFAM; SSF48652; Tetraspanin; 1.
DR   PROSITE; PS00421; TM4_1; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU361218};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233060};
KW   Transmembrane {ECO:0000256|RuleBase:RU361218};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU361218}.
FT   TRANSMEM        20..42
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361218"
FT   TRANSMEM        54..75
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361218"
FT   TRANSMEM        163..185
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361218"
SQ   SEQUENCE   196 AA;  21589 MW;  652E590FA36268BC CRC64;
     KKRFRGGKKN IKYLQKKINL LFKLAGSAVI AFGLWFRFGG AIKELSSEDK SPEYFYVGLY
     VLVGAGALMM AVGFFGCCGA MRESQCVLGS AIRHVQTMYE EAYNDYLKDR GKGNGTLITF
     HSTFQCCGKE SSEQVQPTCP KELLGHKNCI DEIETIISVK LQLIGIVGIG IAGLTIFGMI
     FSMVLCCAIR NSRDVI
//